Immunophenotyping News and Research

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Immunophenotyping is a test used to identify cells on the basis of the types of markers or antigens present on the cell’s surface, nucleus, or cytoplasm. This technique helps identify the lineage of cells using antibodies that detect markers or antigens on the cells, hence the “immuno-” prefix.

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

A study examining 1031 hospitalized COVID-19 patients found that aging significantly impacts immune responses, viral dynamics, and the nasal microbiome, with older adults experiencing more severe disease symptoms and delayed viral clearance.

18 Apr 2024

Machine learning models identify immunophenotypes in NSCLC for immunotherapy guidance

A new study examines the development of two machine learning models to classify the immunophenotype of a cancer specimen.

16 Apr 2024

Long COVID's biological blueprint: new study offers promising insights

Researchers designed a cross-sectional study to investigate the biological underpinnings of “Long COVID”, the post-acute infection syndrome triggered by SARS-CoV-2.

27 Sep 2023

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate."

24 May 2023

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Research investigates whether the severity of SARS-CoV-2 infection can be predicted by analyzing the immunophenotype in the blood of cardiovascular disease (CVD) patients.

1 May 2023

The critical role of flow cytometry in CAR+ T-Cell trials

In this interview, Ryan Muise talks to AZoNetwork about the added value of using flow cytometry in CAR T-Cell clinical trials.

From Cerba Research 6 Dec 2022

PerkinElmer unveils industry-first cell analysis solution to streamline cell and gene therapy research and manufacturing

PerkinElmer, Inc., (NYSE: PKI), a global leader committed to innovating for a healthier world, today launched the Cellaca® PLX Image Cytometry System, a first-of-its-kind benchtop platform that enables researchers to assess multiple Critical Quality Attributes (CQAs) of cell samples in a single automated workflow, including cell identity, quality and quantity.

From Revvity 29 Sep 2022

Mechanism of action of different COVID-19 vaccines

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Tuebingen and Imperial College London assessed humoral and cellular immune responses elicited by the recombinant adenoviral vector (rAdVV)- and messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines.

14 Sep 2022

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

Researchers reviewed the epidemiology, clinical character, treatment, and prevention of human monkeypox.

8 Sep 2022

How could SARS-CoV-2 viral infection modulate the immune landscape during the active infection phase and recovery in pregnant females?

Researchers examined immune reflexes towards SARS-CoV-2 infection among pregnant women.

24 Aug 2022

What are the unique traits of Long COVID?

In a new study, researchers identified distinctive characteristics of post-acute sequelae of COVID-19 (PASC) via immune profiling.

12 Aug 2022

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

In a recent article, longitudinal clinical phenotypes were described based on respiratory ordinal scales.

7 Jul 2022

Obesity causes COVID vaccines to lose their efficacy more rapidly

In a recent study posted to the medRxiv* pre-print server, researchers examined a clinical cohort of severely obese people vaccinated with coronavirus disease 2019 (COVID-19) vaccines to determine the relationship between an individual's body mass index (BMI) and COVID-19-related hospitalization and mortality.

16 Jun 2022

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

Researchers evaluated the impact of CMV seropositivity on humoral and cellular immune responses generated after double and/or triple mRNA vaccination against SARS-CoV-2 among the elderly.

31 May 2022

Immunophenotyping News and Research

Further Reading

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

Machine learning models identify immunophenotypes in NSCLC for immunotherapy guidance

Long COVID's biological blueprint: new study offers promising insights

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

The critical role of flow cytometry in CAR+ T-Cell trials

PerkinElmer unveils industry-first cell analysis solution to streamline cell and gene therapy research and manufacturing

Mechanism of action of different COVID-19 vaccines

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

How could SARS-CoV-2 viral infection modulate the immune landscape during the active infection phase and recovery in pregnant females?

What are the unique traits of Long COVID?

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

Obesity causes COVID vaccines to lose their efficacy more rapidly

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

Study investigates the cause of lymphopenia as seen in COVID-19 patients

Waning antibody responses in SARS-CoV-2-infected or vaccinated population

Real world evidence on acquired immunity from vaccines and SARS-CoV-2 infection

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Exploring SARS-CoV-2 vaccine responsiveness in immunosuppressed patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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