Enterocolitis News and Research

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Study: Black infants disproportionately die from necrotizing enterocolitis compared to White babies

A study published in JAMA Network Open has found that in the US between 1999 and 2020, Black infants disproportionately died from necrotizing enterocolitis compared to White infants, despite overall improvements in the rates of death from the disease.

3 Mar 2023

The role of omega-3 and omega-6 metabolites during pregnancy

Omega-3 and -6 fatty acids ingested through the diet are metabolized into bioactive compounds that influence inflammation. In a recent the journal Biomedicines study, scientists reviewed the existing literature and summarized their findings related to the role of omega-3 and omega-6 metabolites during pregnancy.

15 Jan 2023

LSU Health New Orleans to receive patent for a noninvasive test to diagnose fatal condition in preemies

US Patent 11,493,515 will be issued to LSU Health New Orleans on November 8, 2022, for a noninvasive test that more accurately diagnoses a potentially fatal condition in premature infants.

7 Nov 2022

Antenatal steroid therapy for pregnant women may improve survival among extremely preterm infants

Steroid treatment before birth appears to improve survival and reduce complications among extremely preterm infants, according to a study funded by the National Institutes of Health.

26 Sep 2022

Umbilical cord milking may be safe, more effective for non-vigorous term and near- term infants

A treatment to move blood from the umbilical cord into an infant's body may improve the overall health of newborns classified as non-vigorous—limp, pale and with minimal breathing, suggests a study funded by the National Institutes of Health.

7 Sep 2022

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Human breastmilk has long been considered "liquid gold" among clinicians treating premature infants in a newborn intensive care unit.

2 Aug 2022

Review may lead to improvements in therapeutic options for preterm infants

One in two premature babies receives transfusions of red blood cells (RBC) due to anemia. There are no generally accepted clinical guidelines for the degree of anemia necessitating blood transfusions.

26 Jul 2022

Fortified breastmilk does not influence IQ in preterm infants

Scientists compare the cognitive and psychological development of preterm infants who were breastfed with or without fortification.

13 Jul 2022

How is the microbiome of an infant influenced by mother's bacteria?

A recent study explores the sources and functional importance of certain key species in the mother-infant transmission of the microbiota.

5 Jul 2022

The effects of maternal SARS-CoV-2 infection on the newborn child

Even as the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread worldwide, interest in understanding the sequelae of the disease is growing. A new preprint research paper examines the outcomes of babies born to mothers infected with the virus during pregnancy.

24 May 2022

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

9 May 2022

Gut virome may warn of a serious and often fatal disease in preterm infants

Immediately after birth, human infants begin to develop a complex, interwoven fabric of microbes in their gut.

26 Apr 2022

Cheap and accessible methods for genome sequencing will help tackle future pandemics

A worldwide consortium of scientists, led by the Earlham Institute and the University of Liverpool in the UK, mark a significant milestone in equipping researchers in low- and middle-income countries (LMICs) with cheap and accessible methods for sequencing large collections of bacterial pathogens - at a cost of less than $10USD per genome.

21 Dec 2021

Neonatal outcomes of preterm infants born during COVID lockdowns in Melbourne, Australia

A team of researchers from Australian institutes examined the consequences of community-wide lockdowns on neonatal outcomes of preterm infants, with a secondary focus on the underlying rates of systemic inflammation in infants and mothers around the time of birth.

5 Oct 2021

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant's intestinal lining and causes death in up to a third of the cases.

23 Sep 2021

'Good cholesterol' protects the liver from inflammation and injury, study shows

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury.

22 Jul 2021

Protein found in mice’s immune system could protect babies from necrotizing enterocolitis

The intestinal disease necrotizing enterocolitis is a leading cause of death among premature infants born in the U.S. and across the globe.

18 Jun 2021

Placental-derived stem cell therapy shows promise to heal intestinal disease in premature babies

An intestinal bowel disease that affects up to 10 percent of premature infants at a very vulnerable and developmentally crucial time can lead to serious infection and death.

27 Apr 2021

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut.

20 Apr 2021

Probiotic supplements increase the diversity of intestinal bacteria in extremely preterm infants

Extremely preterm infants can suffer from a life-threatening inflammation of the gut. A new clinical study has shown that supplements of a lactic acid bacterium may have positive effects by increasing the diversity of intestinal bacteria in these infants.

11 Mar 2021