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Emphysema is a debilitating disease that afflicts more than three million Americans. The disease is caused primarily by smoking and leads to a progressive, irreversible breakdown of lung tissue. This breakdown reduces the amount of lung tissue available for gas exchange and also impairs the lung's ability to inflate and deflate normally. As the disease advances, the most damaged areas of the lung over inflate within the chest cavity, trapping air and preventing the healthier lung areas from functioning normally. Eventually breathing becomes more difficult, leaving patients constantly feeling out-of-breath.
Cambridge scientists successfully create 'mini-lungs' to study cystic fibrosis

Cambridge scientists successfully create 'mini-lungs' to study cystic fibrosis

Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease. [More]
UBMD physician discusses the dangers of hypothermia

UBMD physician discusses the dangers of hypothermia

The arctic cold snap affecting the Midwest and the Northeast this weekend should not be taken lightly, says David Holmes, MD, clinical associate professor of family medicine in the University at Buffalo School of Medicine and Biomedical Sciences. [More]
DNA strands predict life expectancy

DNA strands predict life expectancy

BYU biologist Jonathan Alder has a startling secret he doesn't freely share: he knows when most of us are going to die. [More]
UofL study investigates safety, effectiveness of EBV for treating emphysema symptoms

UofL study investigates safety, effectiveness of EBV for treating emphysema symptoms

The University of Louisville has launched a research trial to study an investigational medical device designed to aid patients with emphysema by shutting off the diseased part of the lung. UofL is the only site in Kentucky among 14 nationwide testing the device. [More]
TERT mutations may make smokers more susceptible to emphysema

TERT mutations may make smokers more susceptible to emphysema

Mutations in a gene that helps repair damaged chromosome ends may make smokers — especially female smokers — more susceptible to emphysema, according to results of a new study led by Johns Hopkins Kimmel Cancer Center researchers. [More]
New study finds that poor sleep may lead to dementia

New study finds that poor sleep may lead to dementia

People who have sleep apnea or spend less time in deep sleep may be more likely to have changes in the brain that are associated with dementia, according to a new study published in the December 10, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
BTG agrees to acquire PneumRx for $475 million

BTG agrees to acquire PneumRx for $475 million

PneumRx, Inc., a leader in the field of interventional pulmonology, today announced that it has signed an agreement to be acquired by BTG Plc in a deal worth up to $475 million, based on an initial consideration of $230 million and up to $245 million in performance-related milestone payments. [More]
Persistent eosinophilia common in COPD

Persistent eosinophilia common in COPD

More than one-third of patients with chronic obstructive pulmonary disease have persistent eosinophilia, researchers report in the European Respiratory Journal. [More]
Nutrition treatment for older COPD patients shows better outcomes

Nutrition treatment for older COPD patients shows better outcomes

People aged 65 and older, who were being treated for chronic obstructive pulmonary disease (COPD) in the hospital and received nutrition treatment (oral nutrition supplements) had reduced lengths of stay, hospital costs and chances of returning to the hospital within 30-days, according to a study published in CHEST. [More]
New algorithm could help determine how to treat patients having difficulty breathing

New algorithm could help determine how to treat patients having difficulty breathing

Paramedics respond to a 911 call to find an elderly patient who's having difficulty breathing. Anxious and disoriented, the patient has trouble remembering all the medications he's taking, and with his shortness of breath, speaking is difficult. Is he suffering from acute emphysema or heart failure? The symptoms look the same, but initiating the wrong treatment regimen will increase the patient's risk of severe complications. [More]
Boehringer Ingelheim announces availability of Striverdi Respimat Inhalation Spray 5 mcg in the U.S.

Boehringer Ingelheim announces availability of Striverdi Respimat Inhalation Spray 5 mcg in the U.S.

Boehringer Ingelheim today announced that Striverdi Respimat (olodaterol) Inhalation Spray 5 mcg is now available by prescription in pharmacies across the United States. [More]
Study demonstrates longer-term benefits of Lung Flute for COPD patients

Study demonstrates longer-term benefits of Lung Flute for COPD patients

Patients with chronic obstructive pulmonary disease (COPD) report improved symptoms and health status when they use a hand-held respiratory device called the Lung Flute-, according to a new study by the University at Buffalo. Usually caused by smoking, COPD, which includes chronic bronchitis and emphysema, is the third leading cause of death in the U.S. [More]
Distinct features of COPD–asthma overlap syndrome identified

Distinct features of COPD–asthma overlap syndrome identified

US researchers have shown that patients with both chronic obstructive pulmonary disease and asthma have more exacerbations, less emphysema and more airway disease than patients with COPD alone. [More]
Biochemists discover proteins that could lead to better treatments for life-threatening infections

Biochemists discover proteins that could lead to better treatments for life-threatening infections

Two Kansas State University biochemists have discovered a family of proteins that could lead to better treatments for Staphylococcus aureus, a pathogenic bacterium that can cause more than 60,000 potentially life-threatening infections each year. [More]
Greater Toronto Area continues to violate Canada-wide standards for ozone air pollution

Greater Toronto Area continues to violate Canada-wide standards for ozone air pollution

A new study shows that while the Greater Toronto Area has significantly reduced some of the toxins that contribute to smog, the city continues to violate the Canada-wide standards for ozone air pollution. [More]
Boehringer Ingelheim announces FDA acceptance of NDA filing for tiotropium and olodaterol FDC

Boehringer Ingelheim announces FDA acceptance of NDA filing for tiotropium and olodaterol FDC

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration accepted for review the New Drug Application (NDA) for the fixed-dose combination (FDC) of tiotropium and olodaterol delivered via the Respimat inhaler for the proposed indication of long-term, once-daily maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. [More]
Study finds link between common respiratory diseases and increased risk of lung cancer

Study finds link between common respiratory diseases and increased risk of lung cancer

Links between a number of common respiratory diseases and an increased risk of developing lung cancer have been found in a large pooled analysis of seven studies involving more than 25,000 individuals. [More]
Chronic obstructive pulmonary disease flare-ups: an interview with Dr. MeiLan Han, University of Michigan and Scott Cerreta, Director of Education, COPD Foundation

Chronic obstructive pulmonary disease flare-ups: an interview with Dr. MeiLan Han, University of Michigan and Scott Cerreta, Director of Education, COPD Foundation

During a flare-up, symptoms of a patient’s COPD worsen significantly, and breathing becomes more difficult. A persistent increase in shortness of breath, cough and sputum production are typical symptoms. [More]
Xenex testifies before U.S. House of Representatives on effectiveness of UV disinfection system in reducing HAI rates

Xenex testifies before U.S. House of Representatives on effectiveness of UV disinfection system in reducing HAI rates

Xenex Disinfection Services, the world leader in UV room disinfection systems, testified yesterday before the U.S. House of Representatives Committee on Science, Space, and Technology; Subcommittee on Research and Technology; and Subcommittee on Oversight. [More]
Exchange plans attract sicker consumers

Exchange plans attract sicker consumers

An analysis of early medical claims shows that Americans enrolled in the health law's exchange plans have higher rates of serious health problems, according to The Wall Street Journal. Meanwhile, The Washington Post reports that some small employers buying coverage for their workers are struggling with costs and logistics. [More]
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