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Dengue (DF) and dengue hemorrhagic fever (DHF) are caused by one of four closely related, but antigenically distinct, virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4), of the genus Flavivirus. Infection with one of these serotypes provides immunity to only that serotype for life, so persons living in a dengue-endemic area can have more than one dengue infection during their lifetime. DF and DHF are primarily diseases of tropical and sub tropical areas, and the four different dengue serotypes are maintained in a cycle that involves humans and the Aedes mosquito. However, Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans, is the most common Aedes species. Infections produce a spectrum of clinical illness ranging from a nonspecific viral syndrome to severe and fatal hemorrhagic disease. Important risk factors for DHF include the strain of the infecting virus, as well as the age, and especially the prior dengue infection history of the patient.
Insect-borne diseases increase with warmer climate

Insect-borne diseases increase with warmer climate

Insects, such as mosquitoes and ticks, are responsible for transmitting a range of diseases, such as malaria, chikungunya, dengue fever, and West Nile virus. The risk of contracting such illnesses is generally only considered when booking an exotic holiday. However, experts from the Emergency Response Department at Public Health England have warned that climate change could allow such vector-borne diseases to emerge closer to home. [More]
Globavir, BioManguinhos partner to jointly evaluate PanGlob RT-PCR Dengue diagnostic assay

Globavir, BioManguinhos partner to jointly evaluate PanGlob RT-PCR Dengue diagnostic assay

Globavir Biosciences, Inc., a biotechnology company developing diagnostic and therapeutic technologies to treat infectious diseases, has announced a partnership with BioManguinhos, a division of the Oswaldo Cruz Foundation, for a joint evaluation of Globavir's PanGlob RT-PCR Dengue diagnostic assay. [More]
Climate change could accelerate emergence of vector-borne diseases in UK

Climate change could accelerate emergence of vector-borne diseases in UK

Climate change could accelerate the emergence of vector-borne diseases such as chikungunya, dengue fever, and West Nile virus in the UK, warn leading public health experts Dr Jolyon Medlock and Professor Steve Leach from the Emergency Response Department at Public Health England, writing in The Lancet Infectious Diseases journal. [More]
Virginia Tech researchers use genome-editing method to study lethal disease-carrying animal

Virginia Tech researchers use genome-editing method to study lethal disease-carrying animal

Life science researchers at Virginia Tech have accelerated a game-changing technology that's being used to study one of the planet's most lethal disease-carrying animals. [More]
Dengue fever circulating in urban areas of West Africa

Dengue fever circulating in urban areas of West Africa

Misdiagnosis of febrile illnesses as malaria is a continuing problem in Africa. A new study shows that in Ghana, dengue fever is circulating in urban areas and going undiagnosed. The authors of the study hope to use the findings to launch a widespread initiative to better understand acute undifferentiated febrile illnesses in West Africa. [More]
Modified measles vaccine effective against Chikungunya virus, study finds

Modified measles vaccine effective against Chikungunya virus, study finds

A modified, conventional measles vaccine has the potential to act against the Chikungunya virus. This is the result of a study at the University Clinic for Clinical Pharmacology of the MedUni Wien (Medical University of Vienna), which has now been published in the top journal "The Lancet Infectious Diseases". [More]
Simple paper strip test can rapidly diagnose Ebola

Simple paper strip test can rapidly diagnose Ebola

When diagnosing a case of Ebola, time is of the essence. However, existing diagnostic tests take at least a day or two to yield results, preventing health care workers from quickly determining whether a patient needs immediate treatment and isolation. [More]
Single genomic change can make beneficial bacteria into pathogenic bacteria

Single genomic change can make beneficial bacteria into pathogenic bacteria

We, as most animals, host many different beneficial bacteria. Being beneficial to the host often pays off for the bacteria, as success of the host determines the survival and spread of the microbe. But if bacteria grow too much they may become deadly. [More]
Research breakthrough in understanding mosquito reproductive process

Research breakthrough in understanding mosquito reproductive process

Diseases transmitted by mosquitoes have contributed to the death and suffering of millions throughout human history, earning the mosquito the title as the world's most dangerous animal. Even today, several devastating mosquito-borne diseases (such as malaria, dengue fever and West Nile virus) continue to rage. [More]
Potential new active substances for treating dengue virus

Potential new active substances for treating dengue virus

Researchers from Johannes Gutenberg University Mainz and the Julius Maximilian University of Würzburg are proposing potential new active substances for treating the dengue virus. Just like Ebola, dengue fever is also caused by a virus for which there is currently no cure and no vaccine and can be fatal. [More]
Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University and 60P Australia Pty Ltd, a subsidiary of 60° Pharmaceuticals LLC, have announced today an exclusive partnering deal, with 60P obtaining rights to develop the drug Fenretinide for dengue fever. [More]
Three-day global symposium on Ebola virus, other infectious diseases

Three-day global symposium on Ebola virus, other infectious diseases

The 11th annual International Consortium on Anti-Virals (ICAV) symposium, Infectious Diseases: Global Public-Health Challenges of the Next Decade, will put the challenges posed by several infectious diseases under the microscope, including the Ebola virus, the H7N9 influenza virus, MERS coronavirus and dengue viruses, as well as drug-resistant tuberculosis. [More]

Searching online for diagnosis before visiting doctor can predict dengue fever outbreaks in China

Queensland University of Technology researchers have found the habit of Googling for an online diagnosis before visiting the doctor can be a powerful predictor of infectious diseases outbreaks. [More]
Researchers find that yellow fever mosquitoes contain odor-detecting gene

Researchers find that yellow fever mosquitoes contain odor-detecting gene

One of the world's deadliest mosquitoes sustains its taste for human blood thanks in part to a genetic tweak that makes it more sensitive to human odor, according to new research. [More]
Ebola outbreak emphasizes the importance of monitoring disease burden in developing countries

Ebola outbreak emphasizes the importance of monitoring disease burden in developing countries

A study recently published in the Journal of the American Academy of Dermatology shows that for Ebola, measles, syphilis and many other conditions with skin manifestations the mortality rates are hundreds of times higher in developing countries than they are in developed countries. [More]
Dengue fever cases in India 282 times higher than officially reported, study says

Dengue fever cases in India 282 times higher than officially reported, study says

The annual number of dengue fever cases in India is 282 times higher than officially reported, and the disease inflicts an economic burden on the country of at least US$1.11 billion each year in medical and other expenses, according to a new study published online today in the American Journal of Tropical Medicine & Hygiene. [More]

Scientists analyze current situation of malaria and dengue fever in Himalayas

Research by Nepalese and German scientists from the Nepal Health Research Council, Goethe University and the LOEWE Biodiversity and Climate Research Centre analyzes the current situation of these diseases in the Himalayan country of Nepal and highlights how they profit from climate change and globalization. [More]
SLU researchers work to prevent several serious infectious diseases

SLU researchers work to prevent several serious infectious diseases

Saint Louis University researchers are attacking influenza on multiple fronts as they search for a universal vaccine that protects people from the flu virus that often mutates year to year with deadly consequences. [More]
Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Globavir Biosciences, Inc., a biotechnology company developing therapeutics to treat infectious diseases, has announced intentions to develop its lead drug candidate, GBV006, for the treatment of the current Ebola Virus outbreak in West Africa. Globavir will seek approval for the use of GBV006, a combination of Food and Drug Administration approved drugs, through an established compassionate use regulatory pathway. [More]
Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended June 30, 2014. Total revenue was $3.8 million and $6.2 million for the three and six months ended June 30, 2014, compared to $786,000 and $2.2 million for the same periods in 2013. [More]
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