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Dehydration is a condition caused by the loss of too much water from the body. Severe diarrhea or vomiting can cause dehydration.
Taking antibiotics for diarrhea may put travelers at increased risk for contracting superbugs

Taking antibiotics for diarrhea may put travelers at increased risk for contracting superbugs

Taking antibiotics for diarrhea may put travelers visiting developing parts of the world at higher risk for contracting superbugs and spreading these daunting drug-resistant bacteria to their home countries, according to a new study published in Clinical Infectious Diseases and now available online. [More]
Almost 42% of US drinkers use alcohol-interactive prescription medications, study finds

Almost 42% of US drinkers use alcohol-interactive prescription medications, study finds

Approximately 71 percent of American adults drink alcohol. While alcohol interacts negatively with a number of commonly prescribed medications, little is known on a population level about the use of alcohol-interactive (AI) prescription medication among US drinkers. A new study has found that almost 42 percent of drinkers in the US population have used one or more alcohol-interactive prescription medications. [More]
FDA grants orphan drug status to NBI-77860 for treatment of congenital adrenal hyperplasia

FDA grants orphan drug status to NBI-77860 for treatment of congenital adrenal hyperplasia

Neurocrine Biosciences, Inc. announced today that NBI-77860, a proprietary corticotropin releasing factor 1 (CRF) receptor antagonist, has been granted orphan drug status by the United States Food and Drug Administration (FDA) for the treatment of congenital adrenal hyperplasia (CAH) a disease that affects approximately 20,000-30,000 people in the United States. [More]
Arcturus to exhibit new mRNA therapeutics pipeline at two healthcare conferences

Arcturus to exhibit new mRNA therapeutics pipeline at two healthcare conferences

Arcturus Therapeutics Inc., developing the 'next wave' of RNA medicines, today announced that Joseph Payne, President and Chief Executive Officer, is scheduled to present a corporate overview, including the company's new messenger RNA (mRNA) therapeutics pipeline, at two upcoming healthcare conferences. [More]
Synthetic Biologics doses first patient in SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics doses first patient in SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced that enrollment has initiated and the first patient was dosed in a Phase 1b clinical trial of SYN-004, an investigational oral beta-lactamase enzyme for the prevention of Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy. [More]
FDA approves Novo Nordisk’s weight loss injection, Saxenda

FDA approves Novo Nordisk’s weight loss injection, Saxenda

Novo Nordisk today announced that the Food and Drug Administration (FDA) has approved the new drug application (NDA) for Saxenda® (liraglutide [rDNA origin] injection), the first once-daily glucagon-like peptide-1 (GLP-1) receptor agonist for chronic weight management. [More]
Periods of extreme heat associated with increased hospitalization risk for older adults

Periods of extreme heat associated with increased hospitalization risk for older adults

Between 1999 and 2010, periods of extreme heat in the U.S. were associated with an increased risk of hospitalization for older adults for fluid and electrolyte disorders, kidney failure, urinary tract infections, septicemia and heat stroke, according to a study in the December 24/31 issue of JAMA. [More]
Figitumumab development discontinued for non-adenocarcinoma NSCLC

Figitumumab development discontinued for non-adenocarcinoma NSCLC

Adding the novel insulin-like growth factor 1 receptor inhibitor figitumumab to the epidermal growth factor receptor–tyrosine kinase inhibitor erlotinib does not improve survival in patients with non-adenocarcinoma non-small-cell lung carcinoma, research shows. [More]
Danish researchers working on new type of vaccine that targets disease causing bacterium

Danish researchers working on new type of vaccine that targets disease causing bacterium

When we acquire diarrhea on a vacation, it is often caused by a bacterial infection. Now a Danish research team is working on a new type of vaccine design targeting the disease causing bacterium - if it works it may very well revolutionize not only the prevention of this disease, but also offer protection against other pathogens with a heavy disease burden such as Mycobacterium tuberculosis and antibiotic-resistant Staphylococcus aureus (MRSA). [More]
UB study creates new awareness for diabetics who are at risk for dehydration

UB study creates new awareness for diabetics who are at risk for dehydration

Some drugs used to treat diabetes mimic the behavior of a hormone that a University at Buffalo psychologist has learned controls fluid intake in subjects. The finding creates new awareness for diabetics who, by the nature of their disease, are already at risk for dehydration. [More]
Tips to reduce migraine risk during holiday season

Tips to reduce migraine risk during holiday season

Certain foods and drinks can trigger migraine in many people, and those who suffer from migraines need to be especially careful to avoid these triggers as they attend holiday celebrations. With this in mind, the American Migraine Foundation and its Chair, David W. Dodick, MD, FRCP (C), FACP, want to help people with migraine avoid these potential triggers, so that they can better enjoy the season. Dr. Dodick is also Professor of Medicine at the Mayo Clinic College of Medicine (Scottsdale, AZ). [More]
Gout attacks are most common at night

Gout attacks are most common at night

Research, published today, has shown that an acute gout attack is more than twice as likely to occur during the night or early morning hours as during the day. The increased prevalence of gout attacks at night time was observed even after 24 hours with no alcohol and low purine intake. [More]
New study details weight loss patterns of breastfed newborns

New study details weight loss patterns of breastfed newborns

Using weights obtained from over 100,000 Northern California babies, a new study is the first to detail the weight loss patterns of exclusively breastfed newborns. The results show that some breastfed babies lose weight faster and for a longer period than was previously recognized. [More]
Kessler Institute provides tips to help reduce risk of injury during winter months

Kessler Institute provides tips to help reduce risk of injury during winter months

Winter appears to have arrived early, bringing with it record snowfalls and cold temperatures across the country. It also brings an increased risk for injuries. Whether shoveling snow, dealing with icy roads, or simply trying to walk on wet, slippery pavement, caution is the key word. [More]
New guideline now available to help prevent, treat delirium in older patients

New guideline now available to help prevent, treat delirium in older patients

A new guideline is available to help health care providers prevent and treat one of the most common postoperative complications in older patients, delirium, which is an episode of sudden confusion. [More]
Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen Research & Development, LLC today announced the submission of a New Drug Application (NDA) for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration. The NDA seeks approval for the medication as a treatment for schizophrenia in adults. [More]
Researchers discover new genetic cause of rare, complex form of epilepsy

Researchers discover new genetic cause of rare, complex form of epilepsy

A research team led by scientists at the Scripps Translational Science Institute has used whole genome sequencing to identify a new genetic cause of a severe, rare and complex form of epilepsy that becomes evident in early childhood and can lead to early death. [More]
Working under hot sun causes health problems for sugarcane harvesters

Working under hot sun causes health problems for sugarcane harvesters

Hard work under hot sun causes health problems for sugar cane workers in Costa Rica, such as headache, nausea, and renal dysfunction. The presence of symptoms is also expected to increase in line with ongoing climate changes, according to a dissertation from Umeå University. [More]
The Female Athlete Triad: A medical condition in active girls and women

The Female Athlete Triad: A medical condition in active girls and women

Sophie is a 15 year old cross country runner who has a history of a foot stress fracture and shin splints. Often she does not eat prior to her workouts. [More]
Children from lower-income families more likely to have complications following tonsillectomy

Children from lower-income families more likely to have complications following tonsillectomy

Removing a child's tonsils is one of the most common surgeries performed in the United States, with approximately 500,000 children undergoing the procedure each year. New research finds that children from lower-income families are more likely to have complications following the surgery. [More]