Diastolic Dysfunction News and Research

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Diastolic dysfunction refers to an abnormality in the heart's (''i.e.'', left ventricle's) filling during diastole. Diastole is that phase of the cardiac cycle when the heart (i.e. ventricle) is not contracting but is actually relaxed and filling with blood that is being returned to it, either from the body (into right ventricle) or from the lungs (into left ventricle).

Increased coronary vessel wall thickness linked to heart dysfunction in asymptomatic HIV patients

A new study found increased coronary vessel wall thickness that was significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV.

4 Apr 2024

Increased cholesterol levels in adolescence linked to early heart damage

Heart disease is the number one killer disease in the world. Elevated cholesterol and dyslipidaemia in children and adolescents increase the risk of premature death in the mid-forties and subclinical atherosclerosis in the mid-twenties.

13 Jan 2024

Study reveals subclinical cardiac changes in Hispanic women with history of hypertensive pregnancy disorders

The long-term cardiac effects of de novo hypertensive disorders of pregnancy.

6 Dec 2023

Is obesity an independent risk factor for cardiovascular disease?

Researchers explore how obesity contributes to cardiovascular disease by investigating this association in low-risk people.

10 Nov 2023

Hormones and high blood pressure: Study reveals endocrine culprits and targeted treatments

Researchers delve into endocrine causes of hypertension (HTN), revealing key culprits like primary aldosteronism and Cushing's syndrome. The study also evaluates the efficacy of various treatments, offering valuable insights for tackling this widespread health issue.

15 Oct 2023

Study shows arterial stiffness as a novel cause of premature heart damage among adolescents

Arterial stiffness is a novel cause of premature heart damage among adolescents, according to a new follow-up study.

16 Aug 2023

The association of ambient air pollution and abnormal left ventricular diastolic function

Study investigated the associations between abnormal left ventricular diastolic function (ALVDF) and ambient air pollution.

16 Aug 2023

Elevated blood pressure linked to worsening cardiac damage during adolescence

Elevated blood pressure and hypertension can cause early cardiac damage during adolescence which is worsened by young adulthood, a paper published in the Journal of Pediatrics concludes.

8 Mar 2023

CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue -; a process known as cardiac fibrosis.

6 Jan 2023

Reduced cardiac function identified in severe COVID-19 patients in new study

In a new study, researchers assessed the cardiac function in patients experiencing severe coronavirus disease 2019 (COVID-19).

17 Oct 2022

How does COVID-19 affect arrythmia?

Researchers have been investigating the reports of cardiac damage in COVID-19 patients, and trying to determine if autoimmune effects could play a role.

10 Mar 2022

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death.

16 Sep 2021

Researchers receive $1,894,271 grant to address new drug targets for diastolic dysfunction

After the left ventricle of the heart contracts, it must relax efficiently to prepare to refill and supply the body with blood on the next beat. An increasing number of patients -- including nearly all patients with heart failure -- suffer from impaired relaxation, which is part of a clinical syndrome known as diastolic dysfunction. Currently, treatments for impaired relaxation do not exist.

12 Feb 2021

Study identifies cardiac structural damage experienced by COVID-19 patients

Cardiac ultrasounds (also known as echocardiograms) are providing a view of the heart and the impact of the COVID-19 virus on patients.

27 Oct 2020

Study finds cardiac involvement in MIS-C is associated with myocardial injury

Using sensitive parameters to assess cardiac function, researchers at Children's Hospital of Philadelphia (CHOP) have found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) differs from Kawasaki disease (KD) and is associated with myocardial injury.

21 Sep 2020

Rehabilitation speeds coronavirus recovery

Now, a team of researchers at the University Clinic in Innsbruck in Austria has found that the long-term lung and heart damage in coronavirus disease (COVID-19) patients who recovered tend to improve over time.

7 Sep 2020

Reductive stress is intolerable, can induce heart failure

Many heart diseases are linked to oxidative stress, an overabundance of reactive oxygen species. The body reacts to reduce oxidative stress -- where the redox teeter-totter has gone too far up -- through production of endogenous antioxidants that reduce the reactive oxygen species.

14 May 2020

Diastolic dysfunction associated with increased risk for arrhythmic death

Sudden cardiac death is a common cause of death in patients with reduced systolic ejection function. As part of a long-term observational study, MedUni Vienna researchers from the Division of Cardiology have now shown the importance of the diastolic filling function: the less the heart fills when there is diastolic dysfunction, the more likely patients are to die suddenly of cardiac arrhythmia.

11 May 2020

Heart size of dogs affects both vortex flow and pressure difference

An international collaboration led by veterinary scientists at Tokyo University of Agriculture and Technology, Japan, has found that size of a dog heart affects both vortex flow and pressure difference in the heart, which both are promising as an index of diastolic function.

27 Mar 2020

Research identifies link between chronic kidney disease and heart failure

People with chronic kidney disease have a higher risk for heart disease and heart-disease death. Now, for the first time in humans, research led by Navkaranbir Bajaj, M.D., of the University of Alabama at Birmingham, has identified a pathological change that appears to link kidney disease to progressive heart disease.

3 Feb 2020