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Many women fail to understand risks of unapproved, untested bioidentical hormone therapies

Many women fail to understand risks of unapproved, untested bioidentical hormone therapies

From 28% to 68% of women using hormones at menopause take compounded, so-called "bioidentical" hormones, but women don't understand the risks of these unapproved, untested treatments, shows an analysis of two large surveys, which was published online today in Menopause, the journal of The North American Menopause Society. [More]
Study: Risk of uterine sarcoma fairly low in women following hysterectomy

Study: Risk of uterine sarcoma fairly low in women following hysterectomy

Uterine sarcoma - a potentially aggressive type of cancer that forms in tissues in the uterus - was found in 0.22 % of women following a hysterectomy for benign conditions, a new large-scale study by the University of Michigan departments of Obstetrics and Gynecology, and Surgery finds. [More]
Risk of ovarian cancer increased with even short-term HRT use

Risk of ovarian cancer increased with even short-term HRT use

There has been much uncertainty regarding the risk of cancer associated with taking hormone replacement therapy (HRT) for the menopause. An analysis of all available evidence published in The Lancet today shows that HRT, even when taken for only a few years, significantly increases the risk of developing the two most common types of ovarian cancer. [More]
Final Phase 1 data of zoptarelin doxorubicin Phase 1/2 trial published in Clinical Cancer Research

Final Phase 1 data of zoptarelin doxorubicin Phase 1/2 trial published in Clinical Cancer Research

Aeterna Zentaris Inc. today announced that an article on final data for the Phase 1 portion of the ongoing Phase 1/2 trial in prostate cancer with zoptarelin doxorubicin (formerly AEZS-108), a hybrid molecule composed of a synthetic peptide carrier and a well-known chemotherapy agent, doxorubicin, has been published in the December issue of Clinical Cancer Research. [More]
Preventive effect of tamoxifen drug for breast cancer remains virtually constant for 20 years

Preventive effect of tamoxifen drug for breast cancer remains virtually constant for 20 years

The preventive effect of breast cancer drug 'tamoxifen' remains virtually constant for at least 20 years - with rates reduced by around 30 per cent - new analysis published in The Lancet Oncology reveals. [More]
Study shows how exosomes secreted by tumor cells promote tumor growth

Study shows how exosomes secreted by tumor cells promote tumor growth

Researchers at the Bellvitge Biomedical Research Institute of Bellvitge, the Catalan Institute of Oncology and the University Hospital of Bellvitge have participated in an international study published in the journal Cancer Cell that describes how exosomes secreted by tumor cells contain protein and microRNA molecules capable of transform neighboring cells into tumoral cells promoting tumor growth. [More]
RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Scientists say they have identified in about 20 percent of colorectal and endometrial cancers a genetic mutation that had been overlooked in recent large, comprehensive gene searches. With this discovery, the altered gene, called RNF43, now ranks as one of the most common mutations in the two cancer types. [More]
New research may help identify individuals at increased risk of pancreatic cancer

New research may help identify individuals at increased risk of pancreatic cancer

New research that provides a better understanding of pancreatic cancer may help identify individuals at increased risk. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society. [More]
ERK and JNK enzymes may offer solutions for treating endometrial, colon cancers

ERK and JNK enzymes may offer solutions for treating endometrial, colon cancers

In the quest to solve cancer's mysteries, they come in handy when describing tongue-twisting processes and pathways that somehow allow tumors to form and thrive. Two examples are ERK (extracellular-signal-related kinase) and JNK (c-June N-Terminal Kinase), enzymes that may offer unexpected solutions for treating some endometrial and colon cancers. [More]
RT with concurrent chemotherapy post surgery is effective for treating endometrial cancer

RT with concurrent chemotherapy post surgery is effective for treating endometrial cancer

Radiation therapy with concurrent paclitaxel chemotherapy following surgery is an effective treatment for patients with high-risk endometrial cancer, according to a study published in the September 1, 2014 edition of the International Journal of Radiation Oncology ● Biology ● Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO). [More]
Scientists identify genetic mutations in endometrioid endometrial carcinoma

Scientists identify genetic mutations in endometrioid endometrial carcinoma

Parents of twins often tell them apart through subtle differences such as facial expression, moles, voice tone and gait. Similarly, physicians treating women with endometrial cancer must be able to distinguish between different versions of this disease form that, on the surface, appear the same. [More]
Peer groups, clinicians play critical role in development of effective breastfeeding programs

Peer groups, clinicians play critical role in development of effective breastfeeding programs

The support of peer groups and clinicians is critical to the development of effective breastfeeding programs, according to recent University of Georgia research. [More]
Dasatinib: Leukemia drug shows promise for treating skin, breast and other cancers

Dasatinib: Leukemia drug shows promise for treating skin, breast and other cancers

A leukemia drug called dasatinib shows promise for treating skin, breast and several other cancers, according to researchers at Loyola University Chicago Stritch School of Medicine. [More]
New guideline recommends genetic testing of tumors for colorectal cancer patients

New guideline recommends genetic testing of tumors for colorectal cancer patients

Of the 143,000 patients diagnosed with colorectal cancer annually in the U.S., up to 25 percent have a familial risk of colorectal cancer. A new guideline from the U.S. Multi-Society Task Force on Colorectal Cancer recommends genetic testing of tumors for all newly diagnosed colorectal cancer patients. [More]
Aeterna Zentaris signs strategic co-promotion services agreement with ASCEND

Aeterna Zentaris signs strategic co-promotion services agreement with ASCEND

Aeterna Zentaris Inc. today announced a strategic co-promotion services agreement with ASCEND Therapeutics US, LLC. [More]
Study confirms effectiveness of EKF PointMan technology for isolating low-level DNA mutations in blood

Study confirms effectiveness of EKF PointMan technology for isolating low-level DNA mutations in blood

EKF Diagnostics, the global diagnostics company, announces that the latest results from its collaboration with the Institute of Life Sciences at the University of Swansea, UK, have continued to confirm the effectiveness of its PointMan DNA enrichment technology for isolating and characterizing low-level DNA mutations in blood. [More]
New drug delivered through skin effective in treatment of breast cancer

New drug delivered through skin effective in treatment of breast cancer

A drug that has proven effective in the prevention and treatment of breast cancer, but with serious side-effects, may be delivered effectively through the skin using a new topical drug-delivery system. [More]
Pseudogenes may play key role in the discovery of new biomarkers

Pseudogenes may play key role in the discovery of new biomarkers

Dysfunctional, unloved and seemingly of little use, these poor-cousin relatives of genes have lost their protein-coding abilities. They contain material not essential for an organism's survival and are the "last stop" for removal of genomic waste. [More]
High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

It has been known for its flavorful addition to soups and as a delicacy for dogs but bone marrow fat may also have untapped health benefits, new research finds. [More]
Video interview highlights latest research developments in women’s reproductive health using Chromatrap solid state ChIP assay

Video interview highlights latest research developments in women’s reproductive health using Chromatrap solid state ChIP assay

An informative video interview with Professor Steve Conlan of the College of Medicine at Swansea University (UK) highlights the latest research developments in women’s reproductive health using unique molecular biology tools. [More]