Flow Cytometry News and Research

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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

Nitazoxanide shows promise for COVID-19 treatment in animal model

In a recent study posted to the bioRxiv* pre-print server, researchers demonstrated that Nitazoxanide (NTZ), an oral drug, broadly inhibits replication of several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in preclinical models of infection.

13 Feb 2022

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.

9 Feb 2022

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Researchers have investigated the lack of response to treatment in certain multiple sclerosis patients.

9 Feb 2022

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

In a recent research article published in the journal of Science Immunology, a team of researchers from Japan performed longitudinal analysis on the cellular composition of receptor-binding domain (RBD) memory B cell subsets and its antibody binding and neutralizing activity against the Beta, Delta, and Omicron variants following the second dose of a messenger ribonucleic acid (mRNA) vaccine.

8 Feb 2022

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Researchers evaluate how the D614G and P681H mutations alter the attributes of SARS-CoV-2 VOCs.

3 Feb 2022

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

In a new study, researchers explored the systemic immune responses during the acute and convalescent phases of SARS-CoV-2 in children and adults with the same disease severity.

3 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.

28 Jan 2022

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

In a new study, researchers evaluated SARS-CoV-2 vaccination-induced T cell responses cross-recognition among the early and novel SARS-CoV-2 variants.

26 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Scientists assess ACE2 binding and antigenicity of Mu (B.1.621) and A.2.5 spikes

To gain a better understanding of the antigenic properties of Mu and A.2.5 Spikes, Canadian scientists evaluated their capacity to interact with ACE2 and performed binding and neutralization assays with plasma from vaccinated individuals.

18 Jan 2022

PhoreMost expands into new facility at Unity Campus, Cambridge, UK

PhoreMost Ltd today announced it has relocated its headquarters to Unity Campus, a high-specification technology and innovation park.

From PhoreMost 18 Jan 2022

Specific immunoresponse to SARS-CoV-2 in cats and dogs housed with COVID-19 patients

Researchers conducted a detailed epitope mapping of Np and developed an experimental double antigen-based ELISA.

13 Jan 2022

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Researchers screen several systemic autoantibodies to assess their association with the severity of COVID-19.

13 Jan 2022

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

In the present study, researchers isolated an infectious AY.4.2 strain of COVID-19 from the nasopharyngeal swab of a symptomatic individual from the Paris region. Then, they introduced the AY.4.2 signature mutations - T95I, Y145H, and A222V - in an expression plasmid coding the Delta protein to study the function of the AY.4.2 S protein.

13 Jan 2022

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

In a new study, researchers determined the early immune response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during mild coronavirus disease 2019 (COVID-19) in rhesus macaques.

11 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

Flow Cytometry News and Research

Further Reading

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Nitazoxanide shows promise for COVID-19 treatment in animal model

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Memory B cells induced by mRNA vaccine may help generate antibodies against Omicron

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Scientists assess ACE2 binding and antigenicity of Mu (B.1.621) and A.2.5 spikes

PhoreMost expands into new facility at Unity Campus, Cambridge, UK

Specific immunoresponse to SARS-CoV-2 in cats and dogs housed with COVID-19 patients

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

Flow Cytometry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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