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Dengue (DF) and dengue hemorrhagic fever (DHF) are caused by one of four closely related, but antigenically distinct, virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4), of the genus Flavivirus. Infection with one of these serotypes provides immunity to only that serotype for life, so persons living in a dengue-endemic area can have more than one dengue infection during their lifetime. DF and DHF are primarily diseases of tropical and sub tropical areas, and the four different dengue serotypes are maintained in a cycle that involves humans and the Aedes mosquito. However, Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans, is the most common Aedes species. Infections produce a spectrum of clinical illness ranging from a nonspecific viral syndrome to severe and fatal hemorrhagic disease. Important risk factors for DHF include the strain of the infecting virus, as well as the age, and especially the prior dengue infection history of the patient.
Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

As health departments around the U.S. boost efforts to combat Zika, scientists are working on new ways to kill the mosquitoes that carry the virus. One approach involves understanding the molecular mechanisms that keep the bugs alive so we can then undermine them. [More]
Mayo Clinic offers CDC’s Zika virus screening test

Mayo Clinic offers CDC’s Zika virus screening test

Mayo Clinic will offer the Zika virus antibody test developed by the Centers for Disease Control and Prevention. [More]
Study: Risk of sports fans catching dengue fever during Rio Olympics low

Study: Risk of sports fans catching dengue fever during Rio Olympics low

The risk of sports fans catching dengue fever during the Rio Olympics is very low, according to a new study involving mathematicians at the University of Strathclyde. [More]
New odour-baited traps offer effective and safe solution to fight against malaria mosquito

New odour-baited traps offer effective and safe solution to fight against malaria mosquito

The use of a newly-developed mosquito trap incorporating human odour has resulted in a 70% decline in the population of the most significant malaria mosquito on the Kenyan island of Rusinga. [More]
Scientists modeling new control mechanism to combat Zika-infecting mosquitoes

Scientists modeling new control mechanism to combat Zika-infecting mosquitoes

The images are heartbreaking: thousands of infants born with small, misshapen heads, the result of a rare neurological disorder, called microcephaly, which can cause a myriad of intellectual and developmental disabilities. The culprit? Zika, a mosquito-borne virus that has swept through many parts of South America and more recently surfaced in Florida. [More]
Novel crowdsourced disease surveillance tool may help fight against dengue

Novel crowdsourced disease surveillance tool may help fight against dengue

Brought to you by Break Dengue, Dengue Track is a novel approach to disease mapping which could also be used to tracking Zika virus or Malaria. [More]
OVC research may help improve cancer treatment

OVC research may help improve cancer treatment

Cancer treatment in people could be transformed thanks to a study on treating cancer in animals led by researchers from the Ontario Veterinary College at the University of Guelph. [More]
Scientists use machine learning to interpret mosquito genome

Scientists use machine learning to interpret mosquito genome

Scientists are using machine learning to identify important sequences of DNA within the mosquito genome that regulate how the insect's cells develop and behave. [More]
Telephone-based disease surveillance system can forecast dengue fever outbreaks

Telephone-based disease surveillance system can forecast dengue fever outbreaks

A team of scientists has developed a system that can forecast the outbreak of dengue fever by simply analyzing the calling behavior of citizens to a public-health hotline. [More]
Pre-existing dengue antibodies can intensify Zika virus infection

Pre-existing dengue antibodies can intensify Zika virus infection

Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London. [More]
Tackling Zika: are insect repellents the answer? An interview with Bruno Jactel

Tackling Zika: are insect repellents the answer? An interview with Bruno Jactel

The repellents that are used today are mostly based on what we call chemical pesticides. These products are used to repel mosquitoes as well as ticks. They are very broadly used, but there are different issues surrounding their use. [More]
Warming temperatures may increase risk for dengue outbreaks in Europe

Warming temperatures may increase risk for dengue outbreaks in Europe

Increasing temperatures will enlarge Europe's seasonal window for the potential spread of mosquito-borne viral disease, expanding the geographic areas at risk for a dengue epidemic to include much of Europe. The findings by researchers at Umea University in Sweden are published in the journal EBioMedicine. [More]
Research describes first new mouse model for Zika infection in decades

Research describes first new mouse model for Zika infection in decades

Efforts to combat the rapid spread of Zika virus got a boost this week as researchers at the University of Texas Medical Branch, Galveston (UTMB) announced the first peer-reviewed publication of a mouse model for Zika infection reported in decades. [More]
Biological change in mosquito mating could be used to fight mosquito-borne diseases

Biological change in mosquito mating could be used to fight mosquito-borne diseases

Genetic cues from male Aedes aegypti mosquitoes passed on during sex affect which genes are turned on or off in a females' reproductive tract post-mating, including genes related to blood feeding, egg development and immune defense, according to new Cornell research. [More]
Novel way proposed for developing infectious disease models to uncover hidden patterns of transmission

Novel way proposed for developing infectious disease models to uncover hidden patterns of transmission

Ebola. Chikungunya. Zika. Once rare and exotic pathogens keep popping up and turning into household names. It's the new reality as the climate warms, humans expand more into wildlife habitats and air travel shrinks the distances across the globe. [More]
WRAIR researchers publish results from Plasmodium vivax malaria vaccine study

WRAIR researchers publish results from Plasmodium vivax malaria vaccine study

Walter Reed Army Institute of Research researchers recently published the results of testing a Plasmodium vivax malaria vaccine candidate in a human challenge model. [More]
Zika virus can cross the placental barrier, according to new study

Zika virus can cross the placental barrier, according to new study

A study of pregnant women in Brazil has confirmed the presence of Zika virus in the amniotic fluid of two women who had displayed Zika-like symptoms during their pregnancies. [More]
ESCMID gathers more solid data to better assess Zika virus risks, prepares for possible outbreak in Africa, Europe

ESCMID gathers more solid data to better assess Zika virus risks, prepares for possible outbreak in Africa, Europe

Experts at the European Society of Clinical Microbiology and Infectious Diseases – an organization promoting research, risk assessment, knowledge sharing and best practices in the fight against infectious diseases – are developing tools to monitor the spread of the Zika virus and are conducting research to gather more solid data to better assess the risks associated with the infection. [More]

El Niño plays significant role in outbreak of haemorrhagic fevers

The dengue virus affects 390 million people globally every year, and fears are that early 2016 will see an epidemic, particularly in South-East Asia, due to the predicted extreme intensity of El Niño. A new study published in the Proceedings of the National Academy of Sciences has revealed the significant role that this monster climatic phenomenon plays in the outbreak of haemorrhagic fevers. [More]
Zika virus threat across the Americas

Zika virus threat across the Americas

Yesterday, the World Health Organization (WHO) announced that the Zika virus outbreak in Brazil was “spreading explosively” in the Americas and that as many as four million people could be infected by the end of the year. [More]
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