Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.

Further Reading

Antibiotic resistance: a healthcare emergency?

Antibiotic resistance: a healthcare emergency?

Self-monitoring of blood glucose in patients with T2DM did not improve glycemic control after one year

Self-monitoring of blood glucose in patients with T2DM did not improve glycemic control after one year

Study shows benefits of CGM in adults with diabetes who take multiple daily injections

Study shows benefits of CGM in adults with diabetes who take multiple daily injections

Researchers discover molecular signaling circuit that regulates autophagy

Researchers discover molecular signaling circuit that regulates autophagy

British Society for Rheumatology releases updated clinical guideline for gout management

British Society for Rheumatology releases updated clinical guideline for gout management

Study finds link between type 1 diabetes and increased risk of bone fractures in men

Study finds link between type 1 diabetes and increased risk of bone fractures in men

Researchers find direct link between outdoor temperature and risk of gestational diabetes

Researchers find direct link between outdoor temperature and risk of gestational diabetes

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

Two widely used drugs show effectiveness in treating patients with CRVO-associated macular edema

Two widely used drugs show effectiveness in treating patients with CRVO-associated macular edema

Newly-developed smart contact lens sensor may help diagnose diabetes and glaucoma

Newly-developed smart contact lens sensor may help diagnose diabetes and glaucoma

Glycated CD59 identified as novel biomarker for screening and diagnosis of gestational diabetes

Glycated CD59 identified as novel biomarker for screening and diagnosis of gestational diabetes

Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases

Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases

Study describes synthesis and biological evaluation of novel, effective ARIs

Study describes synthesis and biological evaluation of novel, effective ARIs

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

World's leading heart failure congress sets new record for abstract submissions

World's leading heart failure congress sets new record for abstract submissions

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

TUM scientists show how diabetes damages small blood vessels around the heart

TUM scientists show how diabetes damages small blood vessels around the heart

New approach shows promise to prevent, treat cholesterol gallstone disease

New approach shows promise to prevent, treat cholesterol gallstone disease

FDA approves new nasal spray for adults who overproduce urine at night

FDA approves new nasal spray for adults who overproduce urine at night