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Novel influenza A (H1N1) is a new flu virus of swine origin that was first detected in Mexico and the United States in March and April, 2009. The first novel H1N1 patient in the United States was confirmed by laboratory testing at CDC on April 15, 2009. The second patient was confirmed on April 17, 2009. It was quickly determined that the virus was spreading from person-to-person. On April 22, CDC activated its Emergency Operations Center to better coordinate the public health response. On April 26, 2009, the United States Government declared a public health emergency.

It’s thought that novel influenza A (H1N1) flu spreads in the same way that regular seasonal influenza viruses spread; mainly through the coughs and sneezes of people who are sick with the virus.
New tool to identify air travelers with infectious disease developed

New tool to identify air travelers with infectious disease developed

Researchers have developed a simple new tool to help governments worldwide decide whether to screen airplane passengers leaving or arriving from areas of infectious disease outbreaks. [More]
More research needed to measure impact of co-infections on hospital admission

More research needed to measure impact of co-infections on hospital admission

A study at Rhode Island Hospital has found that despite complications, patients co-infected with the pandemic 2009-2010 influenza A H1N1 (pH1N1) and a second respiratory virus were not associated with worse outcomes or admission to the hospital's intensive care unit. [More]
Medicago, IDRI to present Phase I clinical results of H5N1 vaccine at World Vaccine Congress

Medicago, IDRI to present Phase I clinical results of H5N1 vaccine at World Vaccine Congress

IDRI, a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today announced that they will be presenting positive interim Phase I clinical results for their H5N1 Avian Influenza VLP vaccine candidate "H5N1 vaccine" at the World Vaccine Congress. [More]
New national study examines marijuana use and prescription drug misuse

New national study examines marijuana use and prescription drug misuse

Individuals who use marijuana recreationally are more likely to misuse other drugs, including pain-controlling, but potentially addictive narcotics, sedatives and other prescription medications, than individuals who do not use marijuana, according to a new national study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services. [More]
Anti-vaccination messages spread more easily than positive ones on Twitter, researchers find

Anti-vaccination messages spread more easily than positive ones on Twitter, researchers find

On Twitter, a popular microblogging and social-networking service, statements about vaccines may have unexpected effects -- positive messages may backfire, according to a team of Penn State University researchers led by Marcel Salath-, an assistant professor of biology. [More]
BioCryst Pharmaceuticals receives preliminary comment letter from FDA on peramivir

BioCryst Pharmaceuticals receives preliminary comment letter from FDA on peramivir

BioCryst Pharmaceuticals, Inc. today announced that it received a preliminary comment letter from the U.S. Food & Drug Administration that outlines a pathway by which BioCryst could file a New Drug Application seeking regulatory approval of intravenous (i.v.) peramivir. [More]
Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

The over-the-counter anti-inflammatory drug naproxen may also exhibit antiviral activity against influenza A virus, according to a team of French scientists. The finding, the result of a structure-based investigation, is published online ahead of print in the journal Antimicrobial Agents and Chemotherapy. [More]
Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for stimulating protective immune responses following seasonal influenza vaccinations. [More]
UCLA researchers predict hotspots for future outbreaks of influenza virus

UCLA researchers predict hotspots for future outbreaks of influenza virus

This year's unusually long and rocky flu season would be nothing compared to the pandemic that could occur if bird flu became highly contagious among humans, which is why UCLA researchers and their colleagues are creating new ways to predict where an outbreak could emerge. [More]
H1N1 flu vaccination associated with small excess risk of acquiring Guillain-Barré syndrome, but benefits outweigh risks

H1N1 flu vaccination associated with small excess risk of acquiring Guillain-Barré syndrome, but benefits outweigh risks

A meta-analysis of safety data gathered during the 2009 H1N1 vaccination programme in the US has established that the vaccination was associated with a small excess risk – about 1.6 extra cases per one million people vaccinated – of acquiring Guillain-Barré syndrome, a disorder of the nervous system which can result in temporary or more long-lasting paralysis and infrequently death. The authors conclude that the benefits of the 2009 H1N1 vaccination campaign greatly outweighed the risks. [More]

IL-22 plays critical role in normal lung repair following influenza infection

Once the initial episode of influenza has passed, the chronic effects tend to be overlooked. The results of a new study indicate that the cytokine interleukin-22 (IL-22) plays a critical role in normal lung repair following influenza infection. This study is published in the April 2013 issue of the American Journal of Pathology. [More]
Marked seasonal variation in COPD exacerbations

Marked seasonal variation in COPD exacerbations

Patients with chronic obstructive pulmonary disease are significantly more likely to experience exacerbations during the winter than summer months, research shows. [More]
Nursing home patients with pneumonia may need viral screening

Nursing home patients with pneumonia may need viral screening

Viral testing should be carried out among all older individuals who have been admitted to hospital for nursing home-acquired pneumonia, recommend researchers. [More]
Influenza vaccine linked to narcolepsy in children in England

Influenza vaccine linked to narcolepsy in children in England

Researchers have found an increased risk for narcolepsy in children who received the swine flu vaccination in England. [More]
NanoViricides retires Series C Convertible Preferred Stock previously purchased by Seaside

NanoViricides retires Series C Convertible Preferred Stock previously purchased by Seaside

NanoViricides, Inc., announced today that it has retired the remainder of the Series C Convertible Preferred Stock previously purchased by Seaside 88, LP, with a cash payment. [More]

Researchers identify new function for matriptase enzyme

Dr. Martin Richter (pharmacology), investigator with the Centre de recherche clinique Étienne-Le Bel (CRCELB) at the Centre hospitalier universitaire de Sherbrooke (CHUS) and professor in the Faculty of Medicine and Health Sciences of the Université de Sherbrooke (UdeS), and his collaborators have identified a new function of the enzyme matriptase, present in the human respiratory system, that can activate a viral protein involved in infections caused by the H1N1 influenza (or flu) virus. [More]

New molecular compounds can kill the influenza virus

Simon Fraser University virologist Masahiro Niikura and his doctoral student Nicole Bance are among an international group of scientists that has discovered a new class of molecular compounds capable of killing the influenza virus. [More]

University of Louisville research team explores H1N1 outbreak

Just the mention of H1N1 can conjure up images of long lines of people waiting to be vaccinated, news reports of the severity of the pandemic and the count of the number of people who perished from the 2009-10 outbreak. However, some positives are coming forward. [More]

Study evaluates effectiveness of H1N1 vaccine in pregnant women against adverse infant outcomes

Pregnant women who received the H1N1 influenza vaccine during the 2009 pandemic were less likely to have premature babies, and their babies weighed more on average. [More]
New research focuses on rapid identification of disease outbreaks

New research focuses on rapid identification of disease outbreaks

EcoHealth Alliance, the nonprofit organization that focuses on local conservation and global health issues, announced new research focused on the rapid identification of disease outbreaks in the peer reviewed publication, Journal of the Royal Society Interface. [More]