Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

The crucial need for ongoing COVID-19 booster vaccination in vulnerable populations

Researchers investigate the need for prioritizing COVID-19 booster vaccination.

19 Jan 2024

Morphine shows potential as effective cough therapy for pulmonary fibrosis, study finds

The efficacy of the controlled release of low-dose morphine as treatment against that of a placebo in idiopathic pulmonary fibrosis.

18 Jan 2024

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.

16 Jan 2024

£30M clinical study will enhance the understanding of NASH cirrhosis

The most extensive clinical study into liver cirrhosis ever conducted worldwide has been announced by Newcastle University, University of Edinburgh and leading research-driven global biopharmaceutical company, Boehringer Ingelheim.

8 Jan 2024

Comprehensive insights on pathophysiology and clinical management of atrial fibrillation

Atrial fibrillation (AF) is a major global health concern impacting millions and causing symptoms like palpitations, dyspnea, fatigue, dizziness, and chest discomfort.

8 Jan 2024

COMPANION study of digital therapy demonstrates reduced anxiety in patients with pulmonary fibrosis

Vicore Pharma Holding AB (publ), unlocking the potential of a new class of drug candidates, angiotensin II type 2 receptor agonists (ATRAGs), today announced positive results of the COMPANION study (NCT05330312), investigating the efficacy of AlmeeTM, a 9-week digital cognitive behavioral therapy (CBT) accessed through a smartphone or tablet.

8 Jan 2024

Digital CBT intervention reduces anxiety and improves quality of life for pulmonary fibrosis patients

Alex Therapeutics and Vicore Pharma today announced positive results of the COMPANION study, investigating the efficacy of Almee, a 9-week digital cognitive behavioral therapy (CBT) intervention accessed through a smartphone or tablet.

8 Jan 2024

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

5 Jan 2024

Uncovering the true culprit behind nanofiber-induced lung disease

The pathogenic potential of inhaling the inert fibrous nanomaterials used in thermal insulation (such as asbestos or fiberglass) is actually connected not to their chemical composition, but instead to their geometrical characteristics and size.

5 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages.

4 Jan 2024

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against 'superbugs' such as MRSA, a new study shows.

3 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?

2 Jan 2024

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

28 Dec 2023

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Study reveals that cytoglobin (cygb2) plays a crucial role in regulating cilia motility and organ laterality during development, highlighting its importance in NO signaling and cilia function.

19 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

“Forever chemicals” could contribute to cancer metastasis in living organisms

In a new study by researchers at the Yale School of Public Health, two "forever chemicals" spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms.

18 Dec 2023

Two proteins in the blood could predict dengue severity

Scientists and clinicians at Nanyang Technological University, Singapore (NTU Singapore) and the National Centre for Infectious Diseases (NCID) have identified two compounds - sST2 and suPAR - in the blood of dengue patients that could determine if a patient is at risk of severe dengue in the early phases of the disease.

18 Dec 2023

Fibrosis News and Research

Further Reading

The crucial need for ongoing COVID-19 booster vaccination in vulnerable populations

Morphine shows potential as effective cough therapy for pulmonary fibrosis, study finds

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

£30M clinical study will enhance the understanding of NASH cirrhosis

Comprehensive insights on pathophysiology and clinical management of atrial fibrillation

COMPANION study of digital therapy demonstrates reduced anxiety in patients with pulmonary fibrosis

Digital CBT intervention reduces anxiety and improves quality of life for pulmonary fibrosis patients

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Uncovering the true culprit behind nanofiber-induced lung disease

Unlocking the power of diet: How miRNAs influence health and disease

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

Exploring the global health challenge of hepatitis D

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

First new antibiotic class in decades discovered using explainable AI platform

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Autopsy study provides new insights into yellow fever's impact on the heart

“Forever chemicals” could contribute to cancer metastasis in living organisms

Two proteins in the blood could predict dengue severity

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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