Genetic News and Research

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Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

What are the effects of heavy metals on the risk of endometriosis in reproductive-age women?

The current study focuses on lead, arsenic, cadmium, and mercury, all of which have been linked to the disordered functioning of the human reproductive system.

26 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

Cancer survival rate rises in the US

In a recent article by the American Association for Cancer Research (AACR), the researchers highlighted basic, translational, and clinical cancer research and cancer-related population sciences in the 12th edition of its annual Cancer Progress Report.

25 Sep 2022

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Tiny nets woven from DNA strands can ensnare the spike protein of the virus that causes COVID-19, lighting up the virus for a fast-yet-sensitive diagnostic test – and also impeding the virus from infecting cells, opening a new possible route to antiviral treatment, according to a new study.

23 Sep 2022

Studies explore how differences in skin composition may lead to dermatological conditions

Why are certain body parts more prone to skin diseases than others? Two new UC Davis Health studies explored how differences in skin composition may lead to dermatological conditions, such as psoriasis and atopic dermatitis.

23 Sep 2022

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

The team of Prof. Alain Vanderplasschen, virologist and immunologist at the University of Liège, has published an article in the journal Nucleic Acids Research, reporting ten years of research on how a carp virus has been using a protein domain called Zalpha (Zα) to inhibit the defense mechanisms of the host cell.

23 Sep 2022

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests.

23 Sep 2022

Study finds strong links between certain gut bacteria and small molecules in the blood

There are strong links between bacteria living in the gut and the levels of small molecules in the blood known as metabolites.

23 Sep 2022

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

22 Sep 2022

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).

22 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus -; the tube connecting the throat to the stomach.

22 Sep 2022

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Is SARS-CoV-2 hiding in your fat cells? A study by Stanford Medicine investigators shows that SARS-CoV-2 can infect human fat tissue.

22 Sep 2022

Researchers receive $3.4 million NIH grant to assess soccer's tradeoffs with respect to brain health

More than 25 million Americans play soccer, the world's most popular sport. Soccer significantly benefits brain health by boosting aerobic capacity and oxygen and blood flow to the brain, but it also has a downside: Recent studies show that highly repetitive heading of the ball is associated with structural brain changes and worse cognitive performance similar to brain damage caused by concussion.

22 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

Genetic News and Research

Common germline variants of APOE contribute to differential COVID-19 outcomes

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

What are the effects of heavy metals on the risk of endometriosis in reproductive-age women?

A good night's sleep promotes immunity

Cancer survival rate rises in the US

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Studies explore how differences in skin composition may lead to dermatological conditions

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Shape-shifting fat cells offer a fertile soil for breast tumor invasion and growth

Study finds strong links between certain gut bacteria and small molecules in the blood

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Researchers receive $3.4 million NIH grant to assess soccer's tradeoffs with respect to brain health

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

Sequencing & Genomics: Elevating Science and Healthcare eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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