Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

How does the human gut microbiome impact menopause?

A recent study summarizes available information on the relationship between menopause and the gut microbiome.

24 Aug 2022

How do female sex hormones affect sleep, and memory?

Scientists describe the relationship between biological sex, memory, sleep, and hormones in relation to the risk of Alzheimer's disease and related dimentias.

7 Aug 2022

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

Does COVID-19 cause hair loss?

A new study discusses hair loss as a result of COVID-19.

12 Jul 2022

The role of myostatin in female fertility

A new study discusses some of the key functions of myostatin in female reproductive health and disease.

6 Jul 2022

Prolonged use of puberty-delaying medicines among transgender youth linked to lower bone mineral density

A longer duration of treatment with puberty-delaying medications among transgender youth is associated with lower bone mineral density, according to a new study that will be presented Sunday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females.

31 May 2022

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers profiled the binding sites of the entire SARS-CoV-2 spike protein sequence.

26 May 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Life events that influence estrogen levels may be linked to woman's dementia risk in later life

Life events that influence levels of the female hormone estrogen may be linked to a woman's risk of developing dementia in later life, according to new research.

5 Apr 2022

Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

Study measures arterial stiffness in women from wide age range

A study conducted at the University of Jyväskylä in the Faculty of Sport and Health Sciences measured arterial stiffness in women from wide age range.

10 Dec 2021

Acute SARS-CoV-2 infection during pregnancy associated with placental ACE2 shedding

A new study, published on the bioRxiv* preprint server, hypothesized that ACE-2 expression and ADAM17 activity in the placenta is affected by the timing of SARS-CoV-2 infection of the mother.

24 Nov 2021

Research finds variability in PTSD symptoms over the course of menstrual cycle

In women who have experienced trauma, post-traumatic stress disorder symptoms may vary over the course of the menstrual cycle, with more symptoms during the first few days of the cycle when the hormone estradiol is low, and fewer symptoms close to ovulation, when estradiol is high, finds research published by the American Psychological Association.

28 Oct 2021

Women may be more vulnerable to drug addiction and addiction-like behaviors than men

The results of several new studies focusing on sex differences in pain and addiction indicate females could be more susceptible to drug addiction and addiction-like behaviors than males. Researchers also explored the role of lack of sleep on the likeliness to relapse. This is due in part to hormone differences in females and males. Data from the studies will be presented virtually October 19–22 at the American Physiological Society's seventh conference on New Trends in Sex and Gender Medicine.

20 Oct 2021

The pandemic forced my transgender wife to fight our insurer over hormones

For the past eight years, my wife, Ky Hamilton, has undergone gender-affirming hormone therapy. As a transgender woman, she injects Depo-Estradiol liquid estrogen into her thigh once a week.

5 Oct 2021

New simple plasmonic optical fiber biosensing platform for detecting estrogenic endocrine disruptors

Developing the advanced and powerful detection techniques to characterize as many endocrine disruptors as possible with ultra-sensitivity in the environment is still challenging, however highly demanded.

25 Sep 2021

McLean wins NIH grant to explore links between COVID-19 vaccine and menstrual cycle changes

In research that will add important data to the experience of vaccines on women's health, Laura Payne, PhD, director of McLean Hospital's Clinical and Translational Pain Research Laboratory, has received a grant from the National Institutes of Health to explore potential links between SARS-CoV-2 vaccination and menstrual cycle changes.

23 Sep 2021

KU researcher wins $1.25 million award to investigate the vital role of sex hormones in tissue repair

Our ability to heal and regenerate new tissue after an injury has much to do with biological sex. For instance, following menopause, the loss of sex-hormone signaling in women can lead to degenerative diseases such as osteoporosis and osteoarthritis, where bone and cartilage degrade and become more delicate and brittle because of tissue loss.

21 Sep 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021