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Malaria parasites use complement system to evade human immune response, study finds

Malaria parasites use complement system to evade human immune response, study finds

The malaria parasite Plasmodium falciparum hijacks an immune system process to invade red blood cells, according to a study led by researchers at Penn State College of Medicine. Understanding how malaria invades the cells could lead to a more effective vaccine. [More]
World Health Assembly underscores need for multisectoral action to achieve health-related SDGs

World Health Assembly underscores need for multisectoral action to achieve health-related SDGs

Christiana Figueres, Executive Secretary of the United Nations Framework Convention on Climate Change, addressed the World Health Assembly today. [More]
ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Initiating antiretroviral therapy (ART) soon after diagnosis of an HIV infection did not prevent the progression of significant arterial inflammation in a small group of previously untreated patients. [More]
New technique to grow blood vessels could accelerate growth of regenerative medicine

New technique to grow blood vessels could accelerate growth of regenerative medicine

In addition the technique to grow the blood vessels in a 3D scaffold cuts down on the risk of transplant rejection because it uses cells from the patient. It was developed by researchers from the University of Bath's Department of Pharmacy and Pharmacology, working with colleagues at Bristol Heart Institute. [More]
First clinical trial to study use of Chinese Herbal Medicines in treating RUTIs

First clinical trial to study use of Chinese Herbal Medicines in treating RUTIs

Researchers at the University of Southampton are to study the use of Chinese Herbal Medicines in treating recurrent urinary tract infections (RUTIs), in the first clinical trial of its kind in the UK. [More]
Study highlights need of better diagnostic criteria for people suffering from debilitating grief

Study highlights need of better diagnostic criteria for people suffering from debilitating grief

To better identify and diagnose those suffering from debilitating grief after the death of a loved one, proposed diagnostic criteria need significant modifications, according to research published today in the American Journal of Psychiatry - the first study of its kind to study the performance of newly proposed criteria. [More]
Single enzyme doing the work of a trio could offer precise way to treat diseases

Single enzyme doing the work of a trio could offer precise way to treat diseases

Researchers identified a single enzyme doing the work of a trio thought necessary to control a common cellular signaling process being pursued as a therapeutic target. [More]
Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list." [More]
Researchers find genetic mutations linked to increased risk factor for PTSD

Researchers find genetic mutations linked to increased risk factor for PTSD

In the largest study of DNA samples from service members with Post-Traumatic Stress Disorder (PTSD), researchers have identified genetic mutations that may be associated with an increased risk factor for PTSD. [More]
Food-triggered atopic dermatitis in children may lead to life-threatening anaphylaxis risk

Food-triggered atopic dermatitis in children may lead to life-threatening anaphylaxis risk

Elimination of the food that triggers atopic dermatitis, or eczema, is associated with increased risk of developing immediate reactions to that food, according to the results of a large-scale study recently published in the Journal of Allergy and Clinical Immunology. [More]
Novel strategy to predict antigenic evolution of circulating influenza viruses

Novel strategy to predict antigenic evolution of circulating influenza viruses

During the 2014-15 flu season, the poor match between the virus used to make the world's vaccine stocks and the circulating seasonal virus yielded a vaccine that was less than 20 percent effective. [More]

Researchers call for creation of global early warning system for infectious diseases

In the recent issue of EMBO reports, Barbara Han of the Cary Institute of Ecosystem Studies and John Drake of the University of Georgia Odum School of Ecology call for the creation of a global early warning system for infectious diseases. [More]
New collaborative research center to investigate promising aspects of mucosal immunology

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment. [More]
Research provides pathway toward creation of first broad-spectrum antiviral drug

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state. [More]
NS5 viral protein could be promising vaccine target against Zika virus

NS5 viral protein could be promising vaccine target against Zika virus

A viral protein known as NS5 is a promising target for vaccines against Zika and related viruses, according to National Institutes of Health scientists and colleagues at Mount Sinai's Icahn School of Medicine. [More]
New drug that combines methicillin with polymer BPEI can combat MRSA

New drug that combines methicillin with polymer BPEI can combat MRSA

A University of Oklahoma team of chemists has developed a new antibiotic formulation to fight the sometimes deadly staph infection caused by methicillin-resistant S. aureus or MRSA and other antibiotic-resistant infectious bacteria. [More]
Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Acute HIV infection (AHI) contributes significantly to HIV transmission and may be important for intervention strategies seeking to reduce incidence and achieve a functional cure. [More]
Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

A new study shows that repeated radiation therapy used to target tumors in the brain may not be as safe to healthy brain cells as previously assumed. [More]
Unlocking the dark proteome: an interview with Dr Kriwacki

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations. [More]
Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

With more than 36.9 million people infected globally, HIV continues to be a major public health issue. Those living with the virus are at an increased risk for other non-AIDS diseases, such as cardiovascular disease and cancer, and though it's not entirely clear why, this has been associated with inflammation and abnormal blood clotting. [More]
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