Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Research leads to better understanding of neurodegenerative, neurodevelopmental diseases

Throughout our lives, our brains adapt to what we learn and memorise. The brain is indeed made up of complex networks of neurons and synapses that are constantly re-configured.

18 Jul 2014

Drug paraphernalia triggers reward areas of brain differently in marijuana users

New research from The University of Texas at Dallas demonstrates that drug paraphernalia triggers the reward areas of the brain differently in dependent and non-dependent marijuana users.

16 Jul 2014

Study reveals way to alleviate memory deficits for Alzheimer's disease patients

A new study from the Gladstone Institutes has revealed a way to alleviate the learning and memory deficits caused by apoE4, the most important genetic risk factor for Alzheimer's disease, improving cognition to normal levels in aged mice.

16 Jul 2014

Marginal division of striatum plays similar function in learning and memory to hippocampus

In addition to the hippocampus, the marginal division of the striatum is also involved in learning and memory.

15 Jul 2014

New data on possible protective behaviors and dementia risk factors emerges at AAIC- 2014

Participation in activities that promote mental activity, and moderate physical activity in middle age, may help protect against the development of Alzheimer's disease and dementia in later life, according to new research reported today at the Alzheimer's Association International Conference- 2014 (AAIC- 2014) in Copenhagen.

15 Jul 2014

ADSC transplantation promotes adult neurogenesis in brains of Alzheimer's disease mice

Recent evidence has demonstrated that transplantation of mesenchymal stem cells can stimulate neurogenesis in the brain of adult rat or mouse models of Alzheimer's disease (AD) and improve tissue and function injury under the condition of cerebral ischemia.

14 Jul 2014

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

A decreased ability to identify odors might indicate the development of cognitive impairment and Alzheimer's disease, while examinations of the eye could indicate the build-up of beta-amyloid, a protein associated with Alzheimer's, in the brain, according to the results of four research trials reported today at the Alzheimer's Association International Conference- 2014 (AAIC- 2014) in Copenhagen.

14 Jul 2014

Study reveals effect of 3-n-butylphthalide on chronic ischemic stroke

The pathogenesis of vascular dementia induced by chronic cerebral ischemia is complex, mainly consisting of energy metabolism disorder, oxidative stress injury, neuronal apoptotic cell death and cholinergic nerve dysfunction.

10 Jul 2014

Thyroid hormone protects cholinergic neurons in hippocampus of naturally aged mice

Can thyroid hormone protect neuronal function and increase the survival rate of naturally aged animals? Prof. Ailing Fu and her team, School of Pharmaceutical Sciences, Southwest University, China performed an animal experiment in which aged mice were administered with low dose of levothyroxine for 3 consecutive months.

9 Jul 2014

UCLA project receives $15M to restore lost memory functions in brain-injured people

The UCLA Program in Memory Restoration has been awarded up to $15 million by the Defense Advanced Research Projects Agency (DARPA) for a four -year project aiming to help brain-injured people restore lost memory functions.

9 Jul 2014

Study shows how psychedelic drug alters brain activity to produce unusual psychological effects

New research shows that our brain displays a similar pattern of activity during dreams as it does during a mind-expanding drug trip.

4 Jul 2014

New research examines brain effects of the psychedelic chemical in magic mushrooms

New research shows that our brain displays a similar pattern of activity during dreams as it does during a mind-expanding drug trip.

3 Jul 2014

New Tel Aviv University study finds link between Alzheimer's and brain hyperactivity

Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and why this elevated activity takes place hasn't yet been explained - until now.

1 Jul 2014

Early life stress can have lasting negative impacts on the brain

For children, stress can go a long way. A little bit provides a platform for learning, adapting and coping. But a lot of it - chronic, toxic stress like poverty, neglect and physical abuse - can have lasting negative impacts.

28 Jun 2014

GW clinical trial aims to identify novel modalities to reduce seizures in MTLE patients

A first-of-its-kind clinical trial at the George Washington University Medical Faculty Associates employs low-frequency deep brain stimulation to potentially help reduce epileptic seizures in patients with mesial temporal lobe epilepsy (MTLE) - the most common type of focal epilepsy that often necessitates surgical resection of the temporal lobe, risking memory function.

26 Jun 2014

Schizophrenia focus narrowed to dentate gyrus

The dentate gyrus is a likely site of pathology underlying schizophrenia, shows a study published in Molecular Psychiatry.

19 Jun 2014

Self-repairing mechanism of adult brain can help preserve brain function in Alzheimer's

New research, led by scientists at the University of Southampton, has found that neurogenesis, the self-repairing mechanism of the adult brain, can help to preserve brain function in neurodegenerative diseases such as Alzheimer's, Prion or Parkinson's.

19 Jun 2014

Stress may accelerate cognitive decline later in life

A new study published in the June 18 issue of The Journal of Neuroscience adds to a body of evidence suggesting stress may accelerate cognitive decline later in life.

18 Jun 2014

National Institutes of Health awards $3.4M grant for Alzheimer's disease research

As part of its ongoing research to better understand the complexities of the human brain, the Allen Institute for Brain Science is embarking on the first effort to map connectivity patterns across the whole brain in mouse models of Alzheimer's disease, through its recent award of a $3.4 million grant over five years from the National Institute on Aging of the National Institutes of Health.

9 Jun 2014

Research investigates effect of mindfulness training on college football players

The University of Miami Hurricanes football program will partner with UM neuroscientist Dr. Amishi Jha for an innovative research study to investigate how mindfulness training can help football players better cope with the high stakes and high demands of collegiate athletics.

5 Jun 2014