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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.
Nanopores can be effective way to measure DNA interactions with emerging anti-cancer drugs

Nanopores can be effective way to measure DNA interactions with emerging anti-cancer drugs

Cancer thrives when mutated cells undergo frequent division. Most anti-cancer drugs work by inserting themselves in between the DNA base pairs that encode our genetic information. [More]
Hospitals with high readmission rates more likely to show better mortality scores

Hospitals with high readmission rates more likely to show better mortality scores

A group of Johns Hopkins physicians and researchers today published an article in the Journal of Hospital Medicine suggesting that data on mortality and hospital readmission used by the United States Centers for Medicare and Medicaid suggest a potentially problematic relationship. [More]
New research sheds light on underlying genetic basis of heart arrhythmias

New research sheds light on underlying genetic basis of heart arrhythmias

In the August 31 issue of Science Translational Medicine, new research from the University of Chicago shows how deficits in a specific pathway of genes can lead to the development of atrial fibrillation, a common irregular heartbeat, which poses a significant health risk. [More]
UTHealth scientists discover powerful predictors of congestive heart failure

UTHealth scientists discover powerful predictors of congestive heart failure

A team of scientists at The University of Texas Health Science Center at Houston and Baylor College of Medicine, led by Eric Boerwinkle, Ph.D., Richard Gibbs, Ph.D., and Bing Yu, Ph.D., have identified powerful predictors of congestive heart failure, a major cause of hospitalization and death in the United States. [More]
Study urges caution when using BP-lowering treatment in patients with coronary artery disease

Study urges caution when using BP-lowering treatment in patients with coronary artery disease

Caution has been urged in the use of blood pressure lowering treatment for heart disease patients after a study in more than 22 000 patients with coronary artery disease found that too low blood pressure was associated with worse outcomes. The analysis from the CLARIFY registry is presented today at ESC Congress and published in The Lancet. [More]
Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Nebivolol prevents anthracycline-induced cardiotoxicity, according to research presented at ESC Congress 2016 today by Professor Mirela Cleopatra Tomescu, a cardiologist at Victor Babes University of Medicine and Pharmacy, Timisoara, Romania. [More]
CPAP treatment offers no cardiovascular benefit in OSA patients with heart disease risk

CPAP treatment offers no cardiovascular benefit in OSA patients with heart disease risk

More than 3 years of nightly treatment with a continuous positive airway pressure (CPAP) machine did not reduce cardiovascular risk more than usual care among patients with cardiovascular disease and obstructive sleep apnea (OSA). [More]
Study shows many older jail inmates experience health-related distressing symptoms

Study shows many older jail inmates experience health-related distressing symptoms

More than 550,000 adults 55-years-old and older are arrested and detained every year--and that number is increasing rapidly. [More]
Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

For heart failure patients with cardiac implantable electronic devices (CIEDs), remote monitoring of their condition does not improve outcomes compared to usual care, according to Hot Line results presented at ESC Congress 2016 and to be simultaneously published in JAMA. [More]
Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial. [More]
Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

A therapy that uses bone-marrow stem cells to promote heart repair did not significantly improve the primary outcome over a sham procedure among patients with congestive heart failure. [More]
Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Heart failure patients have a 2% increased risk of dying with each admission to NHS hospitals, according to research presented at ESC Congress 2016 today. [More]
Alcohol-related hospitalisation linked to increased risk of ischaemic stroke in atrial fibrillation patients

Alcohol-related hospitalisation linked to increased risk of ischaemic stroke in atrial fibrillation patients

Alcohol related hospitalisation is associated with a doubled risk of ischaemic stroke risk in patients with non-valvular atrial fibrillation, according to a study presented at ESC Congress 2016 today by Dr Faris Al-Khalili, cardiologist, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden. [More]
ESC releases novel position paper on tackling cardiotoxicity of anticancer treatments

ESC releases novel position paper on tackling cardiotoxicity of anticancer treatments

The European Society of Cardiology has launched a novel position paper, under the auspices of its Committee for Practice Guidelines, on tackling the cardiac toxicity of anticancer therapies. The cardio-oncology paper is published online today in European Heart Journal and on the ESC Website. [More]
Moderate physical activity reduces risk of acute cardiovascular event in older people

Moderate physical activity reduces risk of acute cardiovascular event in older people

Moderate physical activity is associated with a greater than 50% reduction in cardiovascular death in over-65s, according to research presented at ESC Congress 2016 today. The 12 year study in nearly 2500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30%. High levels of physical activity led to greater risk reductions. [More]
Raising brain protein alleviates symptoms of Alzheimer's disease in mouse model

Raising brain protein alleviates symptoms of Alzheimer's disease in mouse model

Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer's disease in a mouse model of the disorder, according to new research published online August 25, 2016 in Scientific Reports. [More]
Surgical repair of mitral valve may provide greater benefit in patients with no symptoms

Surgical repair of mitral valve may provide greater benefit in patients with no symptoms

A new study recently published in the Journal of Thoracic and Cardiovascular Surgery questions whether patients with isolated moderate to severe mitral valve regurgitation should receive treatment in earlier stages instead of waiting until symptoms appear. [More]
New imaging technique may help detect amyloid-related heart failure

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center. [More]
MDI Biological Laboratory researchers receive patent for novel heart disease drug

MDI Biological Laboratory researchers receive patent for novel heart disease drug

The U.S. Patent and Trademark Office has announced that it will grant a patent to MDI Biological Laboratory scientists Voot P. Yin, Ph.D., and Kevin Strange, Ph.D., and their collaborator Michael Zasloff, M.D., Ph.D., for use of the small molecule MSI-1436 to stimulate the repair and regeneration of heart tissue damaged by injuries such as a heart attack. [More]
Morbidly obese individuals more likely to experience heart failure, say researchers

Morbidly obese individuals more likely to experience heart failure, say researchers

A study by Johns Hopkins researchers of more than 13,000 people has found that even after accounting for such risk factors as high blood pressure, high cholesterol and diabetes, so-called morbid obesity appears to stand alone as a standout risk for heart failure, but not for other major types of heart disease. [More]
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