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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.
Researchers identify attractive drug candidate to target glioma tumors

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed. [More]
Common bacterium that causes gum infections may trigger rheumatoid arthritis

Common bacterium that causes gum infections may trigger rheumatoid arthritis

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory "autoimmune" response characteristic of chronic, joint-destroying rheumatoid arthritis (RA). [More]
Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center. [More]
Research shows alternative strategy to administer antibody-based immunotherapy for bladder cancer

Research shows alternative strategy to administer antibody-based immunotherapy for bladder cancer

Antibody-based immunotherapy is a new promising method to treat cancer. Unfortunately, today's treatments can result in adverse side effects. [More]
Scientists find novel way for earlier detection of deadly Merkel cell carcinoma

Scientists find novel way for earlier detection of deadly Merkel cell carcinoma

Scientists have found a way to detect earlier if a deadly cancer, Merkel cell carcinoma (MCC), is recurring in patients, according to a paper to be published 11 a.m. Eastern time, Dec. 7, in the journal Cancer. [More]
PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumour surgically removed. [More]
Experimental T-cell therapy shows promise in preventing AML relapse

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells. [More]
Dual therapy safe and effective in patients with recurrent Hodgkin lymphoma

Dual therapy safe and effective in patients with recurrent Hodgkin lymphoma

The combination of two new drugs that harness the body's immune system is safe and effective, destroying most cancer cells in 64 percent of patients with recurrent Hodgkin lymphoma, according to the results of an early-phase study. [More]
New FDA-approved drug helps patients fight against late-stage lung cancer

New FDA-approved drug helps patients fight against late-stage lung cancer

A new drug has been approved by the FDA in the fight against lung cancer. Tecentriq is being used by patients like Cornelius Bresnan, who had late-stage cancer. [More]
UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs. [More]
New device could revolutionize drug delivery to treat cancer and other diseases, study shows

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

A new study by Lyle Hood, assistant professor of mechanical engineering at The University of Texas at San Antonio, describes a new device that could revolutionize the delivery of medicine to treat cancer as well as a host of other diseases and ailments. [More]
Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

An international group of researchers report success in mice of a method of using positron emission tomography scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer. [More]
TGen and City of Hope collaborate to accelerate precision medicine research

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients. [More]
MGH researchers develop new methods for mapping and measuring solid stress in tumors

MGH researchers develop new methods for mapping and measuring solid stress in tumors

Massachusetts General Hospital investigators have developed new methods for mapping and measuring solid stress - the force exerted by solid and elastic components - within tumors, an accomplishment that may lead to improved understanding of those forces and their consequences and to novel treatment strategies. [More]
CNIC study characterizes key signal that impedes intercellular communication

CNIC study characterizes key signal that impedes intercellular communication

A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III, led by Prof. Francisco Sánchez-Madrid, has characterized a cell signal that impedes intercellular communication and could play a central role in biomedical strategies such as gene therapy, vaccine design, and immunotherapy. [More]
Clinically-proven pharmacy product effective against causes of Traveller's Diarrhoea

Clinically-proven pharmacy product effective against causes of Traveller's Diarrhoea

It is not only overseas holidays that can be ruined by the dreaded Traveller's Diarrhoea. [More]
ADVANCECAT enables development of advanced therapies to benefit Catalan health system

ADVANCECAT enables development of advanced therapies to benefit Catalan health system

Enabling the arrival of advanced therapies from pre-clinical stages to industrial production and clinical application: this is the objective of ADVANCECAT project, led by the University of Barcelona and Ferrer, and build up by eighteen entities of the health field in which there are two universities, twelve biomedical research institutes or private foundations, and four companies. [More]
Leading nonprofit patient education organization offers allergy-related restaurant safety tips

Leading nonprofit patient education organization offers allergy-related restaurant safety tips

Eating out is an American pastime - but for the millions of Americans with food or latex allergies, navigating the maze of restaurant and menu options can prove challenging, especially during the hustle and bustle of the holidays. [More]
Study shows new drug combination effective in treating precancerous skin lesions

Study shows new drug combination effective in treating precancerous skin lesions

A combination of two topical drugs that have been in use for years triggers a robust immune response against precancerous skin lesions, according to a new study. The research, from Washington University School of Medicine in St. Louis and Harvard Medical School, shows that the therapy activates the immune system's T cells, which then attack the abnormal skin cells. [More]
Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment

Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment

Immunotherapy continues to revolutionize the field of non-small cell lung cancer (NSCLC), with researchers now focusing on the optimal use of immune agents in the frontline setting. [More]
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