Infectious Diseases News and Research

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Global Health Service Partnership 'could be the start of something big'

Writing in GlobalPost's "Global Pulse" blog, Claire Panosian Dunavan, a professor of medicine and infectious diseases at the University of California, Los Angeles, reflects on the Global Health Service Partnership, a new public-private partnership launched by Vanessa Kerry, daughter of Sen. John Kerry (D-Mass.) "to boost the education of doctors and nurses in sub-Saharan Africa."

25 Oct 2012

Communicable diseases responsible for majority of deaths in Africa, WHO official says

Speaking on Monday in Luanda, Angola, at the opening session of the inaugural meeting on Medical Education, sponsored by the Faculty of Medicine of Agostinho Neto University, WHO Regional Director for Africa Luis Gomes Sambo said communicable diseases account for 63 percent of deaths in Africa, with HIV and tuberculosis (TB) responsible for the majority of those, the Angola Press reports.

25 Oct 2012

BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia

BioLineRx, a biopharmaceutical development company, announced today that it intends to conduct an interim analysis of the Phase II/III CLARITY trial of BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia.

25 Oct 2012

Scientists unravel physical properties of lung mucus

Mucus coats our airways' internal surfaces. The viscous gel humidifies the lungs and prevents viruses and other small particles like diesel soot from entering the body unchecked. Previously unclear was the extent to which such nanoparticles are able to move through the lungs' mucus. Here, the research evidence was contradictory. Scientists could not explain why, in inhaled medication development, drug nanoparticles often simply got stuck in the mucus never making it to their target destination inside the lung cells.

25 Oct 2012

New method of testing for West Nile virus

While the United States has largely been spared the scourge of mosquito-borne diseases endemic to the developing world-including yellow fever, malaria and dengue fever-mosquito-related illnesses in the US are on the rise. One pathogen of increasing concern in the U.S. is an arbovirus known as West Nile.

24 Oct 2012

Flu protection: an interview with Dr Gillian SteelFisher of the Harvard School of Public Health in Boston, USA

In 2009, a new strain of influenza, or flu, virus emerged and spread rapidly to many countries around the world. It was declared a pandemic by the World Health Organization (WHO) in June 2009.

24 Oct 2012

NEJM report on best options for safe, effective patient treatment against fungal meningitis

As the number of fungal meningitis cases continues to rise, physicians across the country are faced with how best to provide the early treatment that can save lives.

24 Oct 2012

Warning against colloids in fluid resuscitation

Hydroxyethyl starch offers no benefits over saline for fluid resuscitation in critically ill patients and may have renal consequences, shows a randomized trial.

23 Oct 2012

Up to 10% of acute lung injuries may be drug-related

A population-based study has found that drug-induced acute lung injury accounts for around 9.5% of all acute lung injury cases.

23 Oct 2012

Almost all children on intensive care units given ‘off-label’ drugs

Study results show that a very high proportion of children admitted to intensive care units are treated with “off-label” drugs that have not been tested for the specific age or condition of the patient.

23 Oct 2012

Examining ethics surrounding Taliban's ban on polio vaccination in Pakistan

Writing in the Global Bioethics Blog, Stuart Rennie, a bioethics researcher and professor, notes another polio worker was killed in Pakistan last week and describes Taliban opposition to U.S.-supported polio vaccination efforts in Pakistan.

23 Oct 2012

Glioblastoma multiforme can originate from cortical neurons

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

23 Oct 2012

Sanofi presents overview of Phase II and III trials for quadrivalent influenza vaccine

Sanofi Pasteur, the vaccines division of Sanofi, presented today an overview of Phase II and Phase III clinical trials for its investigational quadrivalent influenza vaccine (QIV).

23 Oct 2012

'Fresher' blood transfusion does not mean better outcomes

Blood that has been stored for 2 weeks or more before being used in transfusions for critically ill patients does not appear to cause adverse effects, report US researchers.

22 Oct 2012

Mother–baby intensive care admission carries high mortality risk

Mothers and newborns who are both admitted to an intensive care unit are significantly more likely to die than mother–baby pairs who are not, a study suggests.

22 Oct 2012

PLoS ONE publishes review of AntiViral-HyperActivation Limiting Therapeutics clinical trial

ViroStatics, a private Italian/American biopharmaceutical company developing novel therapeutics for viral and other chronic diseases, announced that a review of the first human clinical trial to test a new class of anti-HIV medications known as AntiViral-HyperActivation Limiting Therapeutics (AV-HALTs) has been published in the peer-reviewed journal PLoS ONE.

22 Oct 2012

Researchers discover Hyalomma ticks in migratory birds

A type of haemorrhagic fever (Crimean-Congo) that is prevalent in Africa, Asia, and the Balkans has begun to spread to new areas in southern Europe. Now Swedish researchers have shown that migratory birds carrying ticks are the possible source of contagion.

22 Oct 2012

Microgravity and prolonged space flight could give unique advantages to germs

The cabin of a spacecraft halfway to Mars would be the least convenient place -- one cannot say "on earth" -- for a Salmonella or Pneumococcus outbreak, but a wide-ranging new paper suggests that microgravity and prolonged space flight could give unique advantages to germs.

22 Oct 2012

Mistakes are still commonly made in prescriptions of antiretroviral medications

Research presented at IDWeek 2012- concludes that despite advances in electronic medical records, mistakes are still commonly made in the prescription of antiretroviral medications for hospitalized HIV-positive patients. At the same time, a trio of studies suggests however, that electronic records in combination with increased clinical education can help to greatly decrease medical errors.

20 Oct 2012

MRSA-related pneumonia can be effectively treated in half the recommended time

The national practice guideline for treating MRSA-related pneumonia is seven to 21 days. A Henry Ford Hospital study found that effective treatment can be done in half the time.

20 Oct 2012