Histamine News and Research

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Histamine is a biogenic amine chemical involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

Flavonoids with potential to fight allergies and inflammation

In a recent study published in the Biomedicine & Pharmacotherapy journal, researchers explored the anti-allergic and anti-inflammatory properties of flavonoids.

28 Nov 2022

Study sheds new light on the role of IgA in food allergies

Food-specific immunoglobulin A present in the human gut does not provide protection against food allergies.

27 Nov 2022

Infancy acid suppression and antibiotic use are associated with celiac disease

Researchers determine whether exposure to certain prescriptions after the first six months of life was associated with a diagnosis of celiac disease.

20 Oct 2022

Exposure to blue light may accelerate aging

A new study provides insights into the novel mechanisms through which blue light exposure interferes with non-retinal cell metabolic pathways in flies.

5 Sep 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

Gut bacterial 'super-producer' of histamine can cause pain flare-ups in some IBS patients

Researchers from McMaster University and Queen's University have discovered a gut bacterial 'super-producer' of histamine that can cause pain flare-ups in some patients with irritable bowel syndrome (IBS).

27 Jul 2022

What causes insomnia and how to treat it?

A new study evaluates the symptoms of insomnia and its treatment as reported by patients in primary care settings.

5 Jul 2022

How do mosquito bites affect immunity?

A new study looks at the immunomodulatory effects of mosquito bites, using Aedes aegypti as the model species and humans as the host.

28 Apr 2022

New test greatly simplifies the diagnosis of allergies

Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear.

21 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

Antihistamines may offer hope for long COVID patients

Researchers offer hope that an inexpensive over-the-counter medication could improve long COVID symptoms for a large proportion of these patients.

14 Feb 2022

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Researchers in the United Kingdom have conducted an observational cohort study on hospitalized patients and have found that the degree of severity of acute coronavirus disease 2019 (COVID-19) predicts the occurrence of chronic cerebrovascular impairment. The study further suggests that the levels of cerebrovascular impairment are associated with worse cognitive, mental, and physical well-being.

7 Feb 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Treatment with antihistamines associated with improved responses to immunotherapy

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

24 Nov 2021

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

An intriguing new study reports a year-long study in patients with cMCADs from all over France.

7 Sep 2021

Over-the-counter acid reflux drug appears to improve the odds of survival for COVID-19 patients

In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. Many of the elderly patients who survived the virus were poor: not exactly the demographic you would expect to fare well in a health crisis.

20 Aug 2021

Research shines light on histamine as a potential key player in depression

Bodily inflammation dampens levels of a ‘feel-good molecule’ and antidepressants’ ability to boost them, according to new research in mice.

17 Aug 2021

Researchers identify specific cells and proteins that control the sneeze reflex

A tickle in the nose can help trigger a sneeze, expelling irritants and disease-causing pathogens. But the cellular pathways that control the sneeze reflex go far beyond the sinuses and have been poorly understood.

16 Jun 2021

Potent antibody responses to BNT162b2 COVID-19 vaccine among Japanese healthcare workers

In a paper recently uploaded to the preprint server medRxiv* by Nakajima et al. (June 4th, 2021), the antibody responses of over 2,000 Japanese healthcare workers were tracked over a period of several months, with particular regard to serum Immunoglobulin G (IgG) against the SARS-CoV-2 spike protein.

8 Jun 2021

Antihistamines might be effective in long-COVID

A team of scientists from the United Kingdom has recently revealed the therapeutic benefits of histamine receptor antagonists in reducing long-term symptoms of coronavirus disease 2019 (COVID-19). They have also indicated that T cell immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection vary between asymptomatic COVID-19 and long-COVID.

8 Jun 2021