Diabetes Mellitus News and Research RSS Feed - Diabetes Mellitus News and Research

Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.
Heart rate measures could identify individuals with higher risk of diabetes

Heart rate measures could identify individuals with higher risk of diabetes

An association between resting heart rate and diabetes suggests that heart rate measures could identify individuals with a higher future risk of diabetes, according to an international team of researchers. [More]
Tandem Diabetes Care announces release of t:flex Insulin Pump

Tandem Diabetes Care announces release of t:flex Insulin Pump

Tandem Diabetes Care, Inc., a medical device company and manufacturer of the t:slim Insulin Pump, today announced that it is now taking orders for the t:flex Insulin Pump, with shipments planned to begin in June. The 480-unit t:flex Pump, cleared by the U.S. Food and Drug Administration in January 2015, is the largest capacity insulin pump currently offered in the United States. [More]
New Johns Hopkins-led research suggests risk factors for developing acute kidney injury

New Johns Hopkins-led research suggests risk factors for developing acute kidney injury

Physicians treating hospitalized patients for conditions unrelated to the kidneys should pay close attention to common blood and urine tests for kidney function in order to prevent incidental injury to the organs that help cleanse the body of toxins, new Johns Hopkins Bloomberg School of Public Health-led research suggests. [More]
Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics, Inc. today announced business and financial results for the first quarter ended March 31, 2015. [More]
Diabetic neuropathy highly prevalent among diabetic patients in Romania

Diabetic neuropathy highly prevalent among diabetic patients in Romania

A survey of 25,000 Romanians with diabetes has revealed that diabetic neuropathy (DN), a complication of diabetes, is highly prevalent in these patients, even in the absence of a diagnostic, and has an important impact on patients' quality of life. [More]
Resverlogix, Hepalink announce equity investment and license agreement for RVX-208

Resverlogix, Hepalink announce equity investment and license agreement for RVX-208

Resverlogix Corp. today announced that it has entered into a Framework Agreement which sets forth the principal business terms for an equity investment and a license of RVX-208, for all indications, to Shenzhen Hepalink Pharmaceutical Co., Ltd. for China, Hong Kong, Taiwan and Macau (the "Territories"). [More]
Study shows NASH linked to 50% higher death rates compared with NAFLD

Study shows NASH linked to 50% higher death rates compared with NAFLD

Results from a large population-based cohort of almost a million people in the UK found that the chances of dying from non-alcoholic steatohepatitis (NASH), over a 14-year period, was approximately 50% higher than for those with non-alcoholic fatty liver disease (NAFLD). [More]
Tandem Diabetes Care commences shipments of t:slim Insulin Pumps with enhanced software

Tandem Diabetes Care commences shipments of t:slim Insulin Pumps with enhanced software

Tandem Diabetes Care, Inc., a medical device company and manufacturer of the t:slim and t:flex Insulin Pumps, today commenced shipments of t:slim Pumps featuring enhanced software. [More]
CiRA, Takeda collaborate to develop clinical applications of iPS cells

CiRA, Takeda collaborate to develop clinical applications of iPS cells

Center for iPS Cell Research Application of Kyoto University and Takeda Pharmaceutical Company Limited announced today that they will work together to develop clinical applications of induced pluripotent stem cells in areas such as heart failure, diabetes mellitus, neurological disorders and cancer immunotherapy. [More]
Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai Inc. and Arena Pharmaceuticals, Inc. today announced the completion of two Phase 1 registrational clinical trials that Eisai and Arena believe demonstrate bioequivalence of an investigational once-daily extended release formulation of lorcaserin, as compared to the twice-daily immediate release formulation approved by the US Food and Drug Administration and marketed as BELVIQ. [More]
Astellas Pharma, MD Anderson sign option agreement to research and develop new treatment for AML

Astellas Pharma, MD Anderson sign option agreement to research and develop new treatment for AML

Astellas Pharma Inc. and The University of Texas MD Anderson Cancer Center today announced the signing of an option agreement to research and develop a new treatment for patients with acute myeloid leukemia (AML). [More]
New Quest Diagnostics study analyses impact of ACA in promoting earlier diagnosis of diabetes

New Quest Diagnostics study analyses impact of ACA in promoting earlier diagnosis of diabetes

People in states that expanded Medicaid under the Affordable Care Act (ACA) are far more likely to be newly identified with diabetes than in states that elected not to expand the public health care program, finds a new study by researchers at Quest Diagnostics. [More]
Active ingredient dextromethorphan may help people with Type 2 diabetes

Active ingredient dextromethorphan may help people with Type 2 diabetes

The active ingredient dextromethorphan, which is contained in many over-the-counter cough remedies, has been shown to improve blood sugar levels in type 2 diabetes (diabetes mellitus). That was the finding of a recent international study, in which the Center for Physiology and Pharmacology of MedUni Vienna played a significant part and which has now been published in the leading medical journal "Nature Medicine". [More]
Researchers gain new insights into molecular mechanisms affected by weight gain

Researchers gain new insights into molecular mechanisms affected by weight gain

Until now there have been few molecular epidemiological studies regarding the effects of weight changes on metabolism in the general population. In a recent study conducted and funded within the framework of the Competence Network Obesity, researchers at the Institute of Epidemiology II at Helmholtz Zentrum München evaluated molecular data of the KORA study. [More]
TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Pharmaceuticals, Inc. today announced that its fully owned subsidiary, TWi Biotechnology, Inc., has received the designation of Rare Disease Drug by Taiwan FDA for use of AC-203 to treat Epidermolysis Bullosa Simplex (EBS), and is eligible for applying for coverage under National Health Insurance Administration. [More]
New study finds that fetus exposed to tobacco smoke faces diabetes risk in adulthood

New study finds that fetus exposed to tobacco smoke faces diabetes risk in adulthood

A fetus exposed to tobacco smoke may be at increased risk for diabetes in adulthood, a new study of adult daughters finds. [More]
Obese females with eating/behavioral characteristic have impaired metabolism

Obese females with eating/behavioral characteristic have impaired metabolism

In obese females, a close relationship may exist between their disinhibition (detrimental eating and behavioral characteristics) that limits successful weight loss, and impaired metabolism, new research shows. [More]
Even 30 minutes of sleep debt per day can promote obesity and insulin resistance

Even 30 minutes of sleep debt per day can promote obesity and insulin resistance

Losing as little as 30 minutes of sleep per day on weekdays can have long-term consequences for body weight and metabolism, a new study finds. The results will be presented Thursday, March 5, at ENDO 2015, the annual meeting of the Endocrine Society in San Diego. [More]
Sleep apnea prevalent in obese, pregnant Asian women with gestational diabetes

Sleep apnea prevalent in obese, pregnant Asian women with gestational diabetes

Obstructive sleep apnea (OSA) is prevalent in obese, pregnant Asian women with gestational diabetes, even when their diabetes is controlled by diet, a new study from Thailand finds. [More]
Academy of Nutrition and Dietetics highlights positive effects of human milk on infants, maternal health

Academy of Nutrition and Dietetics highlights positive effects of human milk on infants, maternal health

Human milk provides the best nutrition for most babies and breastfeeding provides the best nutrition for infants and very young children, according to an updated position paper from the Academy of Nutrition and Dietetics. [More]
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