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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.
Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Researchers report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the journal Small Molecule Therapeutics in February 2016. [More]
Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs. [More]
Research reviews importance of blood-brain barrier, blood-tumor barrier in treatment of brain tumors

Research reviews importance of blood-brain barrier, blood-tumor barrier in treatment of brain tumors

The research thoroughly reviews the importance of the blood-brain barrier (BBB) and the blood-tumor barrier (BTB) along with the current status and future perspectives of interesting physical and surgical strategies to circumvent these central nervous system (CNS) barriers in the treatment of malignant brain tumors. [More]
CWRU researcher to customize tobacco mosaic virus to treat human cancers

CWRU researcher to customize tobacco mosaic virus to treat human cancers

A Case Western Reserve University researcher has been awarded more than $3 million in federal and foundation grants to turn common plant viruses into cancer sleuths and search-and-destroy emissaries. [More]
Drug-incorporated nanoparticle platforms allow for selective targeting of cancer cells

Drug-incorporated nanoparticle platforms allow for selective targeting of cancer cells

Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. It is a leading cause of death and the burden is expected to grow worldwide due to the growth and aging of the population, mainly in less developed countries, in which about 82% of the world's population resides. By 2030, the global burden is expected to grow to 21.7 million new cancer cases and 13 million cancer deaths simply due to the growth and aging of the population. Current cancer therapy approaches are based in surgery, radiotherapy and chemotherapy, being the chemotherapy the one that shows the greater efficiency for cancer treatment, mainly in more advanced stages. A major problem with this conventional chemotherapy is its toxicity and it also destroys healthy tissues resulting in systemic toxicity besides beneficial characteristics of killing cancer cells. Anticancer drugs also destroy healthy tissues resulting in systemic toxicity. [More]
Preceyes, Nightstar partner to develop drug delivery technology for ocular surgery

Preceyes, Nightstar partner to develop drug delivery technology for ocular surgery

Preceyes B.V. (NL) and Nightstar (UK) have entered into a collaboration for the development of a high-precision drug delivery technology in the eye. Nightstar will use the Preceyes robotic device to further refine the delivery of gene therapy to the subretinal space for a range of inherited retinal diseases. [More]
Insulet partners with Mode AGC to develop OmniPod Artificial Pancreas system

Insulet partners with Mode AGC to develop OmniPod Artificial Pancreas system

Insulet Corporation, the leader in tubeless insulin pump technology with its OmniPod Insulin Management System (OmniPod System), today announced a license agreement and partnership with Mode AGC (Automated Glucose Control LLC), to develop and incorporate the advanced artificial pancreas algorithm created by renowned researchers Francis Doyle PhD, Eyal Dassau PhD, and Howard Zisser MD. [More]
PolyPid closes $22 million private equity financing

PolyPid closes $22 million private equity financing

PolyPid Ltd., an emerging clinical-stage specialty pharmaceutical company, focused primarily on the development of post-surgical anti-infection pipeline, announced today that it closed a $22 million private equity financing. [More]
Ohio State researchers working on new way to treat drug-resistant cancer

Ohio State researchers working on new way to treat drug-resistant cancer

Researchers at The Ohio State University are working on a new way to treat drug-resistant cancer that the ancient Greeks would approve of--only it's not a Trojan horse, but DNA that hides the invading force. [More]
Cardiac clot-busting drug decreases mortality in hemorrhagic stroke patients

Cardiac clot-busting drug decreases mortality in hemorrhagic stroke patients

Reporting on the results of a phase III international clinical trial, Johns Hopkins Medicine physicians say use of a cardiac clot-busting drug to treat strokes that cause brain bleeding safely decreased the death rate in patients by 10 percent, compared to a control group receiving saline. [More]
UA College of Pharmacy assistant professor developing dry powder inhalers to treat pulmonary diseases

UA College of Pharmacy assistant professor developing dry powder inhalers to treat pulmonary diseases

Heidi M. Mansour, PhD, assistant professor in the University of Arizona College of Pharmacy, is working to develop advanced dry powder inhalers to treat and prevent pulmonary diseases. [More]
Newly developed intravital microscopy system proves safe for use in humans

Newly developed intravital microscopy system proves safe for use in humans

A team of Roswell Park Cancer Institute researchers has developed and evaluated the first intravital microscopy system shown to be safe for use in humans. Writing in the journal Nature Communications, the scientists report that their proprietary technology enabled them, for the first time ever, to visualize tumor blood vessels in real time. [More]
New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Chemotherapy isn't supposed to make your hair fall out -- it's supposed to kill cancer cells. A new molecular delivery system created at U of T Engineering could help ensure that chemotherapy drugs get to their target while minimizing collateral damage. [More]
Virginia Tech scientist finds way to potentially track and stop viruses

Virginia Tech scientist finds way to potentially track and stop viruses

Viruses are molecular thieves that take from their hosts under the cloak of darkness. But now a Virginia Tech scientist has found a way to not only track viral hijackers, but also potentially stop them from replicating. [More]
Terumo CV Group introduces new addition to CAPIOX Oxygenator portfolio

Terumo CV Group introduces new addition to CAPIOX Oxygenator portfolio

Terumo Cardiovascular Group introduces the newest addition to the CAPIOX Oxygenator portfolio – the CAPIOX FX Advance Oxygenator. The CAPIOX FX Advance replaces the current CAPIOX FX15 and FX25 line of oxygenators manufactured in Elkton, Maryland. [More]
Celator provides update on Phase 3 clinical trial of VYXEOS in patients with untreated high-risk AML

Celator provides update on Phase 3 clinical trial of VYXEOS in patients with untreated high-risk AML

Celator Pharmaceuticals, Inc. today announced that the Phase 3 clinical trial of VYXEOS (cytarabine:daunorubicin) Liposome for Injection (also known as CPX-351) in patients with untreated high-risk (secondary) acute myeloid leukemia (AML) has reached its pre-specified number of events required for the analysis of overall survival. [More]
Nine researchers win EPSRC Healthcare Technologies Challenge Awards

Nine researchers win EPSRC Healthcare Technologies Challenge Awards

Nine researchers, working on innovative projects that promise to improve healthcare diagnosis and treatment, across a wide spread of issues, were today announced as the first recipients of the Engineering and Physical Sciences Research Council's (EPSRC) Healthcare Technologies Challenge Awards. [More]
Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes. [More]
Implantable device could help deliver toxic cocktail of drugs directly to pancreatic tumors

Implantable device could help deliver toxic cocktail of drugs directly to pancreatic tumors

A highly lethal cancer sometimes requires large doses of highly toxic drugs. However, a blitzkrieg approach can be unfeasible for some patients due to severe side effects. Now a powerhouse team of researchers at the University of North Carolina at Chapel Hill has revealed that an implantable device can deliver a particularly toxic cocktail of drugs directly to pancreatic tumors to stunt their growth or in some cases, shrink them - all while showing signs that the rest of the body would be spared toxic side effects. [More]
Asian manufacturers wear testing offered by Lucideon & Hong Kong standards and testing center collaboration

Asian manufacturers wear testing offered by Lucideon & Hong Kong standards and testing center collaboration

Lucideon, the international materials technology company, has announced that it has extended its collaboration agreement with the Hong Kong Standards and Testing Centre (STC) to include wear testing of orthopaedic hip and knee implants. [More]
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