Diabetes Mellitus News and Research RSS Feed - Diabetes Mellitus News and Research

Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.
New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

Various active substances in oral antidiabetic agents are frequently combined in the treatment of diabetes in order to achieve an effective reduction in the blood sugar. A new, very promising approach combines the substances metformin and SGLT2 inhibitors, the latter were just approved in 2012. [More]
Diabetes linked to increased head and neck cancer risk

Diabetes linked to increased head and neck cancer risk

People with diabetes mellitus have a significantly increased risk of developing head and neck cancer compared with those without the condition, show results of a large study conducted in Taiwan. [More]
New hope for people suffering from obesity and diabetes

New hope for people suffering from obesity and diabetes

White, brown and beige adipocytes, or fat cells, are inherently different. Each of these cell types has different functions and each plays its own role in metabolism. In the human body, white adipose tissue is by far the most prevalent. [More]
EMA CHMP issues positive opinion for label updates to Takeda's Vipidia, Vipdomet and Incresync

EMA CHMP issues positive opinion for label updates to Takeda's Vipidia, Vipdomet and Incresync

Takeda Pharmaceuticals International GmbH today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has issued positive opinions for updates to the Summary of Product Characteristics (SmPC) for Vipidia (alogliptin) and the fixed-dose combination (FDC) therapies Vipdomet (alogliptin and metformin) and Incresync (alogliptin and pioglitazone). [More]
GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

GSK today announced that once-weekly Tanzeum (albiglutide), a prescription injectable treatment for type 2 diabetes in adults, as an adjunct to diet and exercise, is now available in pharmacies throughout the U.S. [More]
Study: L-carnitine has neuroprotective effects on injured sciatic nerve of rats

Study: L-carnitine has neuroprotective effects on injured sciatic nerve of rats

Several studies have demonstrated that L-carnitine exhibits neuroprotective effects on injured sciatic nerve of rats with diabetes mellitus. [More]
New analysis reveals 40% decrease in incidence of stroke in older Medicare patients

New analysis reveals 40% decrease in incidence of stroke in older Medicare patients

Rates Declined for Ischemic and Hemorrhagic Stroke and Mortality in Both Men and Women 65 Years and Older, Reports The American Journal of Medicine [More]
Night-time BP variability improves vascular risk prediction

Night-time BP variability improves vascular risk prediction

Measuring night-time variability in the blood pressure of patients with hypertension may help to predict their risk of having a cardiovascular event, show data from an international study. [More]
Physical fitness may buffer some of adverse health effects of too much sitting

Physical fitness may buffer some of adverse health effects of too much sitting

Physical fitness may buffer some of the adverse health effects of too much sitting, according to a new study by researchers from the American Cancer Society, The Cooper Institute, and the University of Texas. [More]
Portable, microchip-based test for diagnosing type-1 diabetes

Portable, microchip-based test for diagnosing type-1 diabetes

An inexpensive, portable, microchip-based test for diagnosing type-1 diabetes could improve patient care worldwide and help researchers better understand the disease, according to the device's inventors at the Stanford University School of Medicine. [More]
Afrezza gets FDA approval to improve glycemic control in adults with diabetes mellitus

Afrezza gets FDA approval to improve glycemic control in adults with diabetes mellitus

The U.S. Food and Drug Administration today approved Afrezza (insulin human) Inhalation Powder, a rapid-acting inhaled insulin to improve glycemic control in adults with diabetes mellitus. Afrezza is a rapid-acting inhaled insulin that is administered at the beginning of each meal, or within 20 minutes after starting a meal. [More]
Women who develop gestational diabetes perform worse on cognitive function tests

Women who develop gestational diabetes perform worse on cognitive function tests

Women who develop diabetes during pregnancy, called gestational diabetes, perform worse on cognitive function tests than do women with a normal pregnancy, according to a new study from Turkey. [More]
Researchers identify six gene loci associated with pulmonary diseases

Researchers identify six gene loci associated with pulmonary diseases

In their investigations or so-called genome-wide association studies, the team of researchers compared the genetic profile of study participants to the forced vital capacity (FVC), a volume parameter of lung function. [More]
No link between consumption of cow's milk-based formula and development of autoantibodies in kids

No link between consumption of cow's milk-based formula and development of autoantibodies in kids

There is no correlation between the consumption of a cow's milk-based formula or hydrolyzed protein formula and the development of diabetes-associated autoantibodies in children younger than seven, according to a worldwide research study published in the Journal of the American Medical Association (JAMA). [More]
New app for smartphones automatically calculates carbohydrate content of meal

New app for smartphones automatically calculates carbohydrate content of meal

An app for smartphones automatically calculates the carbohydrate content of a meal. The programme called "GoCARB" enables diabetics to better plan their meals and to control their blood glucose easier. [More]
Researchers emphasize critical need to utilize multi-pronged approach to treat diabetes mellitus

Researchers emphasize critical need to utilize multi-pronged approach to treat diabetes mellitus

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University; Marc A. Pfeffer, M.D., Dzau professor of medicine at Harvard Medical School; John W. Newcomer, M.D., executive vice dean of FAU's College of Medicine and interim vice president for research at FAU; Paul S. Jellinger, M.D., affiliate professor at the University of Miami Miller School of Medicine; and Alan Garber, M.D., Ph.D., professor of medicine at Baylor, have published a commentary in the American Journal of Managed Care titled "Treatment of Diabetes Mellitus: The Urgent Need for Multifactorial Interventions." [More]
Patients with diabetes mellitus have worse long-term outcomes following CABG surgery

Patients with diabetes mellitus have worse long-term outcomes following CABG surgery

Patients with diabetes mellitus have worse long-term outcomes and higher associated costs following coronary artery bypass grafting (CABG) surgery than patients without diabetes, according to a study in the June 2014 issue of The Annals of Thoracic Surgery. [More]
Contemporary dataset reveals burden of paediatric pneumococcal disease

Contemporary dataset reveals burden of paediatric pneumococcal disease

Children with chronic or immunocompromising medical conditions continue to be at increased risk for developing pneumococcal disease in the current era of universal immunisation, US researchers report. [More]
Intensive insulin has lasting benefits for diabetic MI survivors

Intensive insulin has lasting benefits for diabetic MI survivors

Patients with diabetes given intensive insulin treatment following an acute myocardial infarction had improved survival over 20 years of follow-up of the DIGAMI 1 trial, report the investigators. [More]
Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Epilepsy is a group of neurological disorders often characterized by seizures and cognitive impairment due to electrical disturbances in the brain. [More]