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Dendritic Cell News and Research RSS Feed - Dendritic Cell News and Research

Dendritic Cells are a special type of immune cell that is found in tissues, such as the skin, and boosts immune responses by showing antigens on its surface to other cells of the immune system. A dendritic cell is a type of phagocyte and a type of antigen-presenting cell (APC).

ImmunoCellular Therapeutics presents additional data from its ICT-107 Phase I clinical trial

27. October 2009 09:16
ImmunoCellular Therapeutics, Ltd., a biotechnology company that is focused on the development of novel immune-based cancer therapies, today announced additional data from its Phase I clinical trial evaluating ICT-107, the Company’s dendritic-cell based cancer vaccine product candidate for the treatment of glioblastoma multiforme (GBM). [More]

ImmunoCellular Therapeutics to present Phase I clinical trial data of ICT-107 vaccine in New Orleans

26. October 2009 08:57
ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC), a clinical-stage biotechnology company that is developing immune-based therapies for the treatment of brain and other cancers, today announced that it will be presenting today, at the Annual Meeting of the Congress of Neurological Surgeons in New Orleans, Louisiana at 3:15pm central time, data from its Phase I clinical trial investigating the role that its ICT-107 vaccine may play in increasing patient survival and inhibiting tumor progression in patients with glioblastoma, the most common and most aggressive type of primary brain tumor. [More]

Positive results from Argos Therapeutics' personalized immunotherapy candidate AGS-004 Phase 2a trial

21. October 2009 08:38
Argos Therapeutics today announced two presentations at the AIDS Vaccine 2009 conference, detailing positive viral load, immune response and safety data from an ongoing Phase 2a trial of AGS-004, its personalized immunotherapy candidate. AGS-004 is a product of the Company’s Arcelis™ technology, and is a personalized, RNA-loaded, dendritic cell-based immunotherapy that is perfectly matched to each patient’s unique HIV viral burden. [More]

Northwest Biotherapeutics announces long-term data from Phase I and Phase I/II clinical trials of DCVax-Brain

21. October 2009 08:24
Northwest Biotherapeutics, Inc. today announced further long-term follow-up data, for the period from January through September 2009, from its prior Phase I and Phase I/II clinical trials conducted at UCLA with DCVax®-Brain in patients with Glioblastoma multiforme ("GBM"). GBM is the most rapid and lethal type of brain cancer. During the update period, only one of the twenty patients treated with DCVax®-Brain (in addition to standard of care) died, and that patient had survived for nearly 7 years (80.5 months). [More]

ImmunoCellular Therapeutics files a provisional patent application

20. October 2009 05:29
ImmunoCellular Therapeutics, Ltd., a clinical-stage biotechnology company that is developing immune-based therapies for the treatment of brain and other cancers, announced today that it has filed a provisional patent application at US Patent Office seeking protection of intellectual property relating to novel glycosylated epitopes present in lung cancer, pancreatic cancer and colon cancer that are targeted by the Company’s ICT-109 monoclonal antibody product candidate. [More]

Sangretech Biomedical signs amended license agreement with Bostwick Laboratories

15. October 2009 07:17
Sangretech Biomedical LLC, a developer of dendritic cell therapies for cancer and infectious diseases, today announced it has executed an amended and restated license agreement with Bostwick Laboratories, Inc. providing Bostwick Scientific, the research division of Bostwick Laboratories, with exclusive rights to Sangretech’s dendritic cell technology in certain territories. [More]

Key defence mechanism used by the immune system against Listeria identified

6. October 2009 04:10
A team of University of British Columbia microbiologists has identified a key defence mechanism used by the immune system against Listeria with strong implications for the future development of vaccines. [More]

Reportlinker's medical review criteria guidelines for managing care

30. September 2009 08:03
Reportlinker Adds Medical Review Criteria Guidelines for Managing Care (8th ed. - 2009) [More]

Posted in: Healthcare News

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Illustrated guide on skin lymphoma

17. September 2009 05:42
Research and Markets (http://www.researchandmarkets.com/research/2fddd6/skin_lymphoma_the) has announced the addition of John Wiley and Sons Ltd's new report "Skin Lymphoma: The Illustrated Guide, 3rd Edition" to their offering. [More]

Posted in: Medical Condition News

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NCI-funded SPORE grant aims to improve kidney cancer treatment

16. September 2009 00:32
The National Cancer Institute (NCI) has awarded Beth Israel Deaconess Medical Center (BIDMC) an $11.5 million, five-year SPORE grant to focus on cancers of the kidney. Michael Atkins, MD, Deputy Director of BIDMC's Division of Hematology/Oncology, will oversee the grant, which involves collaborations with Brigham and Women's Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital via the Dana-Farber/Harvard Cancer Center. [More]

Posted in: Medical Condition News

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Celldex commences dosing patients in Phase 1/2 study of its CDX-1401 vaccine candidate

14. September 2009 09:57
Celldex Therapeutics, Inc. (NASDAQ: CLDX) today announced that the first patient has been dosed in a Phase 1/2 study of its vaccine candidate, CDX-1401, in patients with malignant solid tumors that express NY-ESO-1. CDX-1401 is a fully human monoclonal antibody designed to selectively deliver the NY-ESO-1 antigen to dendritic cells to generate a robust immune response against cancer cells expressing NY-ESO-1. [More]

Bellicum Pharmaceuticals starts phase I/II trial of novel advanced prostate cancer vaccine

6. August 2009 22:42
Bellicum Pharmaceuticals, Inc. today announced dosing of the first patient in a Phase I/II clinical trial of BP-GMAX-CD1, a novel pharmacologically regulated dendritic cell vaccine for the treatment of prostate cancer. The disease-specific trial is being conducted under a Bellicum Investigational New Drug application allowed by the FDA in 2008. The company anticipates reporting initial results of the study in 2010. [More]

Posted in: Drug Trial News

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Nanoparticle Trojan horse for ovarian cancer

19. July 2009 20:23
In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor. [More]

Posted in: Medical Research News

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Future of organ transplantation - microscopic beads that create "designer " immune cells

6. July 2009 20:33
Dr. Anatolij Horuzsko, Medical College of Georgia The future of organ transplantation could include microscopic beads that create "designer" immune cells to help patients tolerate their new organ, Medical College of Georgia researchers say. [More]

Posted in: Medical Research News

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Discovery in dendritic cell signalling pathways pave way for new therapeutic targets

15. June 2009 19:46
Scientists from A*STAR's Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells. This discovery was published in the advanced online publication of Nature on 15 Jun 2009. [More]

Posted in: Medical Research News

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