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Estrogens are a family of related molecules that stimulate the development and maintenance of female characteristics and sexual reproduction.

The natural estrogens produced by women are steroid molecules, which means that they are derived from a particular type of molecular skeleton containing four rings of carbon atoms, giving the shape shown here. The most prevalent forms of human estrogen are estradiol and estrone. Both are produced and secreted by the ovaries, although estrone is also made in the adrenal glands and other organs.
Two UH scientists named as fellows of AAAS

Two UH scientists named as fellows of AAAS

Two scientists from the University of Houston have been elected as fellows of the American Association for the Advancement of Science. [More]
Cocaine disrupts woman's estrus cycle, may explain sex differences in cocaine addiction

Cocaine disrupts woman's estrus cycle, may explain sex differences in cocaine addiction

Women are more sensitive to the effects of cocaine and more susceptible to cocaine abuse than men. Cocaine's ability to disrupt a woman's estrus cycle may explain the sex differences in cocaine addiction, and new evidence that caffeine may be neuroprotective and able to block cocaine's direct effects on the estrus cycle reveals novel treatment possibilities, according to an article published in Journal of Caffeine Research: The International Multidisciplinary Journal of Caffeine Science, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
Estrogen plays key role in regulating blood pressure, LDL cholesterol levels

Estrogen plays key role in regulating blood pressure, LDL cholesterol levels

What makes some women more susceptible to heart disease than others? To help answer that question, researchers at Western University's Robarts Research Institute have identified that an estrogen receptor, previously shown to regulate blood pressure in women, also plays an important role in regulating low-density lipoprotein (LDL) cholesterol levels. [More]
KU researchers find potential therapeutic target for triple-negative breast cancer

KU researchers find potential therapeutic target for triple-negative breast cancer

A team at the University of Kansas School of Medicine has identified a potential target for treating breast cancer, including a particularly deadly form of the disease. [More]
Aspirin can improve efficacy of schizophrenia treatments

Aspirin can improve efficacy of schizophrenia treatments

A new study shows that some anti-inflammatory medicines, such as aspirin, estrogen, and Fluimucil, can improve the efficacy of existing schizophrenia treatments. This work is being presented at the European College of Neuropsychopharmacology conference in Berlin. [More]
Researchers identify genetic variant in Latina women that protects against breast cancer

Researchers identify genetic variant in Latina women that protects against breast cancer

An international research collaboration led by UC San Francisco researchers has identified a genetic variant common in Latina women that protects against breast cancer. [More]
The Female Athlete Triad: A medical condition in active girls and women

The Female Athlete Triad: A medical condition in active girls and women

Sophie is a 15 year old cross country runner who has a history of a foot stress fracture and shin splints. Often she does not eat prior to her workouts. [More]
Females' natural resistance to bacterial pneumonia is linked to NOS3 enzyme

Females' natural resistance to bacterial pneumonia is linked to NOS3 enzyme

Researchers have linked increased resistance to bacterial pneumonia in female mice to an enzyme activated by the female sex hormone estrogen. [More]
Hormone loss may cause colon cancer, say Thomas Jefferson University researchers

Hormone loss may cause colon cancer, say Thomas Jefferson University researchers

Some cancers, like breast and prostate cancer, are driven by hormones such as estrogen and testosterone, but to date, there are none that are driven by the lack of a hormone. New evidence suggests that human colon cells may become cancerous when they lose the ability to produce a hormone that helps the cells maintain normal biology. If verified by further studies, it suggests that treating patients at high risk for colon cancer by replacing the hormone guanylin could prevent the development of cancer. [More]
Experiments show that 'unsung' cells are crucial to the process of bone loss caused by bone disorder

Experiments show that 'unsung' cells are crucial to the process of bone loss caused by bone disorder

Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns Hopkins researchers. [More]
Endocrine Society issues updated Clinical Practice Guideline on androgens in women

Endocrine Society issues updated Clinical Practice Guideline on androgens in women

The Endocrine Society today issued a Clinical Practice Guideline (CPG) advising against the use of testosterone therapy in healthy women. [More]
Women can now take proactive steps to reduce breast cancer risk

Women can now take proactive steps to reduce breast cancer risk

Now that medical professionals have identified gene mutations that predispose for breast cancer, patients can take proactive steps to reduce their risk. [More]
HerKare opens new location in Mansfield, Texas

HerKare opens new location in Mansfield, Texas

HerKare opens a new location today in Mansfield, Texas. This marks HerKare's third center in Dallas-Fort Worth. HerKare recently expanded to Houston area and continues to accelerate their growth plans, making the treatment of hormonal imbalance in women more convenient. [More]
Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Scientists have discovered a previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs. The researchers say the work reveals new targets for breast cancer therapy and will help doctors predict which patients need the most aggressive treatment. [More]
Epidurals and reduced postpartum depression: an interview with Dr. Zakowski

Epidurals and reduced postpartum depression: an interview with Dr. Zakowski

The “maternity blues”, which resolve within 10 days of giving birth, occurs in up to 80% of new moms. A major depressive episode, by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, is defined as having at least a 2-week period of persistent depressed mood ... [More]
Radiation and endocrine therapy combination may not be necessary for all HR+ breast cancer patients

Radiation and endocrine therapy combination may not be necessary for all HR+ breast cancer patients

Treatment with endocrine therapy and radiation therapy as part of breast conservation is the current standard of care for women with hormone-receptor positive (HR+) invasive breast cancer. A new study by researchers at Fox Chase Cancer Center, however, shows that combination may not be necessary for all patient populations with the disease. [More]
Parous women have higher chance of developing estrogen receptor-negative breast cancer

Parous women have higher chance of developing estrogen receptor-negative breast cancer

Women who have had children (parous women) appear to have an increased risk of developing estrogen receptor-negative breast cancer, the subtype that carries a higher mortality rate and is more common in women of African ancestry. [More]
Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

Postmenopausal women with diverse gut bacteria exhibit a more favorable ratio of estrogen metabolites, which is associated with reduced risk for breast cancer, compared to women with less microbial variation, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). [More]
Sex hormone that helps protect females from stroke may also reduce risk of autism, say scientists

Sex hormone that helps protect females from stroke may also reduce risk of autism, say scientists

The same sex hormone that helps protect females from stroke may also reduce their risk of autism, scientists say. [More]
Scientists find that samples of chocolate purchased in Brazil contain lead and cadmium

Scientists find that samples of chocolate purchased in Brazil contain lead and cadmium

Scientists have found that commercial samples of chocolate purchased in Brazil contain varying levels of lead and cadmium, which can cause health problems, and that those levels are linked to how much cocoa a product contains. [More]