Growth Hormone News and Research

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Growth hormone (GH) is a protein-based peptide hormone. It stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland.

Men who survive childhood leukemia have lower bone mineral density

Men who survived childhood leukemia treatment into adulthood were more likely to have low bone mineral density than other adults their age, putting them at risk of osteoporosis and bone fractures, according to a new study.

3 Dec 2008

IGF-1 not beneficial for amyotrophic lateral sclerosis

A growth hormone that had shown some promise for treating people with amyotrophic lateral sclerosis (ALS) showed no benefit in a new study published in the November 25, 2008, issue of Neurology , the medical journal of the American Academy of Neurology.

24 Nov 2008

Study looks at investigational compound MK-677 in Alzheimer's disease

A new study shows that a drug that increases the release of growth hormone failed to slow the rate of progression of Alzheimer's disease in humans.

17 Nov 2008

Growth hormone treatment helps short children grow up

Growth hormone treatment may significantly increase final height in children diagnosed with short stature, even in cases where the child is not growth hormone deficient, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

7 Nov 2008

Needle-free injection device approved in Europe and Australia

Antares Pharma, Inc. today announced that its license partner, Ferring Pharmaceuticals has received additional regulatory approvals in Europe and Australia for use of Antares' needle-free injection devices with its human growth hormone (hGH), Zomacton.

6 Nov 2008

Investigational drug, MK-677 shows promise for reducing age-related frailty

Researchers at the University of Virginia Health System report that a daily single oral dose of an investigational drug, MK-677, increased muscle mass in the arms and legs of healthy older adults without serious side effects, suggesting that it may prove safe and effective in reducing age-related frailty.

5 Nov 2008

Anti-frailty pill for seniors in the pipeline

An 'anti-frailty' pill for seniors could be in the pipeline - the pill which increases muscle mass in arms and legs of older adults is the brainchild of researchers at the University of Virginia Health System.

5 Nov 2008

New therapeutic platform technology tackles major diseases

A spin out company from basic structural biology, Asterion Ltd., has led to new technology that provides a way of creating therapeutic proteins to tackle major diseases such as cancer, diabetes and infertility.

8 Aug 2008

Genetic biomarker linked to subcutaneous growth hormone dose-response

The interindividual variability of response to subcutaneously applied protein-based drugs remains poorly understood. However, defining genetic markers that can be associated with biological effects of such drugs may improve the understanding of individual variability of response and even drug resistance.

6 Aug 2008

Growth hormone reduces abdominal fat, cardiovascular risk in HIV patients on antiviral therapy

Low-dose growth hormone treatment reduced abdominal fat deposits and improved blood pressure and triglyceride levels in a group of patients with HIV lipodystrophy, a condition involving the redistribution of fat and other metabolic changes in patients receiving combination drug therapy for HIV infection.

3 Aug 2008

New research shows that adrenal nodules not being adequately evaluated

A new study published in Endocrine Practice found that a substantial percentage of patients with nodules, or growths, in their adrenal glands were not being properly evaluated by physicians.

2 Jul 2008

Growth hormone FGF21's link to starvation may be clue to increasing life span, researchers find

Researchers at UT Southwestern Medical Center have determined that starvation blocks the effects of growth hormone via a mechanism that may have implications in treating diabetes and extending life span.

30 Jun 2008

Discovery of new biomarkers for growth hormone - potential for detecting growth hormone abuse

Researchers have found potential new biomarkers for growth hormone, which they say could help the sports community in detecting growth hormone abuse. The results of the animal study will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.

17 Jun 2008

Scientists identify proteins in mice that might act as biomarkers for growth hormone

Ohio University scientists have identified several proteins in mice that might act as biomarkers for growth hormone. The research could be the first step to finding a more reliable way to detect recombinant human growth hormone (rhGH), which some athletes and teenagers use illegally to boost muscle and reduce fat.

17 Jun 2008

Boys are twice as likely as girls in the U.S. and Asia to receive growth hormone

Boys are twice as likely as girls in the U.S. and Asia (mostly Japan) to receive recombinant human growth hormone (rhGH) for growth hormone deficiency, illnesses that affect height, and short stature of a non-medical nature.

17 Apr 2008

Anticipation of laughter reduces levels of stress hormones

In 2006 researchers investigating the interaction between the brain, behavior, and the immune system found that simply anticipating a mirthful laughter experience boosted health-protecting hormones.

8 Apr 2008

De-marrowing helps bones mend faster

Could you strengthen bones and speed up recovery after fractures and breaks simply by removing some bone marrow with a syringe?

3 Apr 2008

Genetic mutations involved in IGF-I signaling pathway influence life span

Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found.

6 Mar 2008

New clinician's guide to prevention and treatment of osteoporosis

The National Osteoporosis Foundation has released its new "Clinician's Guide to Prevention and Treatment of Osteoporosis" which represents a new era for healthcare providers in the evaluation and treatment of people with low bone mass or osteoporosis.

22 Feb 2008

New proof-of-principle findings that thymic involution can be reversed in humans

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) and the University of California, San Francisco (UCSF) have found that therapy can be used to stimulate the production of vital immune cells, called "T- cells," in adults with HIV infection.

21 Feb 2008