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Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV).

This condition progressively reduces the effectiveness of the immune system and leaves individuals susceptible to opportunistic infections and tumors. HIV is transmitted through direct contact of a mucous membrane or the bloodstream with a bodily fluid containing HIV, such as blood, semen, vaginal fluid, preseminal fluid, and breast milk.
Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS. [More]
New microfluidic biosensor can identify white blood cells quickly for AIDS diagnosis

New microfluidic biosensor can identify white blood cells quickly for AIDS diagnosis

Researchers from the University of Illinois at Urbana-Champaign have developed a highly sensitive biosensor based on a differential immuno-capture technology that can detect sub-populations of white blood cells. As part of a small, disposable biochip, the microfluidic biosensor can count CD4+/CD8+ T cells quickly and accurately for AIDS diagnosis in the field. [More]
Negative cancer clinical trials have long-term impact on research

Negative cancer clinical trials have long-term impact on research

Cancer clinical trials with negative results don't make an immediate splash in the scientific literature, but they do have a long-term impact on cancer research, according to a new study by SWOG, the federally funded international clinical trials network. [More]
VIGH study seeks to eliminate mother-to-child transmission of HIV in Africa

VIGH study seeks to eliminate mother-to-child transmission of HIV in Africa

Mother-to-child transmission of the human immunodeficiency virus (HIV), which causes AIDS, is still a major problem in resource-limited, rural areas of the world where health care providers are scarce. [More]
Scientists track rare potent antibodies in HIV-infected individual

Scientists track rare potent antibodies in HIV-infected individual

One of the most crucial and elusive goals of an effective HIV vaccine is to stimulate antibodies that can attack the virus even as it relentlessly mutates. [More]
Targeted Case Management has major impact on HIV-positive patients

Targeted Case Management has major impact on HIV-positive patients

Providing comprehensive, holistic case management to people dealing with multiple comorbid conditions, including HIV, can yield tangible health improvements and long-term cost savings, according to a new study released by Amida Care, a New York City nonprofit health plan, and ACRIA, an HIV/AIDS research organization. [More]
Sangamo presents immunological data from SB-728-T HIV clinical study at CROI 2016

Sangamo presents immunological data from SB-728-T HIV clinical study at CROI 2016

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced the presentation of immunological data from the Company's clinical trials of SB-728-T, a ZFP Therapeutic designed to provide functional control of HIV. [More]
ARV drug atazanavir may have significant effects on infant development

ARV drug atazanavir may have significant effects on infant development

The antiretroviral (ARV) drug atazanavir—sometimes included in treatments to prevent mother-to-child HIV transmission during pregnancy—may have small but significant effects on infant development, reports a study in the journal AIDS, official journal of the International AIDS Society. [More]
Dapivirine ring can help prevent HIV-1 infection in women

Dapivirine ring can help prevent HIV-1 infection in women

In an important scientific achievement for women's health, two large Phase III clinical trials -- The Ring Study and ASPIRE -- have shown that a monthly vaginal ring containing the antiretroviral drug (ARV) dapivirine can safely help prevent HIV-1 infection in women. [More]
Researchers devise new approach to improve current T-cell therapy methods

Researchers devise new approach to improve current T-cell therapy methods

T-cell therapy, a form of immunotherapy that uses a patient's own immune cells to attack their cancer, has been making waves recently. The "living" therapy involves engineering the patient's T cells in the laboratory to carry new proteins that guide the immune cells directly to tumor cells, allowing the engineered T cells to attack and kill the cancer. [More]
Study identifies new mechanism for controlling HIV replication

Study identifies new mechanism for controlling HIV replication

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. [More]
Researchers identify new group of powerful Ebola-fighting antibodies

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus. [More]
Mylan announces FDA's acceptance of ANDA filing for generic Advair Diskus

Mylan announces FDA's acceptance of ANDA filing for generic Advair Diskus

Mylan N.V. today announced that its abbreviated new drug application (ANDA) for fluticasone propionate 100, 250, 500 mcg and salmeterol 50 mcg inhalation powder has been accepted for filing by the U.S. Food and Drug Administration. [More]
Researchers identify how Toxoplasma parasite crosses blood-brain barrier

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

An estimated 30 percent of the world's population is chronically infected with the parasite Toxoplasma gondii. Most people live with the infection without noticeable effect, but it can be life-threatening for people with suppressed immune systems, such as people on cancer therapies or who have HIV/AIDS. [More]
Implementing harm reduction interventions among PWID to prevent HIV epidemic in Colombia

Implementing harm reduction interventions among PWID to prevent HIV epidemic in Colombia

In the early 1990s, drug production in Colombia diversified to include heroin as well as cocaine, and since then the country's role in the heroin trade has substantially increased. According to the United Nations Office on Drugs and Crime, Colombia produced approximately 70 to 100 metric tons of heroin between 1998 and 2004. Studies have found an increase in local heroin use since the mid-1990s. This is a strong cause for concern, given the potential for HIV to spread through networks of injection drug users and disseminate to the general public. [More]
Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers have been named winners of the 2016 Elsevier Foundation Awards for Early Career Women Scientists in the Developing World, in recognition of research that has strong potential health and economic benefits. [More]
Insulin remains expensive and beyond the reach of many diabetics worldwide

Insulin remains expensive and beyond the reach of many diabetics worldwide

More than 90 years after it was first discovered, and despite being listed as an essential medicine by the World Health Organization (WHO) since 2007, the lifesaving diabetes drug, insulin, remains very expensive and beyond the reach of many people with type 1 and 2 diabetes who need it globally, say leading experts writing in The Lancet Diabetes & Endocrinology journal. [More]
FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced that the U.S. Food and Drug Administration has cleared the Company's Investigational New Drug (IND) application for SB-318, a single treatment strategy intended to provide a life-long therapy for Mucopolysaccharidosis Type I (MPS I). [More]
Study examines links between spending on social services and AIDS deaths in U.S.

Study examines links between spending on social services and AIDS deaths in U.S.

Despite considerable advances in the prevention and treatment of HIV/AIDS over the past 30 years, HIV infection rates have remained stagnant in the United States for the past decade. A study by researchers at the Yale Global Health Leadership Institute examines links between spending on social services and public health and AIDS deaths in the United States. [More]
Cistus extracts attack HIV and Ebola viruses

Cistus extracts attack HIV and Ebola viruses

Scientists at the Helmholtz Zentrum München discover that extracts of the medicinal plant Cistus incanus (Ci) prevent human immunodeficiency viruses from infecting cells. Active antiviral ingredients in the extracts inhibit docking of viral proteins to cells. Antiviral activity of Cistus extracts also targets Ebola- and Marburg viruses. [More]
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