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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.
Female sex hormone estradiol may protect women against sexually transmitted viral infections

Female sex hormone estradiol may protect women against sexually transmitted viral infections

A team of researchers led by McMaster University's Charu Kaushic has revealed for the first time how estradiol, a female sex hormone present during the menstrual cycle and found in oral contraceptives, may work to protect women against sexually transmitted viral infections. [More]
Derivatives of female sex hormones can influence natural melanin production, study suggests

Derivatives of female sex hormones can influence natural melanin production, study suggests

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians. [More]
Hormonal contraception may increase susceptibility of women to genital infection

Hormonal contraception may increase susceptibility of women to genital infection

Women account for approximately half of all individuals living with HIV worldwide, and researchers wanted to identify the risk factors that increase susceptibility of women to genital infection. [More]
Certain types of hormonal contraceptives may increase risk of seizures in women with epilepsy

Certain types of hormonal contraceptives may increase risk of seizures in women with epilepsy

Could certain types of hormonal contraceptives cause an increase in seizures in women with epilepsy? A recent Texas A&M Health Science Center study suggests that ethinyl estradiol, the primary component of oral contraceptives, could be detrimental to the epileptic brain. [More]
Study findings may help explain why risk of stroke changes after menopause

Study findings may help explain why risk of stroke changes after menopause

Risk of stroke in women may come down to a compound the body produces from estrogen known as 2-methoxyestradiol (2-ME). Furthermore, the compound's therapeutic potential may extend beyond treating stroke in women to healing brain injuries in men, a new study in American Journal of Physiology—Endocrinology and Metabolism reports. [More]
Mylan announces U.S. launch of generic Ortho Tri-Cyclen Lo Tablets

Mylan announces U.S. launch of generic Ortho Tri-Cyclen Lo Tablets

Mylan N.V. today announced the U.S. launch of Norgestimate and Ethinyl Estradiol Tablets USP, 0.18 mg/0.025 mg, 0.215 mg/0.025 mg, and 0.25 mg/0.025 mg, which is the generic version of Janssen's Ortho Tri-Cyclen Lo Tablets. [More]
IU researchers discover hormonal mechanism that links short winter days with increased aggression in females

IU researchers discover hormonal mechanism that links short winter days with increased aggression in females

Indiana University researchers have discovered a hormonal mechanism in hamsters that connects short winter days with increased aggression in females, and that it differs from the mechanism that controls this same response in males. [More]
Estradiol fluctuation may enhance emotional sensitivity to psychosocial stress during menopausal transition

Estradiol fluctuation may enhance emotional sensitivity to psychosocial stress during menopausal transition

If you're feeling a little blue during the transition to menopause, there's good reason, according to a new study being reported online today in Menopause, the journal of The North American Menopause Society (NAMS). The study from the Department of Psychiatry at the University of North Carolina at Chapel Hill suggests that the estradiol (a form of estrogen) fluctuation that is common during the menopausal transition may enhance emotional sensitivity to psychosocial stress. [More]
Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Estrogen-mimicking chemicals called parabens, which are commonly found in an array of personal care products, may be more dangerous at lower doses than previously thought, according to a new study. [More]
Breakthrough research suggests that female sex hormone may save lives on the battlefield

Breakthrough research suggests that female sex hormone may save lives on the battlefield

Breakthrough research suggests a female sex hormone may be the key to saving lives on the battlefield, where between 2001 and 2011 more than 80 percent of potentially preventable U.S. war injury deaths resulted from blood loss. [More]
HDL not so good in protecting women against atherosclerosis, study shows

HDL not so good in protecting women against atherosclerosis, study shows

What has previously been known as good cholesterol--high density lipoprotein (HDL)--has now been shown to be not so good in protecting women against atherosclerosis while they are transitioning through menopause. That's according to a new study from the University of Pittsburgh Graduate School of Public Health that was presented last week at the annual meeting of The North American Menopause Society in Las Vegas. [More]
Female mice exposed to endocrine disruptors may show decreased metabolism, physical activity in offspring

Female mice exposed to endocrine disruptors may show decreased metabolism, physical activity in offspring

Endocrine disruptors are contaminants that interfere with endocrine or hormone systems and can cause tumors, birth defects and developmental disorders in mammals. Often, these contaminants are used in a variety of consumer products, such as water bottles, dental composites and resins used to line metal food and beverage containers. [More]
Comprehensive review looks at safety, efficacy of treatment options for premenstrual dysphoric disorder

Comprehensive review looks at safety, efficacy of treatment options for premenstrual dysphoric disorder

Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome that causes major disruption in several areas of life for many women. Many treatment options have been proposed, but which are most effective? A comprehensive review of the evidence, including specific treatment guidelines, is presented in the September Journal of Psychiatric Practice, published by Wolters Kluwer. [More]
Mylan releases generic version of Yasmin Tablets in the U.S.

Mylan releases generic version of Yasmin Tablets in the U.S.

Mylan N.V. today announced the U.S. launch of Drospirenone and Ethinyl Estradiol Tablets USP, 3 mg/0.03 mg, which is the generic version of Bayer's Yasmin Tablets. Mylan's partner Famy Care Ltd. received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application (ANDA) for this product, which is indicated for use by women to prevent pregnancy. [More]
New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) has been passed down in many families for generations -- causing reproductive and metabolic health problems for millions of women around the world. Yet, its cause remains unknown despite more than 80 years of research since the disorder was first described in 1935. [More]
Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Late- and post-menopausal women have significantly greater volumes of fat around their hearts - a risk factor for heart disease - than their pre-menopausal counterparts, a University of Pittsburgh Graduate School of Public Health study has shown for the first time. [More]
Neuromodulator norepinephrine has direct action on auditory processing of complex signals

Neuromodulator norepinephrine has direct action on auditory processing of complex signals

For neuroscientists studying the intricate mechanisms of hearing in the brain's auditory cortex, a major question has been how a listener can focus in a noisy environment, and how neurochemicals help neurons convey as much embedded information as possible for the rest of the brain to act on. [More]
Water retention linked to changes in sex hormone levels

Water retention linked to changes in sex hormone levels

Water retention—a cause of bloating—is associated with changes in sex hormone levels. Many women experience water retention during menopause, but how sex hormones affect water balance is not understood. A new study in in the American Journal of Physiology—Renal Physiology sheds light on the connection, finding that sex hormones can directly control how the body reabsorbs water. [More]
Previous motherhood alters cognition, neuroplasticity in response to hormone therapy

Previous motherhood alters cognition, neuroplasticity in response to hormone therapy

Hormone therapy (HT) is prescribed to alleviate some of the symptoms of menopause in women. Menopausal women are more likely to be diagnosed with Alzheimer's disease but not other forms of dementia, and HT has been prescribed to treat cognitive decline in post-menopausal women with variable degrees of effectiveness. [More]
Merus Labs International acquires rights to manufacture, market specialty pharmaceutical products in multiple countries

Merus Labs International acquires rights to manufacture, market specialty pharmaceutical products in multiple countries

Merus Labs International Inc. is pleased to announce that one of its wholly owned subsidiaries has signed a definitive agreement to acquire the rights to manufacture, market, and sell two established specialty pharmaceutical products in certain European and other markets. [More]
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