Ductal Carcinoma News and Research

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Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Study finds women with DCIS diagnosed outside NHS screening face fourfold increase in breast cancer mortality

Researchers compared the risks of aggressive breast cancers and mortality following DCIS undetected during screening in the general public to those identified through the NHS breast screening program.

29 Jan 2024

Missing NHS screenings linked to significantly higher breast cancer risk

Women who are diagnosed with ductal carcinoma in situ (DCIS) outside the NHS breast screening programme are around four times as likely to develop invasive breast cancer and to die from breast cancer than women in the general population, finds a study published by The BMJ today.

24 Jan 2024

Evaluating the effectiveness and safety of single-port robot-assisted technique in nipple-sparing mastectomy procedures

Researchers evaluated the safety and feasibility of a single-port (SP) robotic-assisted approach for performing nipple-sparing mastectomies (NSM).

19 Jan 2024

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

AI model accurately predicts breast cancer risk across multiple races

A deep learning artificial intelligence (AI) model that was developed using only mammogram image biomarkers accurately predicted both ductal carcinoma in situ (DCIS) and invasive carcinoma, according to research being presented today at the annual meeting of the Radiological Society of North America.

29 Nov 2023

Researchers develop gene classifier to predict DCIS risk of cancer progression

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2023

Unraveling the role of HER2 mutant alleles in breast cancer

A new editorial paper was published in Oncotarget's Volume 14 on October 31, 2023, entitled, "The uncharted role of HER2 mutant alleles in breast cancer."

6 Nov 2023

Air pollution fueling a spike in breast cancer risk

New study finds that exposure to PM2.5 air pollution increases the risk of breast cancer in women by 8% for each 10 µg/m3 increase. The groundbreaking research is the first to provide concrete evidence linking fine particulate matter to ER+ breast cancer.

13 Sep 2023

AI for breast cancer screening can perform just as well as human readers

Using a standardized assessment, researchers in the UK compared the performance of a commercially available artificial intelligence (AI) algorithm with human readers of screening mammograms.

5 Sep 2023

New model predicts 10-year risk of dying from breast cancer

A team of researchers at the University of Oxford, led by the Nuffield Department of Primary Care Health Sciences, have developed a new model that reliably predicts a woman's likelihood of developing and then dying of breast cancer within a decade.

24 Aug 2023

Cancer's silent progression: research delves into evolutionary clues in breast cancer

Researchers performed phylogenetic analyses to trace the evolution of breast cancer and precursor lesions.

2 Aug 2023

Healthy breast fat may protect against invasive breast cancer

Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer.

17 Jul 2023

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Identifying the underlying mechanism associated with the initiation of focal amplification in breast cancer.

19 May 2023

Addressing long-standing issue in women's health: Lumps in the breast

A new research perspective was published in Oncotarget's Volume 14 on April 24, 2023, entitled, "Crossroads: the role of biomarkers in the management of lumps in the breast."

3 May 2023

AI can analyze breast mass images to accurately identify cancer in low-resource settings

Artificial intelligence (AI) can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer, according to a study published in Radiology, a journal of the Radiological Society of North America.

2 May 2023

NCCN releases new guidelines to help patients understand inflammatory breast cancer

Today, the National Comprehensive Cancer Network has published a new addition to its library of patient resources, expanding the information available for breast cancer.

24 Apr 2023

Study finds ultrasound as an effective standalone diagnostic method for focal breast complaints

Ultrasound is an effective standalone diagnostic method in patients with focal breast complaints, according to a study published in Radiology, a journal of the Radiological Society of North America.

4 Apr 2023

Advancements in understanding and treating breast cancer

Researchers describe recent advancements in breast cancer research.

26 Mar 2023

Study finds better breast cancer screening outcomes with tomosynthesis than mammography

In a study of over a million women, digital breast tomosynthesis (DBT) showed improved breast cancer screening outcomes over screening with standard digital mammography alone.

14 Mar 2023