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UTHealth researchers receive $11 million grant to study prion diseases

UTHealth researchers receive $11 million grant to study prion diseases

Led by Claudio Soto, Ph.D., researchers from McGovern Medical School at The University of Texas Health Science Center at Houston have been awarded $11 million from the National Institute of Allergy and Infectious Diseases to study the pathogenesis, transmission and detection of prion diseases - such as chronic wasting disease in deer - that can potentially spread to humans. [More]
Study provides new insight into poorly understood effects of high explosive blasts in male soldiers

Study provides new insight into poorly understood effects of high explosive blasts in male soldiers

Scientists have identified a distinctive pattern of injury in the brains of eight deceased military personnel who survived high explosive attacks and died between 4 days and 9 years later from their injuries or other causes. [More]
Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say. [More]
Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food safety because TSEs have the potential of crossing from animals to humans, as seen with the spread of mad cow disease, or bovine spongiform encephalopathy (BSE). A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk. [More]
Analysis reveals improved survivorship for acute liver failure patients

Analysis reveals improved survivorship for acute liver failure patients

More patients hospitalized with acute liver failure - often the result of acetaminophen overdose - are surviving, including those who receive a liver transplant and those who don't, an analysis led by a UT Southwestern Medical Center researcher showed. [More]
Stimulus-induced discharges in critically ill not linked to in-hospital death

Stimulus-induced discharges in critically ill not linked to in-hospital death

Stimulus-induced rhythmic, periodic or ictal discharges in critically ill patients are not independently associated with in-hospital death, but are often associated with other electrographic abnormalities signalling poor outcomes, electroencephalography findings show. [More]
Preliminary results of blood test to diagnose CTE during life published in Journal of Alzheimer's Disease

Preliminary results of blood test to diagnose CTE during life published in Journal of Alzheimer's Disease

Exosome Sciences, Inc., in collaboration with majority shareholder Aethlon Medical, Inc. and investigators at Boston University and the University of Washington, announced today the published preliminary results of possibly the first blood test to detect the neurodegenerative disease, Chronic Traumatic Encephalopathy (CTE) during life. [More]
Study provides new insights into Retigabine drug

Study provides new insights into Retigabine drug

A study published ahead of print in the The Journal of General Physiology has revealed new insights into Retigabine, a known pharmacological treatment for epilepsy. [More]
Study: Delirium, muscle weakness and other neurological complications of sepsis poorly understood

Study: Delirium, muscle weakness and other neurological complications of sepsis poorly understood

Delirium, muscle weakness and other neurological complications of sepsis often are overlooked and poorly understood, according to a study published in the journal Current Neurology and Neurosciences Reports. [More]
Results from STRIVE trial of enzalutamide versus bicalutamide in CRPC published in Journal of Clinical Oncology

Results from STRIVE trial of enzalutamide versus bicalutamide in CRPC published in Journal of Clinical Oncology

Astellas US LLC, a United States (U.S.) subsidiary of Tokyo-based Astellas Pharma Inc., and Medivation, Inc. today announced that results from the STRIVE trial of enzalutamide compared to bicalutamide in men with castration-resistant prostate cancer (CRPC) were published in the Journal of Clinical Oncology. [More]
Oxeia accelerating development of neurometabolic treatments for concussions

Oxeia accelerating development of neurometabolic treatments for concussions

Oxeia Biopharmaceuticals, Inc., a biotechnology company, is catalyzing the development of first-in-class neurometabolic treatments for concussions and other aspects of brain injury. [More]
Study findings may help explain why risk of stroke changes after menopause

Study findings may help explain why risk of stroke changes after menopause

Risk of stroke in women may come down to a compound the body produces from estrogen known as 2-methoxyestradiol (2-ME). Furthermore, the compound's therapeutic potential may extend beyond treating stroke in women to healing brain injuries in men, a new study in American Journal of Physiology—Endocrinology and Metabolism reports. [More]
Concussions related to sports and recreation activities affect millions of Americans

Concussions related to sports and recreation activities affect millions of Americans

Every year, between 3 million and 4 million Americans suffer concussions in sports and recreation. Head impacts and concussions caused by contact sports are a quickly growing epidemic among young athletes. [More]
New UTMB study reveals link between traumatic brain injury and Alzheimer's disease

New UTMB study reveals link between traumatic brain injury and Alzheimer's disease

A new study from The University of Texas Medical Branch at Galveston fills an important gap in understanding the link between traumatic brain injury and neurodegenerative disorders such as Alzheimer's disease. [More]
Researchers awarded $16 million NIH/NINDS grant to create methods for detecting CTE during life

Researchers awarded $16 million NIH/NINDS grant to create methods for detecting CTE during life

Researchers from Boston University, the Cleveland Clinic, Banner Alzheimer's Institute and Brigham and Women's Hospital in Boston, have been awarded a $16 million grant from the National Institutes of Health/National Institute of Neurological Disorders and Stroke. [More]
Amgen’s Phase 2 data supports safety, efficacy of BLINCYTO in ALL patients with minimal residual disease

Amgen’s Phase 2 data supports safety, efficacy of BLINCYTO in ALL patients with minimal residual disease

Amgen today announced that new data from three Phase 2 trials support the efficacy and safety of BLINCYTO (blinatumomab) in adults with acute lymphoblastic leukemia (ALL). [More]

European liver patients’ association launches call to action report for the treatment of heapatic encephalopathy

ELPA today launched a new call to action report ‘Time to DeLiver: Getting a Grip on HE’ at the European Parliament in Brussels. This is the first report from Europe to highlight the significant burden of hepatic encephalopathy on patients, their carers, families and society. [More]
Study confirms neuroprotective effects of hypothermia in newborns with HIE

Study confirms neuroprotective effects of hypothermia in newborns with HIE

A unique study at Children's Hospital Los Angeles of newborns treated with hypothermia for hypoxic-ischemic encephalopathy (HIE) - a condition that occurs when the brain is deprived of an adequate oxygen supply - confirms its neuroprotective effects on the brain. [More]
Allergan's anti-infective portfolio to be highlighted at IDWeek 2015

Allergan's anti-infective portfolio to be highlighted at IDWeek 2015

Allergan plc today announced that its infectious disease portfolio will be featured in 13 abstracts highlighting data at IDWeek 2015, which takes place from October 7-11, 2015, in San Diego. [More]
New concussion program aims at treating football players with predisposition to CTE

New concussion program aims at treating football players with predisposition to CTE

Upledger Institute Clinic in conjunction with the Ricky Williams Foundation and the Dr. John E. Upledger Foundation announced earlier today, the start of their second concussion therapy research program aimed at treating current and former members of the NFL and the Canadian Football League. [More]
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