Heart Failure News and Research RSS Feed - Heart Failure News and Research

Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.
Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Why do women have lower rates of heart failure than men for most of their lives? University of Guelph researchers have uncovered a possible clue - an actin binding protein called "CapZ" that also protects against heart attacks. [More]
Study underscores importance of targeting prevention efforts at preclinical HF stages

Study underscores importance of targeting prevention efforts at preclinical HF stages

According to a recent study of Framingham Study participants, nearly 60 percent of people have prevalent preclinical heart failure (HF) stages A and B. Heart failure occurs when the heart muscle is weakened and cannot pump enough blood to meet the body's needs for blood and oxygen. [More]
Loyola among first health systems to offer absorbable stent to heart patients

Loyola among first health systems to offer absorbable stent to heart patients

Loyola Medicine will be among the first health systems in the country to offer heart patients a new stent that is absorbed by the body once it has served its purpose. [More]
European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year. [More]
Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses. [More]
Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics, a biopharmaceutical company with the mission of developing new therapies for unmet medical needs in the field of cardiovascular diseases, today announced the initiation of its Phase IIa multicentric clinical trial of GQC101, entitled QUID HF (QUantum Genomics Incremental Dosing in Heart Failure), for the treatment of patients with chronic heart failure. The first three clinical centres of the European trial have been opened in France and Norway. [More]
Anaemia in heart failure may impact prognosis

Anaemia in heart failure may impact prognosis

Anaemia is common in patients with heart failure, regardless of the underlying phenotype, and is often associated with iron deficiency, UK researchers report. [More]
Circulating angiogenic factor shows PAH biomarker potential

Circulating angiogenic factor shows PAH biomarker potential

Hepatoma-derived growth factor predicts disease severity and survival in patients with pulmonary arterial hypertension, showing some possible clinical advantages over N-terminal pro-brain natriuretic peptide, researchers report. [More]
'Comprehensive' management approach needed for AF

'Comprehensive' management approach needed for AF

Death is a bigger risk than stroke among patients with atrial fibrillation, particularly during the first 4 months after diagnosis, research shows. [More]
Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the University Clinic of Düsseldorf have established an in vitro model system for investigating nonalcoholic fatty liver disease (NAFLD). [More]
Breakthrough research could lead to new drugs to improve heart attack outcomes

Breakthrough research could lead to new drugs to improve heart attack outcomes

A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks. [More]
Excessive weight at young age increases risk of heart failure

Excessive weight at young age increases risk of heart failure

It comes down to starting healthy habits early. Fortunately, it's never too late to adopt a healthier lifestyle, and losing weight is great for reducing your risk of heart attack. But you can still be at a higher risk for other heart problems if you're late in changing your habits. [More]
MOOD-HF supports lack of antidepressant efficacy in HF patients

MOOD-HF supports lack of antidepressant efficacy in HF patients

Escitalopram influences neither depressive symptoms nor medical outcomes when compared with placebo in patients with heart failure and depression, show the MOOD-HF findings. [More]
New electric mesh device wraps around the heart to deliver electrical impulses

New electric mesh device wraps around the heart to deliver electrical impulses

A research team led by investigators at Beth Israel Deaconess Medical Center and Seoul National University has developed a new electric mesh device that can be wrapped around the heart to deliver electrical impulses and thereby improve cardiac function in experimental models of heart failure, a major public health concern and leading cause of mortality and disability. [More]
Pioglitazone effective in diabetes patients with NASH

Pioglitazone effective in diabetes patients with NASH

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows. [More]
Elevated troponin I should not rule out donor hearts

Elevated troponin I should not rule out donor hearts

Donor cardiac troponin I level is not associated with intermediate-term mortality, cardiac allograft vasculopathy or primary graft failure in patients receiving heart transplants, US researchers report. [More]
Jefferson researchers discover alternate pathway that helps heart keep pumping

Jefferson researchers discover alternate pathway that helps heart keep pumping

About 5.7 million Americans have heart failure, half of whom will die from the disease within 5 years, according to the Centers for Disease Control and Prevention. [More]
Study highlights need to improve end-of-life care for all patients with serious illnesses

Study highlights need to improve end-of-life care for all patients with serious illnesses

Historically, efforts to improve end-of-life care have focused primarily on patients with cancer. But few studies have looked at the quality of end-of-life care for patients with other serious illnesses, such as lung, kidney or heart failure or dementia. [More]
Re-engineering cardiac scarring process could improve clinical outcomes for heart disease patients

Re-engineering cardiac scarring process could improve clinical outcomes for heart disease patients

Literal heartbreak, from illness or injury, triggers the body's natural healing mechanisms. [More]
Race impacts adverse outcomes in atrial fibrillation

Race impacts adverse outcomes in atrial fibrillation

Black individuals with atrial fibrillation have markedly higher rates of stroke, heart failure, coronary heart disease and mortality than their White counterparts, data from the Atherosclerosis Risk in Communities study show. [More]
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