Fibroblast News and Research

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Fibroblasts are connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Osteoarthritis may be treatable and reversible, new study shows

Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible.

31 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Genetically edited chickens show resistance to avian influenza in landmark study

Researchers use CRISPR technology to create chickens resistant to avian influenza, targeting specific genes to inhibit viral replication. The study reveals both the promise and complexities of using genetic editing as a disease control strategy, also shedding light on influenza's adaptability.

11 Oct 2023

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Researchers utilize 3D printing to craft cerebral cortex tissues with organized neurons, offering potential treatments for brain injuries. This novel technique prints neural progenitors in layer-by-layer sequences, aiming for accurate tissue restoration in damaged brains.

8 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

Research provides key insights into the molecular underpinnings of acute liver injury

In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury and its underlying molecular mechanisms.

14 Sep 2023

Cracking the obesity code: The protein leverage hypothesis

The research paper presents an integrative approach to understanding obesity, focusing on the protein leverage hypothesis (PLH) to examine how protein intake affects energy imbalance. It combines insights from nutritional ecology, ecological sciences, and nutritional geometry, suggesting that protein deficiency and amino acid imbalances could drive increased food intake and contribute to obesity.

6 Sep 2023

Aging reorganizes pancreas circadian transcriptome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Reorganization of pancreas circadian transcriptome with aging."

5 Sep 2023

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

A recent study published in Nature Metabolism has revealed the pathogenic mechanism underlying a rare pediatric neurodegenerative disorder known as mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome.

31 Aug 2023

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Researchers investigated whether bone marrow-derived cells contribute to colitis-associated colon cancer.

29 Aug 2023

Ciliopathies: A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals.

25 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

Fibroblast News and Research

Further Reading

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Osteoarthritis may be treatable and reversible, new study shows

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

Genetically edited chickens show resistance to avian influenza in landmark study

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Could plant-based phytonutrients be the secret weapon against obesity?

Research provides key insights into the molecular underpinnings of acute liver injury

Cracking the obesity code: The protein leverage hypothesis

Aging reorganizes pancreas circadian transcriptome

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Ciliopathies: A new understanding of the role of the NSL complex

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

Study explores the effects of different diets on plasma proteins

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

Exploring developmental pathways and disease interactions in nervous and stomatognathic systems

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Scientists develop new technique to "tattoo" living cells with nanomaterials

Lizards' ability to regenerate cartilage could lead to new treatments for osteoarthritis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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