Hemochromatosis News and Research

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Hemochromatosis is the most common form of iron overload disease. Primary hemochromatosis, also called hereditary hemochromatosis, is an inherited disease. Secondary hemochromatosis is caused by anemia, alcoholism, and other disorders.

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Genomic screening to identify hemochromatosis-;a disorder that causes iron levels in the body to rise to dangerous levels-;encourages people with the condition to seek treatment and ongoing management, a Geisinger study found.

26 Oct 2023

Gene mutation responsible for hereditary hemochromatosis may be a risk factor for movement disorders

A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes.

1 Aug 2022

Molecular autopsy of dried blood spots can identify underlying cause of sudden cardiac death in a young person

The underlying cause of sudden cardiac death (SCD) in a young person is often difficult to identify. A genetic analysis could provide more information in many cases, but blood samples are not collected routinely at the time of death, and DNA extracted from the tissues collected at autopsy is damaged because of the way they are fixed in formalin and paraffin-embedded.

30 Aug 2021

UCLA professor honored for contributions to the field of hematology

Dr. Elizabeta Nemeth, professor of medicine and director of the Center for Iron Disorders at the David Geffen School of Medicine at UCLA, has been awarded the 2021 William Dameshek Prize by the American Society of Hematology (ASH) for her contributions to the field of hematology.

2 Jul 2021

Genetic variation that regulates iron metabolism may enhance endurance performance in athletes

A genetic variation that regulates iron metabolism may enhance athletes' endurance performance, researchers at the University of Toronto have shown.

24 Mar 2021

Novel nanoscale bio-probe could detect iron disorders

Chronic iron imbalances - having either too little or too much iron in the blood - can result in medical conditions ranging from anemia and hemochromatosis through to more severe diseases, such as cancer, Parkinson's Disease and Alzheimer's Disease.

29 Apr 2020

Iron overload, variant gene and malaria resistance linked in African study

A new study shows that a rare genetic mutation giving rise to a variant of the TP53 gene called P47S causes several linked biological processes.

24 Jan 2020

AMP announces recipients of 2019's Award for Excellence in Molecular Diagnostics

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostics professional society, today announced the recipients of this year's Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious Service Award.

19 Sep 2019

Study shows hereditary hemochromatosis behind many cancers and joint diseases

A British study has found that “stealth disease”, also known as hemochromatosis, could be the reason behind several disease conditions including cancers and joint diseases.

20 Jan 2019

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

Congress’ cold shoulder sends shivers through community health centers

One community health center in New York has frozen hiring. Another in Missouri can't get a bank loan to expand.

30 Sep 2017

Inconsiderate supplementation of iron may impair ability to fight against Salmonella

One would think that too much iron is too much iron - whether it is ingested from particular foods or stored in the body genetically - and that pathogens such as Salmonella would grow identically in either case.

27 Jun 2017

Kyoto University researchers identify specific gene as key regulator in iron uptake

Maintaining a good balance of iron in the body is necessary for health: too little can lead to anemia, but too much can cause debilitating disorders such as hemochromatosis.

30 May 2017

Opportunities and risks of direct-to-consumer genetic health risk tests

Accurate genetic testing stands to transform modern medicine by offering effective, personalized treatment.

13 Apr 2017

FDA authorizes marketing of first direct-to-consumer GHR tests for certain diseases

The U.S. Food and Drug Administration today allowed marketing of 23andMe Personal Genome Service Genetic Health Risk (GHR) tests for 10 diseases or conditions.

6 Apr 2017

Researchers identify key hormone critical for preventing spread of bacterial pneumonia

Researchers have found that a hormone responsible for controlling iron metabolism helps fight off a severe form of bacterial pneumonia, and that discovery may offer a simple way to help vulnerable patients.

29 Mar 2017

Mildly elevated body iron contributes to prevalence and incidence of type 2 diabetes

Even mildly elevated body iron contributes to the prevalence and incidence of type 2 diabetes, according to research from the University of Eastern Finland.

30 Nov 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

Invitae announces dramatic expansion of genetic testing menu

Invitae Corporation (NYSE: NVTA), a genetic information company, has announced that it has more than doubled the size of its genetic testing platform to include more than 600 genes and will begin releasing the new content between now and the end of the year. Invitae is immediately expanding its menu with dozens of new test panels for hereditary cancer, cardiovascular, neuromuscular, pediatric and other rare disorders.

7 Oct 2015

CLDF collaborates with Walgreens to offer free rapid HCV testing

The Chronic Liver Disease Foundation announced today that it's collaborating with Walgreens to offer free hepatitis C (HCV) testing with the OraQuick HCV Rapid Test at more than 60 Walgreens retail pharmacies in 12 major cities throughout the country.

19 May 2015