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Celgene receives FDA approval for POMALYST to treat multiple myeloma

Celgene receives FDA approval for POMALYST to treat multiple myeloma

Celgene Corporation today announced the U.S. Food and Drug Administration (FDA) has approved POMALYST brand therapy (pomalidomide) for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy. [More]
Glimmer of hope for imatinib-resistant GIST

Glimmer of hope for imatinib-resistant GIST

The monoclonal antibody SR1 can significantly inhibit gastrointestinal stromal tumor cell growth, report researchers in the Proceedings of the National Academy of Sciences. [More]
Acute schizophrenia shows increased NMDA-R antibody prevalence

Acute schizophrenia shows increased NMDA-R antibody prevalence

Patients with acute schizophrenia have an increased prevalence of N-methyl-D-aspartate glutamate receptor antibodies that is distinct from that seen in NMDA-R encephalitis, scientists have found. [More]
Children with eczema have distinct gut microbiome

Children with eczema have distinct gut microbiome

Infants with eczema have more diverse total gut microbiota than those without the skin condition, show study findings. [More]
Early hepatitis B vaccination may be ineffective in teenagers

Early hepatitis B vaccination may be ineffective in teenagers

Research reveals that many infants who receive the complete series of hepatitis B virus vaccinations have lost their protection by the time they reach adolescence. [More]

High vitamin D in pregnancy may increase food allergy risk in children

Study results published in Allergy suggest that supplementing pregnant women with vitamin D may increase their children’s risk for developing food allergy in infancy. [More]

Brake for skin inflammation discovered

The absence of a protein called Ctip2 in the skin allows increased levels of T-helper 2 cytokines and may have a role in conditions such as atopic dermatitis, research in mice suggests. [More]

T. gondii infection linked to bipolar disorder risk

Results from a French study support an association between Toxoplasma gondii infection and bipolar disorder. [More]

Immune response more complicated than thought

Researchers have found that the orientation and concentration of antibodies could determine the control of bacterial infection. [More]
Cause of recurrent infections in MECP2 duplication syndrome identified

Cause of recurrent infections in MECP2 duplication syndrome identified

US study results show that the genetic abnormality underlying the pediatric condition methyl-CpG binding protein 2 duplication syndrome also causes immune dysfunction. [More]

Antibody type prognostic for myasthenia gravis patients

Patients who have myasthenia gravis are more likely to have a severe form of the disease and more difficulty achieving remission if they are seropositive for antibodies to muscle-specific kinase, report researchers. [More]
Genetic innovations for pneumonia diagnosis in children

Genetic innovations for pneumonia diagnosis in children

Polymerase chain reaction could help diagnose Mycoplasmia pneumonia infection in children, researchers say. [More]
House passes bio-threat vaccines, Medicare coverage bills

House passes bio-threat vaccines, Medicare coverage bills

The House passed several health measures Wednesday including bills on developing vaccines to thwart bio-threats and on Medicare coverage for immune deficiency care. [More]
Biotest receives FDA approval for BIVIGAM to treat primary humoral immunodeficiency

Biotest receives FDA approval for BIVIGAM to treat primary humoral immunodeficiency

Biotest AG announced today that Biotest Pharmaceuticals Corporation received approval for BIVIGAM for the treatment of patients with Primary Humoral Immunodeficiency (PI) from the U.S. Food and Drug Administration (FDA). [More]
AHA/ASA identify top cardiovascular and stroke research advances for 2012

AHA/ASA identify top cardiovascular and stroke research advances for 2012

Resuscitation, cell regeneration, a new high blood pressure treatment and developments in devices for treating stroke are among the key scientific findings that make up this year's top cardiovascular and stroke research identified by the American Heart Association and American Stroke Association. [More]
NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections

NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the publication of data from its first-in-human Phase 1 study of its NDV-3 vaccine program in the journal Vaccine. [More]

High-altitude treatment may help severe asthma patients

Individuals with severe refractory asthma may benefit from high-altitude treatment, irrespective of their sensitivity to airborne allergens, suggest findings from a study conducted in the Swiss Alps. [More]
Inflammatory marker targeted in ear infection

Inflammatory marker targeted in ear infection

Systemic injection of an antibody against granulocyte/macrophage colony-stimulating factor inhibits middle-ear inflammation induced by lipopolysaccharide in mice, study findings show. [More]

University of Liverpool to conduct immunoglobulin clinical study for complex regional pain syndrome

Scientists at the University of Liverpool are leading a -1.5 million project to study `immunoglobulin', a type of drug which has been shown to ease complex regional pain syndrome (CRPS). [More]

Triclosan exposure linked to allergies in children

Norwegian children with high levels of urinary triclosan are more likely to have allergies than children with lower levels, report researchers in Allergy. [More]