Epstein Barr Virus News and Research

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Epstein-Barr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time.

Symptoms of infectious mononucleosis are fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. Heart problems or involvement of the central nervous system occurs only rarely, and infectious mononucleosis is almost never fatal. There are no known associations between active EBV infection and problems during pregnancy, such as miscarriages or birth defects. Although the symptoms of infectious mononucleosis usually resolve in 1 or 2 months, EBV remains dormant or latent in a few cells in the throat and blood for the rest of the person's life. Periodically, the virus can reactivate and is commonly found in the saliva of infected persons. This reactivation usually occurs without symptoms of illness.
Molecular classification of gastric cancer subtypes could shape tailored treatment options

Molecular classification of gastric cancer subtypes could shape tailored treatment options

Herpes virus in mountain gorillas has similarity to EBV found in humans

Herpes virus in mountain gorillas has similarity to EBV found in humans

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Preliminary study reveals promising results of new treatment for progressive MS

Preliminary study reveals promising results of new treatment for progressive MS

Johns Hopkins researchers find no evidence of CMV in aggressive brain cancer tissues

Johns Hopkins researchers find no evidence of CMV in aggressive brain cancer tissues

Research shows how protein component of Epstein-Barr virus promotes development of cancer

Research shows how protein component of Epstein-Barr virus promotes development of cancer

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Scientists isolate and characterize therapy-resistant dormant leukemia cells

Scientists isolate and characterize therapy-resistant dormant leukemia cells

ACS approves $1.7 million funding for new research grants to Yale University

ACS approves $1.7 million funding for new research grants to Yale University

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Majority of cancers can be caused by infectious agents in sub-Saharan Africa, reveals study

Majority of cancers can be caused by infectious agents in sub-Saharan Africa, reveals study

Research could provide new insights into finding cure for chronic infections

Research could provide new insights into finding cure for chronic infections

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

Experts use next-generation genetic sequencing to diagnose suspected brain infections

Experts use next-generation genetic sequencing to diagnose suspected brain infections

Heart failure drug has unexpected ability to block herpesvirus infection

Heart failure drug has unexpected ability to block herpesvirus infection

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Novel strategies on the way for difficult-to-treat head and neck cancer

Novel strategies on the way for difficult-to-treat head and neck cancer

Envarsus XR granted FDA orphan drug designation for prophylaxis of organ rejection in kidney transplant patients

Envarsus XR granted FDA orphan drug designation for prophylaxis of organ rejection in kidney transplant patients

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies