Glomerulus News and Research

RSS

Glomeruli are at the heart of renal function, and yet are only part of an intact nephron. They are of irreplaceable value in maintaining homeostasis.

Researchers find new clues to understanding the progression of primary membranous nephropathy

No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood.

9 Apr 2024

High-impact clinical trial results to be presented at ASN Kidney Week 2023

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2023 November 1–November 5.

3 Nov 2023

Scientists discover new mechanism for kidney cell renewal

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and remain functioning and healthy.

14 Jul 2023

POSTECH team engineers an artificial kidney for early detection of adverse drug reactions

The kidney plays a vital role in maintaining homeostasis within the body by eliminating toxic and superfluous substances in the bloodstream, including waste generated during metabolic processes, through urine.

31 Mar 2023

Scientists discover new way to reduce progression of diabetic kidney disease

A new way to reduce progression of diabetic kidney disease, affecting 40% of people with diabetes, has been discovered by scientists.

7 Feb 2023

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Now, a new study posted to the bioRxiv* server by scientists from the University of Washington explores the use of NanoString’s GeoMx digital spatial profiling (DSP) to investigate CG caused by HIV and SARS-Cov-2 infections.

14 Sep 2021

Study could pave way for new therapies for kidney disease

Our kidneys are charged with the extraordinary task of filtering about 53 gallons of fluid a day, a process that depends on podocytes, tiny, highly specialized cells in the cluster of blood vessels in the kidney where waste is filtered that are highly vulnerable to damage.

5 May 2021

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome, reveals study

An international research collaboration, including Professor IIJIMA Kazumoto et al. (of the Department of Pediatrics, Kobe University Graduate School of Medicine) has revealed that NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children.

3 Jul 2020

Cell signaling pathway could treat chronic kidney disease and other medical conditions

Scientists have discovered an important cell signaling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.

16 Jun 2020

Empagliflozin reduces CKD progression in type 2 diabetics with cardiovascular disease

Empagliflozin (EMPA), a selective inhibitor of sodium/glucose cotransporter 2 (SGLT2 inhibitors, "gliflozines"), reduces CKD progression in type 2 diabetics (T2D) with cardiovascular disease, presumably by lowering intraglomerular pressure.

9 Jun 2020

Machine learning may augment diagnostics of kidney disease

Two new studies reveal that modern machine learning--a branch of artificial intelligence in which systems learn from data, identify patterns, and make decisions--may augment traditional diagnostics of kidney disease. The findings appear in an upcoming issue of JASN.

6 Sep 2019

Scientists demonstrate an in vitro kidney model

Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease are characterized by a reduced ability to perform this essential function.

14 Aug 2019

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

25 Mar 2019

Scientists identify 'skeleton key' for congenital kidney disease research

Scientists in Japan have found a 'skeleton key' for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully developed kidney tissue that exhibits the early stages of congenital kidney disease.

31 Oct 2018

Glomerulus News and Research

Further Reading