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Estrogens are a family of related molecules that stimulate the development and maintenance of female characteristics and sexual reproduction.

The natural estrogens produced by women are steroid molecules, which means that they are derived from a particular type of molecular skeleton containing four rings of carbon atoms, giving the shape shown here. The most prevalent forms of human estrogen are estradiol and estrone. Both are produced and secreted by the ovaries, although estrone is also made in the adrenal glands and other organs.
Painful sex in women after cancer needs to be addressed, UC Davis researcher suggests

Painful sex in women after cancer needs to be addressed, UC Davis researcher suggests

Painful sex in women after cancer treatment is relatively common, often treatable and needs to be addressed by medical providers, a UC Davis oncologist and researcher suggests. [More]
Small RNA molecules could contribute to serious pregnancy complication, study finds

Small RNA molecules could contribute to serious pregnancy complication, study finds

A family of small RNA molecules affects the development of cells that give rise to the placenta - an organ that transfers oxygen and nutrients from mother to fetus -- in ways that could contribute to a serious pregnancy complication, UT Southwestern Medical Center researchers report. [More]
Screening for prolactin receptor could help improve TNBC prognosis and treatment

Screening for prolactin receptor could help improve TNBC prognosis and treatment

A study conducted at the Research Institute of the McGill University Health Centre suggests screening breast cancer patients for the prolactin receptor could improve the prognosis for patient and may help them avoid unnecessary and invasive treatments [More]
New study examines how tumor genome testing helps improve breast cancer treatment

New study examines how tumor genome testing helps improve breast cancer treatment

A new study examines how one early example of precision medicine--tumor genome testing--is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy. [More]
Robot-assisted surgery at NYU Lutheran offers hope to women with endometrial cancer

Robot-assisted surgery at NYU Lutheran offers hope to women with endometrial cancer

Nandi Kumar Carpen, a 51-year-old wife, mother of two young girls, and a nurse at a major city hospital, noticed some "spotty" bleeding outside of her regular menstrual cycle. [More]
Gene variants linked to hot flashes in menopausal women

Gene variants linked to hot flashes in menopausal women

Most women experience hot flashes and night sweats either before or during menopause, but a significant minority don't have these symptoms. Could our genes be a factor in determining which women get hot flashes? [More]
New clinical study to examine novel dietary approach for TNBC

New clinical study to examine novel dietary approach for TNBC

A new clinical trial for women with clinically aggressive triple-negative breast cancer (TNBC) will test a novel theory: Will a diet low in an essential nutrient make TNBC cells more vulnerable to cell killing by a new cancer drug? [More]
Study identifies factors that increase risk for breast cancer in young African American women

Study identifies factors that increase risk for breast cancer in young African American women

Black women under the age of 45 are at increased risk for an aggressive form of breast cancer [estrogen receptor (ER) negative] if they experienced a high number of pregnancies, never breast fed, and/or had higher waist-to-hip ratio. [More]
Activation of chemical with ER-β may help reduce obesity by converting white fat to brown fat

Activation of chemical with ER-β may help reduce obesity by converting white fat to brown fat

New research, published online in The FASEB Journal, suggests that activation of a chemical called Beta-LGND2 by the estrogen receptor Beta (ER-Beta) reduces obesity and metabolic diseases in mice by converting bad fat (white fat) to good fat (brown fat). [More]
Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice. [More]
Endocrine Society issues new guidelines on hypopituitarism

Endocrine Society issues new guidelines on hypopituitarism

The Endocrine Society today issued a Clinical Practice Guideline that recommends treating insufficient hormone levels in individuals with hypopituitarism by replacing hormones at levels as close to the body's natural patterns as possible. [More]
Houston Methodist researcher receives $4 million to create triple negative breast cancer immunotherapy

Houston Methodist researcher receives $4 million to create triple negative breast cancer immunotherapy

Scientists at Houston Methodist received support from the U.S. Department of Defense to reprogram cancer patients' immune cells to attack triple negative breast cancer, the most lethal form of breast cancer. [More]
Predominance of testosterone in males may explain sex difference in ACL injury rates

Predominance of testosterone in males may explain sex difference in ACL injury rates

In studies on rats, Johns Hopkins Medicine scientists report new evidence that the predominance of the hormone testosterone in males may explain why women are up to 10 times more likely than men to injure the anterior cruciate ligament (ACL) in their knees. [More]
New review questions safety of estrogen replacement therapy

New review questions safety of estrogen replacement therapy

Although individuals often consume natural products because of their potential health benefits, a new review indicates that it is not clear whether the benefits of plant-derived compounds that mimic estrogen outweigh the possible health risks. [More]
Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Fulvestrant significantly increases progression-free survival in women with hormone-receptor-positive advanced breast cancer, particularly those with less aggressive lower-volume disease, researchers reported at the ESMO 2016 Congress in Copenhagen [More]
Combination treatment with CDK4/6 inhibitor improves progression-free survival in HR+ breast cancer patients

Combination treatment with CDK4/6 inhibitor improves progression-free survival in HR+ breast cancer patients

The addition of the CDK4/6 inhibitor ribociclib to letrozole therapy significantly improves progression-free survival in postmenopausal women with hormone receptor-positive advanced breast cancer, researchers reported today at the ESMO 2016 Congress in Copenhagen. [More]
Study finds potential for decrease in tobacco use by transgender women who receive hormone therapy

Study finds potential for decrease in tobacco use by transgender women who receive hormone therapy

While there has been much concern about the potential harm from transgender medical intervention (hormone therapy), a new study has found that transgender women who receive hormone therapy are more likely to quit or decrease smoking cigarettes as compared to the general population. [More]
Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found, in animal models of human breast cancer, that inhibiting a single protein restores sensitivity to tamoxifen, a commonly used drug for treatment of some breast cancers. [More]
Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Breast cancer is the most frequently diagnosed cancer among women, with estrogen-receptor-positive (ER+) being the most common type. [More]
Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women

A Mayo Clinic research team has found evidence suggesting that the controversial practice of ovary removal in premenopausal women to prevent ovarian cancer should be discontinued in women who are not at high risk of cancer. [More]
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