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Scientists identify critical biological factor for transforming adult somatic cells into stem cells

Scientists identify critical biological factor for transforming adult somatic cells into stem cells

In a new Cell Reports paper, a team led by John P. Cooke, M.D., Ph.D., of the Houston Methodist Research Institute, has identified and characterized a biological factor critical to the transformation of adult somatic cells (cells that are not sperm or egg cells) into stem cells. [More]
Protease inhibitors may prevent cardiovascular disease risk caused by HIV medications

Protease inhibitors may prevent cardiovascular disease risk caused by HIV medications

According to the World Health Organization, approximately 37 million people are living with HIV. Antiviral medications are used to control the disease and prevent its progression to AIDS. [More]
Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

Researchers at Schepens Eye Research Institute of Massachusetts Eye and Ear have shown a link between mitochondrial dysfunction in corneal endothelial cells and the development of Fuchs' Endothelial Corneal Dystrophy. [More]
Duke researchers identify promising target for renal cell carcinomas

Duke researchers identify promising target for renal cell carcinomas

All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread. [More]
Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin. [More]
Bile pigment may provide natural protection from heart attacks

Bile pigment may provide natural protection from heart attacks

New hope in the fight against cardiovascular disease has arrived, following breakthrough research identifying a pigment in our bile which could protect us. [More]
UGA microbiology researchers identify potential mechanism for neurodegenerative diseases

UGA microbiology researchers identify potential mechanism for neurodegenerative diseases

Microbiology researchers at the University of Georgia studying a soil bacterium have identified a potential mechanism for neurodegenerative diseases. [More]
Sigma 1 receptor appears to play vital role in supporting the retina

Sigma 1 receptor appears to play vital role in supporting the retina

A receptor that is already a target for treating neurodegenerative disease also appears to play a key role in supporting the retina, scientists report. [More]
TSRI study shows antioxidants slow aging process, reduce risk of infection

TSRI study shows antioxidants slow aging process, reduce risk of infection

Scientists from the Florida campus of The Scripps Research Institute have shown how aging cripples the production of new immune cells, decreasing the immune system’s response to vaccines and putting the elderly at risk of infection. [More]
Cognizin citicoline shows promise in patients with bipolar disorder and cocaine dependence

Cognizin citicoline shows promise in patients with bipolar disorder and cocaine dependence

The results of a randomized, double-blind, placebo-controlled clinical trial showed that Cognizin citicoline (Jarrow Formulas) was effective at reducing cocaine use, based on urine drug screens, in patients with bipolar disorder and cocaine dependence. The study, published in the American Journal of Psychiatry in Advance, included a total of 130 outpatients with bipolar I disorder and cocaine dependence, who received either Cognizin citicoline or placebo add-on therapy for 12 weeks. [More]
Lafora rare disease could be aggravated by oxidative stress

Lafora rare disease could be aggravated by oxidative stress

Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for its disposal. Researchers at the University of Valencia have led a study in which they propose that Lafora rare disease could be aggravated by oxidative stress. [More]
Vitamin E helps build strong muscles

Vitamin E helps build strong muscles

Body builders have it right: vitamin E does help build strong muscles, and scientists appear to have figured out one important way it does it. [More]
Northwestern University researchers find safer way to improve surgery outcomes

Northwestern University researchers find safer way to improve surgery outcomes

A Northwestern University research team potentially has found a safer way to keep blood vessels healthy during and after surgery. [More]
Lettuce varieties can have different antioxidant effect

Lettuce varieties can have different antioxidant effect

Lettuce, one of the indispensable vegetables in the Mediterranean diet, is a food that greatly benefits health, mainly because it is rich in antioxidants. But not all lettuce varieties have the same antioxidant effect. [More]
NeoStrata announces launch of SKIN ACTIVE Dermal Replenishment

NeoStrata announces launch of SKIN ACTIVE Dermal Replenishment

NeoStrata Company, Inc., today announced the launch of SKIN ACTIVE Dermal Replenishment, an intense hydrator that delivers a powerful four-pronged anti-aging approach. [More]
Lung cancer rates are lower in higher-elevation counties, new study finds

Lung cancer rates are lower in higher-elevation counties, new study finds

Here's another potential reason to live up in the mountains. Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania. [More]
Atmospheric oxygen may play role in lung carcinogenesis, new study suggests

Atmospheric oxygen may play role in lung carcinogenesis, new study suggests

The ancient physician/alchemist, Paracelsus, said: "The dose makes the poison." According to a new study published in PeerJ, even oxygen may fall prey to the above adage. While essential to human life, aspects of oxygen metabolism may promote cancer. Capitalizing on the inverse relationship of oxygen concentration with elevation, researchers found lower rates of lung cancer at higher elevations, a trend that did not extend to non-respiratory cancers, suggesting that carcinogen exposure occurs via inhalation. [More]
Proper copper levels essential to health of the brain at rest, new study finds

Proper copper levels essential to health of the brain at rest, new study finds

In recent years it has been established that copper plays an essential role in the health of the human brain. Improper copper oxidation has been linked to several neurological disorders including Alzheimer's, Parkinson's, Menkes' and Wilson's. [More]
Mice lacking specific protein live longer lives with fewer age-related illnesses

Mice lacking specific protein live longer lives with fewer age-related illnesses

While developing a new cancer drug, researchers at The Wistar Institute discovered that mice lacking a specific protein live longer lives with fewer age-related illnesses. [More]
Melatonin has protective effects on traumatic brain injury-induced cerebral cortex

Melatonin has protective effects on traumatic brain injury-induced cerebral cortex

Traumatic brain injury can cause post-traumatic neurodegenerations with an increase in reactive oxygen species and reactive oxygen species-mediated lipid peroxidation. Melatonin, a non-enzymatic antioxidant and neuroprotective agent, has been shown to counteract oxidative stress-induced pathophysiologic conditions like cerebral ischemia/reperfusion injury, neuronal excitotoxicity and chronic inflammation. [More]
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