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CUMC researchers identify mechanism of kidney transplant tolerance

CUMC researchers identify mechanism of kidney transplant tolerance

Columbia University Medical Center researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or eliminating the need for costly and potentially toxic immunosuppressant drugs and improving long-term transplant success. [More]
Egalet announces net revenues of $1.9 million for 2014

Egalet announces net revenues of $1.9 million for 2014

Egalet Corporation today reported financial results for the year ended December 31, 2014. [More]
Combined use of enalapril and folic acid can significantly reduce risk of first stroke

Combined use of enalapril and folic acid can significantly reduce risk of first stroke

In a study that included more than 20,000 adults in China with high blood pressure but without a history of stroke or heart attack, the combined use of the hypertension medication enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke, according to a study appearing in JAMA. The study is being released to coincide with its presentation at the American College of Cardiology Annual Scientific Session. [More]
Physicians develop new quality measures for treatment of childhood obstructive sleep apnea

Physicians develop new quality measures for treatment of childhood obstructive sleep apnea

A work group of physicians from leading academic medical centers across the country, including NYU Langone Medical Center, has developed new quality measures for the detection and treatment of childhood obstructive sleep apnea (OSA), a potentially morbid, life-altering condition that affects hundreds of thousands of children and adolescents nationwide. [More]
AASM publishes new quality measures for common sleep disorders

AASM publishes new quality measures for common sleep disorders

Today the American Academy of Sleep Medicine published new quality measures for five common sleep disorders, which represents a landmark achievement in the promotion of high quality, patient-centered care in the medical subspecialty of sleep medicine. [More]
Mechanistic subtypes of IPAH revealed

Mechanistic subtypes of IPAH revealed

Researchers have provided evidence for distinct processes underlying vasodilator-responsive and nonresponsive idiopathic pulmonary arterial hypertension. [More]
Combining CT measurements assists pulmonary hypertension prediction

Combining CT measurements assists pulmonary hypertension prediction

Research suggests that combining pulmonary artery and ventricular measurements improves the chances of identifying pulmonary hypertension in patients undergoing computed tomography pulmonary angiography. [More]
Metabolic derangement may facilitate cell proliferation in PAH

Metabolic derangement may facilitate cell proliferation in PAH

An enzyme that facilitates modification of proteins via a glucose metabolism pathway may promote cell proliferation in the lung tissue of patients with idiopathic pulmonary arterial hypertension, say researchers. [More]

Prognostic potential for pericardial effusion in PAH patients

Monitoring pericardial effusion on serial transthoracic echocardiograms provides useful prognostic information in patients with pulmonary arterial hypertension, research suggests. [More]
No adulthood metabolic consequences of central precocious puberty

No adulthood metabolic consequences of central precocious puberty

Researchers have found that girls with central precocious puberty have similar metabolic and general health to other women when they reach young to middle adulthood. [More]
Guanabenz drug prevents myelin loss, alleviates symptoms of MS in animal models

Guanabenz drug prevents myelin loss, alleviates symptoms of MS in animal models

An FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study. [More]
Low birth weight and hypertension during pregnancy are risk factors for severity of DDE

Low birth weight and hypertension during pregnancy are risk factors for severity of DDE

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Bertha A. Chavez Gonzalez, Universidade de Minas Gerias, Lima, San Borja, Peru, will present a study titled "Birth Weight and Pregnancy Complications Associated With the Enamel Defects." [More]
TRMC expands use of capnography to monitor patients during moderate sedation

TRMC expands use of capnography to monitor patients during moderate sedation

Tillamook Regional Medical Center recently strengthened patient safety measures by expanding its use of capnography to monitor patients during moderate sedation. Sedation is commonly used during procedures such as colonoscopies and in some instances can suppress breathing. [More]
Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Ablative Solutions, Inc., a venture-backed, privately-held clinical stage company headquartered in Kalamazoo, MI, with offices in Menlo Park, CA, announced today that it was the recipient of a "Top Cardiovascular Innovation Award" from Cardiovascular Research Technologies for the Peregrine System. [More]
Excess dietary sodium can adversely affect organs

Excess dietary sodium can adversely affect organs

You may think you're one of the lucky ones who can eat all the salty snacks and convenience foods you want and still register low numbers on the blood pressure cuff. But, new research suggests you may not be so lucky after all. [More]
Inhaled Nitric Oxide still being used in preterm neonates despite evidence of short-term benefit

Inhaled Nitric Oxide still being used in preterm neonates despite evidence of short-term benefit

Inhaled Nitric Oxide (iNO) is a drug approved by the Food and Drug Administration that is commonly used in term and near-term neonates who have severe respiratory failure caused by pulmonary hypertension. Over the last decade there have been multiple large studies trying to determine a clinical use for iNO in preterm neonates, but despite evidence of short-term benefit, this drug has not been shown to improve long-term outcomes in preemies. [More]
United Therapeutics announces FDA approval of dinutuximab for treatment of high-risk neuroblastoma

United Therapeutics announces FDA approval of dinutuximab for treatment of high-risk neuroblastoma

United Therapeutics Corporation announced today that the United States Food and Drug Administration has approved Unituxin (dinutuximab) Injection (formerly called ch14.18), in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy. [More]
Researchers study effects of pregnancy weight gain on childhood obesity risk among multi-ethnic youth

Researchers study effects of pregnancy weight gain on childhood obesity risk among multi-ethnic youth

Unhealthy weight gain in pregnancy has been linked with infant size and body composition but until now little was known about its long-term association with childhood obesity among low-income and multi-ethnic youth. [More]
Liraglutide may help obese adults achieve weight loss

Liraglutide may help obese adults achieve weight loss

Obesity guidelines recommend an initial weight loss goal of 5 to 10% of start weight to improve health. A recent study found that patients who received liraglutide 3.0 mg, combined with fewer calories and more physical activity, were more than twice as likely to achieve at least that level of weight loss, compared to patients on placebo who made similar lifestyle changes. [More]
AAPMD announces "The Silent Airway Problem: Connecting the Dots" conference

AAPMD announces "The Silent Airway Problem: Connecting the Dots" conference

The American Academy of Physiological Medicine and Dentistry (AAPMD) is leading the charge for an interdisciplinary medical approach to the diagnosis and treatment of sleep and breathing disorders, which research indicates contribute to a range of serious physiological, cognitive, behavioral and performance conditions in children and adults. [More]
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