Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

US FDA advisory panel votes yes for Edwards heart valve

An U.S. Food and Drug Administration advisory panel met Wednesday to discuss the approval of Edwards Lifesciences Corp's heart valve for patients deemed too sick to have open-heart surgery. The panel voted 9-0 with one abstention in favor of valve.

20 Jul 2011

Millennium submits VELCADE sNDA to FDA to add OS data for previously untreated multiple myeloma

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced the submission of a supplemental New Drug Application (sNDA) with the U.S. Food and Drug Administration for VELCADE® (bortezomib) for injection to add overall survival data after a five-year follow up to the product label.

20 Jul 2011

Two existing clinical stage clients expand development activities with Progenitor Cell Therapy

Progenitor Cell Therapy (PCT), an internationally recognized cell therapy services and development company, and a wholly-owned subsidiary of NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, announced today that two existing clinical stage biopharmaceutical corporate clients have chosen to expand their development activities with PCT.

18 Jul 2011

Patients with pulmonary hypertension more likely to have complications after bilateral TKA

A new study by researchers at Hospital for Special Surgery has identified patients who are at a higher risk of morbidity and mortality when undergoing knee replacement surgery in both legs at the same time.

15 Jul 2011

CLEOPATRA Phase III study on HER2-positive mBC meets primary endpoint

Genentech, a member of the Roche Group, today announced that CLEOPATRA, a pivotal Phase III study, met its primary endpoint.

15 Jul 2011

NeoStem to acquire Amorcyte

NeoStem, Inc., an international biopharmaceutical company, announced the signing of a definitive merger agreement whereby NeoStem will acquire Amorcyte, Inc., a development stage cell therapy company focusing on novel treatments for cardiovascular disease.

15 Jul 2011

Proteus receives U.S. patent for ingestible digital devices

Proteus Biomedical Inc., a pioneer in intelligent medicine, announced today that the United States Patent Office awarded U.S. Patent Number 7,978,064 to Proteus.

14 Jul 2011

Self-care, serum biomarkers improve heart failure outcomes

Doctors have been dispensing advice to heart failure patients and for the first time researchers have found that it works. While self-care is believed to improve heart failure outcomes, a highlight of the recent American Heart Association scientific statement on promoting heart failure self-care was the need to establish the mechanisms by which self-care may influence neurohormonal, inflammatory, and hemodynamic function.

14 Jul 2011

Wireless power system for ventricular assist devices holds promise

Mechanical pumps to give failing hearts a boost were originally developed as temporary measures for patients awaiting a heart transplant. But as the technology has improved, these ventricular assist devices commonly operate in patients for years, including in former vice-president Dick Cheney, whose implant this month celebrates its one-year anniversary.

13 Jul 2011

Johns Hopkins receives NHLBI grant to establish two programs in glycosciences

The National Heart, Lung and Blood Institute, one of the National Institutes of Health, has awarded two groups at the Johns Hopkins University School of Medicine each approximately $2.3 million a year for seven years to establish two Programs of Excellence in Glycosciences.

13 Jul 2011

Cardiologists still perform artery-opening procedure despite changes in guidelines

Despite changes in standard treatment practice guidelines issued by the American College of Cardiology, American Heart Association and the European Society of Cardiology several years ago, there has been no meaningful change in the nation's practice of opening completely blocked coronary arteries with balloons and stents in the days after a heart attack, according to a new study published in the July 11, 2011, issue of Archives of Internal Medicine.

12 Jul 2011

FDA approves protocol for Medtronic's SYMPLICITY HTN-3 for treatment of hypertension

Medtronic, Inc., announced today that the U.S. Food and Drug Administration (FDA) has conditionally approved the protocol for SYMPLICITY HTN-3, the company's U.S. clinical trial of renal denervation with the Symplicity Catheter System for the treatment of resistant hypertension, an especially dangerous disease affecting hundreds of millions of people worldwide.

From Medtronic 12 Jul 2011

Nurses can help manage S. African's syndemic of TB and HIV

Jason E. Farley, PhD, MPH, CRNP knows the dangers inherent to an increasingly common and hazardous syndemic in South Africa: HIV and drug-resistant tuberculosis.

11 Jul 2011

GlaxoSmithKline's Boostrix receives FDA approval to prevent tetanus, diphtheria, and pertussis

The U.S. Food and Drug Administration today approved Boostrix vaccine to prevent tetanus, diphtheria, and pertussis (whooping cough) in people ages 65 and older.

11 Jul 2011

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

Quality Of Care And Patient Outcomes In Critical Access Rural Hospitals -- This study looks at the quality of care provided by patterns of care at "critical access hospitals," a federal designation for hospitals that serve rural populations and thus have been granted special incentives under Medicare.

8 Jul 2011

First transcatheter aortic valve implantation performed at Loyola University Hospital

Toni Meyer's heart-valve disease was so severe that she suffered shortness of breath even while sitting in a chair. But after Loyola University Hospital physicians replaced her diseased aortic valve in a catheter procedure as part of a clinical trial, Meyer said she is feeling "100 percent better."

From Medtronic 7 Jul 2011

Loyola to launch interdisciplinary Geriatric Fracture Program

Loyola University Hospital is launching an interdisciplinary Geriatric Fracture Program to reduce hospital stays and complications from broken hips and other age-related fractures.

7 Jul 2011

Critical access hospitals provide lower quality of care

In an analysis of data from more than 4,500 hospitals that serve Medicare beneficiaries, critical access hospitals had fewer clinical capabilities, worse measured processes of care and higher rates of death for patients with heart attack, congestive heart failure or pneumonia, compared to non-CAHs, according to a study in the July 6 issue of JAMA.

6 Jul 2011

Scientists discover three unexpected RNAs involved in diabetes cell-death pathway

Excess nutrients, such as fat and sugar, don't just pack on the pounds but can push some cells in the body over the brink. Unable to tolerate this "toxic" environment, these cells commit suicide.

6 Jul 2011

First bloodless heart transplant on 6-year-old boy performed at Nationwide Children's Hospital

Between injuries from severe storms that ripped across the country this spring, to the typical blood donation shortage seen each and every summer, experts say that the nation's blood supply is running low. At Nationwide Children's Hospital, doctors are helping to offset that demand by what's known as "bloodless" techniques.

5 Jul 2011

Heart Failure News and Research

Further Reading

US FDA advisory panel votes yes for Edwards heart valve

Millennium submits VELCADE sNDA to FDA to add OS data for previously untreated multiple myeloma

Two existing clinical stage clients expand development activities with Progenitor Cell Therapy

Patients with pulmonary hypertension more likely to have complications after bilateral TKA

CLEOPATRA Phase III study on HER2-positive mBC meets primary endpoint

NeoStem to acquire Amorcyte

Proteus receives U.S. patent for ingestible digital devices

Self-care, serum biomarkers improve heart failure outcomes

Wireless power system for ventricular assist devices holds promise

Johns Hopkins receives NHLBI grant to establish two programs in glycosciences

Cardiologists still perform artery-opening procedure despite changes in guidelines

FDA approves protocol for Medtronic's SYMPLICITY HTN-3 for treatment of hypertension

Nurses can help manage S. African's syndemic of TB and HIV

GlaxoSmithKline's Boostrix receives FDA approval to prevent tetanus, diphtheria, and pertussis

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

First transcatheter aortic valve implantation performed at Loyola University Hospital

Loyola to launch interdisciplinary Geriatric Fracture Program

Critical access hospitals provide lower quality of care

Scientists discover three unexpected RNAs involved in diabetes cell-death pathway

First bloodless heart transplant on 6-year-old boy performed at Nationwide Children's Hospital

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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