Drug Delivery News and Research RSS Feed - Drug Delivery News and Research

Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.
New inexpensive technology can effectively sterilise medical implants

New inexpensive technology can effectively sterilise medical implants

International researchers led by the University of Bath have demonstrated a cheap, effective and environmentally-friendly way to sterilise medical implants without changing their properties, in contrast to some techniques. [More]
Nocturnal hypoxemia closely linked to diabetic microvascular complications

Nocturnal hypoxemia closely linked to diabetic microvascular complications

Examining the poorly understood link between obstructive sleep apnea (OSA) and type 2 diabetes complications, researchers identified specific measures of low blood oxygenation that are associated with impaired kidney function and diabetic nephropathy. [More]
Scientists derive first molecular model of critical transporter at blood-brain barrier

Scientists derive first molecular model of critical transporter at blood-brain barrier

Scientists from Duke-NUS Medical School have derived a structural model of a transporter at the blood-brain barrier called Mfsd2a. This is the first molecular model of this critical transporter, and could prove important for the development of therapeutic agents that need to be delivered to the brain --- across the blood-brain barrier. In future, this could help treat neurological disorders such as glioblastoma. [More]
Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

A collaborative Brigham and Women's Hospital and Johns Hopkins University co-led team has found proof-of-concept evidence for a potential cancer treatment that leverages microparticles and mesenchymal stem cells. [More]
Scientists develop innovative technique to deliver cancer drugs deep into tumour cells

Scientists develop innovative technique to deliver cancer drugs deep into tumour cells

Scientists at Nanyang Technological University (NTU Singapore) have invented a new way to deliver cancer drugs deep into tumour cells. [More]
Newly developed implantable device can deliver chemotherapy drugs directly to pancreatic tumors

Newly developed implantable device can deliver chemotherapy drugs directly to pancreatic tumors

Pancreatic cancer is the third leading cause of cancer deaths in the United States, in part because it is very difficult for chemotherapy drugs to reach the pancreas, which is located deep within the abdomen. [More]
Cornell researchers discover potential way to penetrate blood brain barrier

Cornell researchers discover potential way to penetrate blood brain barrier

Cornell researchers have discovered a way to penetrate the blood brain barrier (BBB) that may soon permit delivery of drugs directly into the brain to treat disorders such as Alzheimer's disease and chemotherapy-resistant cancers. [More]
Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

For more than a decade, biomedical researchers have been looking for better ways to deliver cancer-killing medication directly to tumors in the body. Tiny capsules, called nanoparticles, are now being used to transport chemotherapy medicine through the bloodstream, to the doorstep of cancerous tumors. [More]
New extended-release pills could reduce dosage frequency of some drugs

New extended-release pills could reduce dosage frequency of some drugs

Researchers from MIT and Brigham and Women's Hospital have designed a new type of pill that, once swallowed, can attach to the lining of the gastrointestinal tract and slowly release its contents. The tablet is engineered so that one side adheres to tissue, while the other repels food and liquids that would otherwise pull it away from the attachment site. [More]
Researchers develop new technique to study blood vessel inflammation

Researchers develop new technique to study blood vessel inflammation

Nanotechnology has led to better diagnostic techniques and more effective treatments for a variety of illnesses. Tiny devices measuring between 1 and 100 micrometers--one micrometer is equal to one millionth of a meter--enable scientists to observe cell activity and deliver drugs to individual cells--a breakthrough that is on the verge of revolutionizing precision medicine for treatment of diseases such as cancer. [More]
TSRI study shows hollowed-out version of CPMV could be effective in human therapies

TSRI study shows hollowed-out version of CPMV could be effective in human therapies

Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good—modifying the viruses to carry drug molecules, for example. [More]
Researchers demonstrate novel method for imaging engineered nanoparticles in tissues

Researchers demonstrate novel method for imaging engineered nanoparticles in tissues

As a testament to Governor Andrew Cuomo’s leadership in developing an unparalleled research and development ecosystem in New York State, Sara Brenner, MD, MPH and her colleagues at SUNY Polytechnic Institute (SUNY Poly), the George Washington School of Medicine and Health Sciences, and Stony Brook University have demonstrated a novel method for the rapid visualization and identification of engineered nanoparticles in tissues. [More]
Med-Tech Innovation Expo 2016 taking place on 20-21 April

Med-Tech Innovation Expo 2016 taking place on 20-21 April

Med-Tech Innovation Expo, the UK’s only Med-Tech event that is 100% dedicated to the design, innovation and manufacture of medical devices, is taking place on the 20-21 April at the Ricoh Arena, Coventry. [More]
Halozyme Therapeutics doses first patient in Halo-301 | Pancreatic study

Halozyme Therapeutics doses first patient in Halo-301 | Pancreatic study

Halozyme Therapeutics, Inc., a biotechnology company developing novel oncology and drug-delivery therapies, today announced the first patient has been dosed in its Halo-301 | Pancreatic study, a Phase 3 clinical trial in previously untreated metastatic pancreatic cancer patients. [More]
Research confirms potential use of iron oxide nanoparticles in biomedical applications

Research confirms potential use of iron oxide nanoparticles in biomedical applications

Iron oxides are widespread in nature and can be readily synthesized in the laboratory. Among them, hematite, magnetite and maghemite nanoparticles have particularly promising properties for biomedical applications. [More]

Theoretical modelling helps to understand interior structures of cubosomes

Under certain conditions appropriately selected particles can form closed surfaces in liquids with surprisingly complex shapes, cutting through space by a regular network of channels. So far, we have looked at cubosomes - for this is what these spectacular three-dimensional nanostructures are called - only from the outside. [More]
New drug could transform treatment of metastatic triple negative breast cancer

New drug could transform treatment of metastatic triple negative breast cancer

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice. [More]
Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Researchers report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the journal Small Molecule Therapeutics in February 2016. [More]
Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs. [More]
Research reviews importance of blood-brain barrier, blood-tumor barrier in treatment of brain tumors

Research reviews importance of blood-brain barrier, blood-tumor barrier in treatment of brain tumors

The research thoroughly reviews the importance of the blood-brain barrier (BBB) and the blood-tumor barrier (BTB) along with the current status and future perspectives of interesting physical and surgical strategies to circumvent these central nervous system (CNS) barriers in the treatment of malignant brain tumors. [More]
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