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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.
Study provides key insights for effective treatment of individuals with HFpEF

Study provides key insights for effective treatment of individuals with HFpEF

The number of patients hospitalized with HFpEF is now comparable to those with traditional heart failure with a reduced ejection fraction (HFrEF) and is projected to exceed that of HFrEF within the next few years. [More]
Scientists develop prediction score to identify older adults at risk of developing pneumonia

Scientists develop prediction score to identify older adults at risk of developing pneumonia

In a study published in the Journal of American Geriatrics Society, researchers developed a "prediction score" to help healthcare professionals determine which older adults might be most at risk for developing pneumonia. [More]
Patient characteristics, outcomes differ for indoor and outdoor fallers, study shows

Patient characteristics, outcomes differ for indoor and outdoor fallers, study shows

Falling can have serious consequences for older adults, including a loss of function and increased risk of institutionalization. [More]
Sleep apnea patients with resistant hypertension may have increased risk for cardiovascular outcomes

Sleep apnea patients with resistant hypertension may have increased risk for cardiovascular outcomes

In a study of patients with hypertension, those with resistant hypertension--meaning that their blood pressure remained elevated despite concurrent use of three antihypertensive agents of different classes--had a higher rate of sleep apnea (9.6%) than those without resistant hypertension (7.2%). [More]
Clinical study examines new treatment option for aortic stenosis patients with larger valve structure

Clinical study examines new treatment option for aortic stenosis patients with larger valve structure

A clinical trial exploring a new minimally invasive treatment option for some patients with severe aortic stenosis recently launched at Baylor Jack and Jane Hamilton Heart and Vascular Hospital. [More]
Diabetic patients experience long-term survival outcomes with TAR/CABG surgery

Diabetic patients experience long-term survival outcomes with TAR/CABG surgery

Diabetic patients who undergo heart bypass surgery are living longer and have much better long-term outcomes when cardiothoracic surgeons use arteries rather than veins for the bypasses, according to a new study published online today by The Annals of Thoracic Surgery. [More]
Penn study provides more insights into cardiovascular side effects of breast cancer drug

Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. [More]
Metabolic syndrome, cardiovascular events linked to decreased sexual activity in postmenopausal women

Metabolic syndrome, cardiovascular events linked to decreased sexual activity in postmenopausal women

Understanding the effects of age and disease on sexual wellbeing is crucial as sexual health is increasingly associated with vitality. In a new study published in The American Journal of Medicine, researchers looked at the role metabolic syndrome and cardiovascular disease play in postmenopausal women's sexual health. [More]
Study finds link between AF and reduced frontal lobe brain volumes

Study finds link between AF and reduced frontal lobe brain volumes

According to a recent Framingham Heart Study, people who experience the heart arrhythmia atrial fibrillation (AF), may also suffer from a smaller brain, specifically reduced frontal lobe volume. [More]
UTHealth researchers examine effectiveness of Sapien 3 TAVR in low-risk patients with aortic stenosis

UTHealth researchers examine effectiveness of Sapien 3 TAVR in low-risk patients with aortic stenosis

The Structural Heart Program team at McGovern Medical School at The University of Texas Health Science Center at Houston is among the first in the country to investigate the safety and effectiveness of Edwards Lifesciences Sapien 3 transcatheter aortic heart valve in low surgical risk patients who suffer from severe aortic valve disease. [More]
Aerobic exercise training reestablishes cardiac protein quality control system in heart failure rats

Aerobic exercise training reestablishes cardiac protein quality control system in heart failure rats

Aerobic exercise training restored the cardiac protein quality control system in rats showed a study recently published in Journal of Cellular and Molecular Medicine. [More]
Study identifies genetic mutations responsible for development of cardiac hypertrophy in adults

Study identifies genetic mutations responsible for development of cardiac hypertrophy in adults

Investigators at Beth Israel Deaconess Medical Center have identified a developmental cause of adult-onset cardiac hypertrophy, a dangerous thickening of the heart muscle that can lead to heart failure and death. [More]
Aggressive home blood pressure monitoring may contribute to rise in emergency department visits

Aggressive home blood pressure monitoring may contribute to rise in emergency department visits

Visits to emergency departments for patients with hypertension increased by 64 percent between 2002 and 2012 while hospitalizations for those visits declined by 28 percent. [More]
New genetic test provides rapid diagnosis of mitochondrial disease

New genetic test provides rapid diagnosis of mitochondrial disease

Newcastle researchers have developed a genetic test providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene. [More]
Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Why do women have lower rates of heart failure than men for most of their lives? University of Guelph researchers have uncovered a possible clue - an actin binding protein called "CapZ" that also protects against heart attacks. [More]
Study underscores importance of targeting prevention efforts at preclinical HF stages

Study underscores importance of targeting prevention efforts at preclinical HF stages

According to a recent study of Framingham Study participants, nearly 60 percent of people have prevalent preclinical heart failure (HF) stages A and B. Heart failure occurs when the heart muscle is weakened and cannot pump enough blood to meet the body's needs for blood and oxygen. [More]
Loyola among first health systems to offer absorbable stent to heart patients

Loyola among first health systems to offer absorbable stent to heart patients

Loyola Medicine will be among the first health systems in the country to offer heart patients a new stent that is absorbed by the body once it has served its purpose. [More]
European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year. [More]
Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses. [More]
Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics, a biopharmaceutical company with the mission of developing new therapies for unmet medical needs in the field of cardiovascular diseases, today announced the initiation of its Phase IIa multicentric clinical trial of GQC101, entitled QUID HF (QUantum Genomics Incremental Dosing in Heart Failure), for the treatment of patients with chronic heart failure. The first three clinical centres of the European trial have been opened in France and Norway. [More]
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