Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.

Further Reading

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

Results of high-impact clinical trials could improve kidney-related medical care

Results of high-impact clinical trials could improve kidney-related medical care

Study finds link between hypoglycemia and mortality risk in hospitalized patients

Study finds link between hypoglycemia and mortality risk in hospitalized patients

Study finds link between winter conception and gestational diabetes risk

Study finds link between winter conception and gestational diabetes risk

Scientists discover new mechanism responsible for regulation of glucose metabolism

Scientists discover new mechanism responsible for regulation of glucose metabolism

Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

Targeted precision medicine can eliminate cancer risk in patients with Type 2 diabetes

Study assesses impact of diabetes mellitus on cardiac geometry

Study assesses impact of diabetes mellitus on cardiac geometry

Regular physical activity is good, but more is better to reduce risk of type 2 diabetes

Regular physical activity is good, but more is better to reduce risk of type 2 diabetes

Research findings raise hope for better treatment of diabetic wounds

Research findings raise hope for better treatment of diabetic wounds

New review shows both types of diabetes increase risk of fragility fractures

New review shows both types of diabetes increase risk of fragility fractures

GACD funds international research projects that aim to prevent, manage chronic lung diseases

GACD funds international research projects that aim to prevent, manage chronic lung diseases

Individuals with BED may experience broad array of physical illnesses, study reveals

Individuals with BED may experience broad array of physical illnesses, study reveals

Improving muscle health could enhance response to insulin in Type 1 diabetes patients

Improving muscle health could enhance response to insulin in Type 1 diabetes patients

Oral antidiabetic drug modulates the body's nitrogen and urea metabolism

Oral antidiabetic drug modulates the body's nitrogen and urea metabolism

Study reveals risk factors and outcomes of infective endocarditis after TAVR

Study reveals risk factors and outcomes of infective endocarditis after TAVR

Exposure to air pollution at place of residence could be risk factor for type 2 diabetes

Exposure to air pollution at place of residence could be risk factor for type 2 diabetes

Alcohol-related hospitalisation linked to increased risk of ischaemic stroke in atrial fibrillation patients

Alcohol-related hospitalisation linked to increased risk of ischaemic stroke in atrial fibrillation patients

Western dietary pattern linked to risk of developing Alzheimer's disease

Western dietary pattern linked to risk of developing Alzheimer's disease

Maternal GDM linked to increased risk of childhood obesity among children aged 9-11 years

Maternal GDM linked to increased risk of childhood obesity among children aged 9-11 years

Study shows overall prevalence of diabetic kidney disease remains unchanged among U.S. adults

Study shows overall prevalence of diabetic kidney disease remains unchanged among U.S. adults