Hydrocortisone News and Research

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Vitamin C-B1-steroid combo associated with lower mortality in children with septic shock

Treating septic shock in children with a combination of intravenous vitamin C, vitamin B1 and hydrocortisone (a commonly used steroid) is associated with lower mortality, according to a study from Ann & Robert H. Lurie Children's Hospital of Chicago.

21 Jan 2020

Vitamin C and thiamine plus steroids do not improve septic shock outcome finds study

A randomized clinical trial showed that combining Vitamin C and thiamine with standard steroid hydrocortisone did not improve the time of survival for patients with septic shock. The study titled, “Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial,” was published in the most recent issue of JAMA.

19 Jan 2020

Study quashes the idea of using vitamin C-based cocktail for treatment of sepsis

In 2017 a paper was published asserting that intravenous vitamin C given to patients with sepsis was literally a life saver. Despite the study only looking at 47 subjects the results garnered international coverage and was adopted in many ICUs worldwide.

17 Jan 2020

Study sets the record straight on unproven therapy to treat sepsis

The Jan. 17 issue of the Journal of the American Medical Association features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert.

17 Jan 2020

Oral steroid use in patients with inflammatory diseases increases risk of infection

Oral steroid use in patients with the inflammatory diseases polymyalgia rheumatica and/or giant cell arteritis significantly increased the risk of infection, and the risk increased with higher doses, found a study in CMAJ.

24 Jun 2019

Adolescents who use cognitive reappraisal had better metabolic measures, shows study

Most teens get stressed out by their families from time to time, but whether they bottle those emotions up or put a positive spin on things may affect certain processes in the body, including blood pressure and how immune cells respond to bacterial invaders, according to Penn State researchers.

14 Dec 2018

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Takeda Pharmaceutical Company Limited today announced results from the phase 3 VISIBLE 1 clinical trial evaluating the efficacy and safety of an investigational subcutaneous formulation of the gut-selective biologic vedolizumab for maintenance therapy in adult patients with moderately to severely active ulcerative colitis who achieved clinical response* at week 6 following two doses of open-label vedolizumab intravenous induction therapy.

22 Oct 2018

Shared decision making needed to diagnose, treat, and manage patients with CAH

The Endocrine Society today issued a Clinical Practice Guideline that offers best practices for healthcare providers on how to promptly diagnose, treat, and manage patients with congenital adrenal hyperplasia, an inherited endocrine disorder, throughout their entire lives.

28 Sep 2018

Poison ivy and poison oak can cause mild to severe allergic reactions

April showers might bring May flowers, but they also bring the arrival of troublesome plants such as poison ivy and poison oak that can cause mild to severe allergic reactions.

9 May 2018

Researchers discover how a light touch can lead to unbearable itching

For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can lead to unbearable itching.

4 May 2018

Hormone imbalance may be reason for higher diabetes rates among men with insufficient sleep

Studies have found an association between insufficient sleep and the development of insulin resistance, one of the factors that cause type 2 diabetes, and now researchers have discovered a biological reason for this relationship, at least in men: an imbalance between their testosterone and cortisol hormones.

19 Mar 2018

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

Sepsis presents a major challenge for health care providers, especially in low-income countries where the mortality rate can exceed 60 percent.

27 Jun 2017

Research shows corticotrophs in the brain can influence avoidance behavior after onset of stress

German Resilience Center presents new findings on the resistance to stress. A person exposed to stress can usually rapidly adapt the own behavior to the specific situation.

14 Nov 2016

Wayne State receives NIH grant to study use of opioid addiction drug to fight relapse in recovering addicts

A team led by Wayne State University School of Medicine researcher Mark Greenwald, Ph.D., will use a four-year, $2,279,723 competitively renewed grant from the National Institute on Drug Abuse of the National Institutes of Health to explore whether the opioid addiction treatment medication buprenorphine can decrease the magnitude and/or duration of responses to stressors faced by recovering addicts.

15 Oct 2016

Endocrine Society issues new guidelines on hypopituitarism

The Endocrine Society today issued a Clinical Practice Guideline that recommends treating insufficient hormone levels in individuals with hypopituitarism by replacing hormones at levels as close to the body's natural patterns as possible.

13 Oct 2016

Dr Anjali Mahto explains how to prevent risk of mosquito bites

Nobody likes being bitten by mosquitos whether it’s at home or abroad. Consultant Dermatologist & British Skin Foundation spokesperson, Dr Anjali Mahto explains how to deter the summer pests, what to do when bitten and why they are attracted to us in the first place.

2 Jun 2016

Simple tips to reduce pain from sunburn

The British Skin Foundation has sun safety tips available to the public on this page and our primary advice is to follow these to avoid sunburn in the first place. However, we realise that sometimes accidents can happen.

19 May 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

Simple physics may play key role in helping the body to fight infection

Simple physics may play a larger role than previously thought in helping control key bodily processes - such as how the body fights infection.

11 Feb 2016

Hapten Sciences plans to initiate Phase 1 clinical trial for new poison ivy vaccine

Hapten Sciences, Inc., a privately held biotechnology company, announced today that it has filed an Investigational New Drug (IND) application and is now planning to initiate dosing of healthy volunteers in a first-in-human Phase 1 clinical trial of its lead product candidate, PDC-APB, a novel, first-in-class, compound in development for a new indication to prevent contact dermatitis due to exposure to poison ivy, oak, and sumac.

19 Nov 2015