Glycolysis News and Research

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Glycolysis is a series of reactions that helpextract energy from glucose. This is an ancient pathway of metabolism that is present in the majority of living organisms today. It is the foundation of both aerobic and anaerobic cellular respiration. It takes place in the cytosol of a cell and is the foundation of both aerobic and anaerobic cellular respiration.

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the September issue of The Journal of Nuclear Medicine.

27 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

Study reveals potential targets to improve the treatment of myeloma

A ground-breaking study by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has revealed crucial insights into the role of the histone methyltransferase NSD2 and its epigenetic target PKCα in causing t(4;14) translocated multiple myeloma (MM), a high-risk subtype of blood cancer, to be more aggressive and resistant to treatment.

12 Sep 2023

High dietary intake of added sugars could increase the risk of coronary heart disease

The associations between individual dietary sugar types and the risk of coronary heart disease.

6 Sep 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Researchers examined current evidence on the reasons and implications of pancreatic beta-cell failure.

3 Aug 2023

New method allows the discovery of specific inhibitors of lactate transporter

Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate transporter associated with cancer and other disease areas.

28 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Researchers develop first therapy of its kind to treat cisplatin-resistant prostate cancer

Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -; cisplatin.

12 Jul 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Simple juice concentrate from the Japanese plum may reduce cardiovascular disease risk

More than 122 million Americans – about half of the U.S. population ages 20 and older – have high blood pressure, referred to medically as hypertension.

13 Jun 2023

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

In a review article published in the journal Signal Transduction and Targeted Therapy, scientists have discussed host metabolic alteration triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its effect on disease severity.

9 Jun 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Glycolysis News and Research

Further Reading

Discovery of a novel therapeutic target for pancreatic cancer

Could plant-based phytonutrients be the secret weapon against obesity?

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

Researchers identify a rare cause of male infertility and discover a potential cure

Study reveals potential targets to improve the treatment of myeloma

High dietary intake of added sugars could increase the risk of coronary heart disease

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

New method allows the discovery of specific inhibitors of lactate transporter

Aerobic glycolysis essential for eye development in mammals, study finds

Researchers develop first therapy of its kind to treat cisplatin-resistant prostate cancer

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Simple juice concentrate from the Japanese plum may reduce cardiovascular disease risk

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Surviving without glucose: uridine-derived ribose as an alternative energy source

Indirect inhibitors of cellular respiration for treatment of glioblastoma

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

Dietary dicarbonyls may improve insulin sensitivity and reduce type 2 diabetes risk

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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