Huntington's Disease News and Research

RSS
Huntington's disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. HD is a familial disease, passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene. If a child does not inherit the HD gene, he or she will not develop the disease and cannot pass it to subsequent generations. A person who inherits the HD gene will sooner or later develop the disease. Whether one child inherits the gene has no bearing on whether others will or will not inherit the gene. Some early symptoms of HD are mood swings, depression, irritability or trouble driving, learning new things, remembering a fact, or making a decision. As the disease progresses, concentration on intellectual tasks becomes increasingly difficult and the patient may have difficulty feeding himself or herself and swallowing. The rate of disease progression and the age of onset vary from person to person. A genetic test, coupled with a complete medical history and neurological and laboratory tests, helps physicians diagnose HD. Presymptomic testing is available for individuals who are at risk for carrying the HD gene. In 1 to 3 percent of individuals with HD, no family history of HD can be found.
Discovery of early biomarkers paves way for new insight into Huntington's disease

Discovery of early biomarkers paves way for new insight into Huntington's disease

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

Duke Health researchers identify potential new drug target for Huntington's disease

Duke Health researchers identify potential new drug target for Huntington's disease

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Designer compound may be effective tool for tackling tau-related disorders

Designer compound may be effective tool for tackling tau-related disorders

Both accelerator and brake in the brain control all types of movements, research shows

Both accelerator and brake in the brain control all types of movements, research shows

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Survey reports symptoms and treatments that impact lives of HD patients and caregivers

Survey reports symptoms and treatments that impact lives of HD patients and caregivers

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

UNC Catalyst aims to provide knowledge and research tools to tackle rare diseases

UNC Catalyst aims to provide knowledge and research tools to tackle rare diseases

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

New tool explains how proteins assemble into different liquid and gel-like solid states

New tool explains how proteins assemble into different liquid and gel-like solid states

New findings about key cellular protein could lead to treatments for neurodegenerative diseases

New findings about key cellular protein could lead to treatments for neurodegenerative diseases

Scientists discover link between Huntington's disease and dysfunction of subthalamic nucleus

Scientists discover link between Huntington's disease and dysfunction of subthalamic nucleus

New study reveals IRBIT's role in facilitating apoptosis

New study reveals IRBIT's role in facilitating apoptosis

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Tufts scientists discover reason for incidence of genetic error that causes many disorders

HD is myopathy as well as neurodegenerative disease, study suggests

HD is myopathy as well as neurodegenerative disease, study suggests

TMDU researchers identify novel type of cell death in Huntington's disease

TMDU researchers identify novel type of cell death in Huntington's disease

Rice University scientists uncover new clues to cause of Huntington's disease

Rice University scientists uncover new clues to cause of Huntington's disease

Research reveals new molecular mechanisms of Huntington's disease

Research reveals new molecular mechanisms of Huntington's disease