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Retrospective study finds overuse of colonoscopies for colorectal cancer screening, surveillance

Retrospective study finds overuse of colonoscopies for colorectal cancer screening, surveillance

A retrospective study led by researchers at Brigham and Women's Hospital (BWH), has found an overuse of colonoscopies for colorectal cancer screening and surveillance. [More]
Viewpoints: Ezekiel Emanuel's choice of an age to die; new enrollment numbers still confusing

Viewpoints: Ezekiel Emanuel's choice of an age to die; new enrollment numbers still confusing

Seventy-five. That's how long I want to live: 75 years. This preference drives my daughters crazy. It drives my brothers crazy. My loving friends think I am crazy. They think that I can't mean what I say; that I haven't thought clearly about this, because there is so much in the world to see and do. To convince me of my errors, they enumerate the myriad people I know who are over 75 and doing quite well. They are certain that as I get closer to 75, I will push the desired age back to 80, then 85, maybe even 90. I am sure of my position. [More]
Cyclothymic temperament linked to suicidality

Cyclothymic temperament linked to suicidality

The presence of a cyclothymic temperament in inpatients with bipolar disorder may indicate a high likelihood of hopelessness and suicidality, report researchers. [More]
Bayer, Orion begin patient enrollment in ODM-201 Phase III trial for castration-resistant prostate cancer

Bayer, Orion begin patient enrollment in ODM-201 Phase III trial for castration-resistant prostate cancer

Bayer HealthCare and Orion Corporation, a pharmaceutical company based in Espoo, Finland, have begun to enroll patients in a Phase III trial with ODM-201, an investigational oral androgen receptor inhibitor in clinical development. [More]
AbbVie’s Phase 3 pivotal study shows HUMIRA is effective in reducing symptoms in HS

AbbVie’s Phase 3 pivotal study shows HUMIRA is effective in reducing symptoms in HS

AbbVie today announced results from a Phase 3 pivotal study demonstrating that HUMIRA® (adalimumab) is effective in reducing common clinical signs and symptoms in moderate-to-severe hidradenitis suppurativa (HS), specifically the number of abscesses and inflammatory nodules. [More]
Brain imaging could assist bipolar depression diagnosis

Brain imaging could assist bipolar depression diagnosis

Researchers have identified structural brain differences that could help to distinguish patients with unipolar and bipolar depression. [More]
Study finds 1/4 of errors made in medical publications

Study finds 1/4 of errors made in medical publications

A new Saint Louis University study finds one fourth of errors made in medical publications can change the way data are interpreted. [More]
Study suggests phages are sophisticated bacterial predators and can prevent infections

Study suggests phages are sophisticated bacterial predators and can prevent infections

In the battle between our immune systems and cholera bacteria, humans may have an unknown ally in bacteria-killing viruses known as phages. [More]
NIH-funded study explores how thalamic reticular nucleus influences consciousness

NIH-funded study explores how thalamic reticular nucleus influences consciousness

Ever wonder why it's hard to focus after a bad night's sleep? Using mice and flashes of light, scientists show that just a few nerve cells in the brain may control the switch between internal thoughts and external distractions. [More]
Articles describe barriers to, potential of greater adoption of complex care management

Articles describe barriers to, potential of greater adoption of complex care management

The care of patients with complex medical needs is widely regarded as one of the key factors driving increased U.S. health costs, and it is generally accepted that 10 to 15 percent of Medicare patients account for 65 to 75 percent of all Medicare spending. [More]
Kootenai Health joins Mayo Clinic Care Network as new member

Kootenai Health joins Mayo Clinic Care Network as new member

Kootenai Health and Mayo Clinic leaders today announced Kootenai Health as a member of the Mayo Clinic Care Network, a national network of like-minded organizations that share a commitment to better serving patients and their families. [More]
‘Soft’ bipolar spectrum disorders differ from depression

‘Soft’ bipolar spectrum disorders differ from depression

The neurocognitive function of patients with major depression who fall into the “soft” bipolar spectrum resembles that of patients with bipolar II disorder rather than those with unipolar depression, say researchers. [More]
GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

GSK today announced that once-weekly Tanzeum (albiglutide), a prescription injectable treatment for type 2 diabetes in adults, as an adjunct to diet and exercise, is now available in pharmacies throughout the U.S. [More]
Researchers one step closer to finding treatment for Alzheimer's, other forms of dementia

Researchers one step closer to finding treatment for Alzheimer's, other forms of dementia

There is no cure for Alzheimer's disease and other forms of dementia, but the research community is one step closer to finding treatment. [More]
Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Bayer HealthCare and Onyx Pharmaceuticals Inc., an Amgen subsidiary, today announced that an investigational Phase 3 trial of NEXAVAR (sorafenib) tablets in patients with advanced breast cancer did not meet its primary endpoint of improving progression-free survival (PFS). [More]
Common genetic variation in gene may modify cardiovascular benefit of aspirin

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease. [More]
Researchers use simple tactics to reduce unnecessary blood tests, health care spending

Researchers use simple tactics to reduce unnecessary blood tests, health care spending

Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the number of unnecessary blood tests to assess symptoms of heart attack and chest pain and to achieve a large decrease in patient charges. [More]
Autistic-like behaviors linked with disruption of Adenomatous Polyposis Coli gene

Autistic-like behaviors linked with disruption of Adenomatous Polyposis Coli gene

Autistic-like behaviors and decreased cognitive ability may be associated with disruption of the function of the Adenomatous Polyposis Coli (APC) gene. [More]
Tufts researchers gain new insight into protein associated with bipolar disorder

Tufts researchers gain new insight into protein associated with bipolar disorder

Researchers from Tufts have gained new insight into a protein associated with bipolar disorder. The study, published in the June 3 issue of Science Signaling, reveals that calcium channels in resting neurons activate the breakdown of Sp4, which belongs to a class of proteins called transcription factors that regulate gene expression. [More]
FDA approves Takeda's Entyvio for severe active ulcerative colitis and Crohn's disease

FDA approves Takeda's Entyvio for severe active ulcerative colitis and Crohn's disease

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., has announced that the United States (U.S.) Food and Drug Administration (FDA) simultaneously approved a new biologic therapy, Entyvio™ (vedolizumab), for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD). [More]