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Diarrhea is loose, watery stools. A person with diarrhea typically passes stool more than three times a day. People with diarrhea may pass more than a quart of stool a day. Acute diarrhea is a common problem that usually lasts 1 or 2 days and goes away on its own without special treatment. Prolonged diarrhea persisting for more than 2 days may be a sign of a more serious problem and poses the risk of dehydration. Chronic diarrhea may be a feature of a chronic disease.

Diarrhea can cause dehydration, which means the body lacks enough fluid to function properly. Dehydration is particularly dangerous in children and older people, and it must be treated promptly to avoid serious health problems.

UNICEF report highlights gains in child health, while 1b still lack essential services

20. November 2009 23:47
A special edition of UNICEF's annual State of the World's Children report, released 20 years after the U.N. Convention on the Rights of the Child, shows that "fewer youngsters are dying and more are going to school - but an estimated 1 billion still lack services essential to their survival and development," the Associated Press reports. [More]

Posted in: Child Health News | Disease/Infection News

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"EurSafety Health-net" launched to fight hospital acquired MRSA infection

20. November 2009 03:34
On November 19, 2009, the kick-off meeting for the Euregio-project "EurSafety Health-net" has taken place. EurSafety Health-net is the follow-up of EUREGIO MRSA-net, that, according to the Robert Koch Institute, gained some sort of model character all over the nation when talking about prevention of hospital acquired MRSA infection. Besides the protection against infection, the main goal of this new project is to strengthen the patients' safety on both sides of the border. [More]

Posted in: Disease/Infection News

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Swissmedic grants marketing authorization for Amitiza

20. November 2009 00:59
Sucampo Pharma Europe Ltd., a subsidiary of Sucampo Pharmaceuticals, Inc., today announced that Swissmedic, the Swiss Agency for Therapeutic Products, has granted a marketing authorization for Amitiza® (lubiprostone) 24 microgram (mcg) gel capsules for the long-term treatment of patients with chronic idiopathic constipation (CIC). [More]

Posted in: Pharmaceutical News

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High prevalence of asthma among children with H1N1

19. November 2009 22:55
A new study on pediatric H1N1 influenza admissions has found that asthma is a significant risk factor for severe disease in children with pandemic H1N1 compared with the seasonal flu. [More]

Posted in: Child Health News | Medical Condition News | Disease/Infection News

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Xeomin receives approval for post-stroke spasticity of upper limb in European countries

19. November 2009 01:42
Today, Merz Pharmaceuticals announced Xeomin®, the first botulinum toxin type A free from complexing proteins has been granted an extension of indication for post-stroke spasticity of the upper limb presenting with flexed wrist and clenched fist in adults in various European countries. [More]

Interim data from an ongoing phase 1 dose-escalation trial of XL147 reported

19. November 2009 00:22
Exelixis, Inc. today reported interim data from an ongoing phase 1 dose-escalation trial of XL147 (SAR245408) in combination with the EGFR inhibitor erlotinib in patients with advanced solid tumors. [More]

Millennium commences Phase I clinical trial for its second-generation proteasome inhibitor

18. November 2009 10:31
Millennium: The Takeda Oncology Company today announced it has further expanded its protein homeostasis program with the initiation of a Phase I clinical trial for an oral formulation of MLN9708, the Company’s second-generation proteasome inhibitor. An intravenous formulation of MLN9708 entered clinical trials in March. [More]

New source of information can help prescribers and patients in understanding anticipated side effects of treatments

18. November 2009 06:35
In clinical trials for cancer, it is standard for clinicians rather than patients to report adverse symptom side effects from treatments, such as nausea and fatigue. At present, patient self-reporting, although important, is not a well studied source of this information. [More]

Posted in: Healthcare News

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Pediatric data for Pfizer's Lipitor submitted to the EMEA

18. November 2009 04:58
Pfizer Inc announced it has submitted pediatric data for Lipitor® (atorvastatin) to the European Medicines Agency (EMEA). Pfizer has also developed a new chewable form of Lipitor, including a pediatric-appropriate 5 mg dose, which is part of this submission. [More]

NeoPharm presents LE-DT Phase I data at the AACR conference

18. November 2009 04:30
NeoPharm, Inc. today announced the results of a Phase I clinical trial of Liposome Encapsulated Docetaxel (LE-DT) an active component of Taxotere® at a joint International Conference of the American Association for Cancer Research (AACR), the National Cancer Institute (NCI) and the European Organization for Research and Treatment of Cancer (EORTC) being held in Boston, MA. [More]

Ongoing Phase 1 study results of XMT-1001 announced by Mersana Therapeutics

18. November 2009 00:56
Mersana Therapeutics, a platform-based cancer therapeutics company, announced today additional preliminary results from an ongoing Phase 1 study of its lead development candidate, XMT-1001, in patients with advanced solid tumors. [More]

Posted in: Drug Trial News | Pharmaceutical News

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Report calls for refocusing health spending in developing countries to save children's lives

17. November 2009 23:57
"More than 24,000 infants die daily from preventable diseases in developing countries," and child deaths have fallen in countries where governments "have shown a high level of political leadership on child health," World Vision International said in a new report (.pdf) released on Monday as part of a five-year campaign to reduce child deaths worldwide, the Associated Press/San Francisco Chronicle reports. [More]

Posted in: Child Health News | Healthcare News

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AACR-NCI-EORTC conference highlights major expansion in cancer drug pipeline

17. November 2009 05:02
To highlight results of more recent research, the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics International Conference will host a press briefing on "Drugs in the Pipeline." Sara A. Courtneidge, Ph.D., D.Sc., professor and director of the Tumor Microenvironment Program, and director of academic affairs at the Burnham Institute for Medical Research, will moderate this press briefing. [More]

Genentech submits sBLAs to the FDA for Avastin

17. November 2009 03:36
Genentech, Inc., a wholly-owned member of the Roche Group, today announced that the company submitted two supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration (FDA) for Avastin® (bevacizumab) for the treatment of women who have not received chemotherapy for advanced (metastatic) HER2-negative breast cancer (first-line treatment). One sBLA is based on the Phase III study AVADO that investigated Avastin in combination with docetaxel chemotherapy. [More]

PPD, Janssen Pharmaceutica to develop therapeutic compounds for IBS and bacterial infections

17. November 2009 01:35
PPD, Inc. today announced it has entered an agreement with Janssen Pharmaceutica N.V. to develop and commercialize two Phase II-ready therapeutic compounds, one to treat diarrhea-predominant irritable bowel syndrome (IBS-d) and the other to treat complicated skin and skin structure and respiratory infections. [More]
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