Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is an ongoing or chronic health problem that causes inflammation and swelling in the digestive tract. The irritation causes bleeding sores called ulcers to form along the digestive tract. This in turn can cause crampy, abdominal pain and severe bloody diarrhea.

What is Ulcerative Colitis?

Ulcerative colitis is a chronic condition that affects the large intestines, particularly the colon. It is classified as one of the two inflammatory bowel diseases along with Crohn’s disease.

Ulcerative Colitis Causes

Genetics of Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD) in Pregnancy

Dysbiosis and the Microbiome

Mesentery: a new organ?

FODMAP Research

Inflammatory Bowel Disease and Colorectal Cancer

Short-Chain Fatty Acids (SCFAs)

Latest Inflammatory Bowel Disease News and Research

Newly discovered cause for asthma sparks hope for treatment

Scientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-threatening disease.

4 Apr 2024

Does IBD affect cancer risk?

Research suggests no strong genetic link between inflammatory bowel disease and increased cancer risk, with specific exceptions in European populations for Crohn's disease and ulcerative colitis.

3 Apr 2024

Systemic Inflammation Index: A new hope for autoimmune disease management

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases.

2 Apr 2024

Certain gut bacteria may help lower cholesterol and heart disease risk

Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease.

2 Apr 2024

Using microbiota analysis for health and disease management

The human body harbors approximately 30 trillion microbes, known collectively as the microbiota.

28 Mar 2024

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments.

25 Mar 2024

Risk factors for serious inflammatory conditions in IBD patients identified

Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.

20 Mar 2024

Digital twins: Revolutionizing autoimmune disease treatment

Individual patients with autoimmune diseases can receive tailored medication by computationally treating their so-called digital twins with thousands of medications.

20 Mar 2024

Implantable temperature sensor detects inflammatory flareups in patients with Crohn's disease

A team of Northwestern University scientists has developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease.

18 Mar 2024

Non-invasive blood test shows 83% sensitivity in detecting colorectal cancer, offering hope for early diagnosis

The performance of a blood-based testing method that uses cell-free deoxyribonucleic acid (DNA) to screen for colorectal cancer.

18 Mar 2024

Gut bacteria-derived serotonin promotes the development of immune cells in newborns

Weill Cornell Medicine investigators discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells.

15 Mar 2024

Ultra-processed foods: The new silent killer

From fizzy drinks to cereals and packaged snacks to processed meat, ultra-processed foods are packed with additives.

14 Mar 2024

Living with IBD: What coping strategies are most effective?

The results of a systematic review that explored the impact of different coping strategies for people living with inflammatory bowel disease (IBD).

14 Mar 2024

Scientists uncover an overlooked mechanism in the gut immune system of Crohn's disease patients

A team of scientists from DTU and other European universities have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn's disease.

13 Mar 2024

Exploring the power of diet: A new frontier in disease management and cancer treatment

The therapeutic potential of and molecular mechanisms through which dietary interventions impact a wide range of human diseases.

13 Mar 2024

How does childhood exposure to agricultural land influence inflammatory bowel disease risk?

The impact of environmental exposures in early life on the risk of inflammatory bowel disease (IBD), ulcerative colitis (UC), and Crohn’s disease (CD).

13 Mar 2024

Limoncella apple polyphenol extract shines in IBD liver damage study

'Limoncella' apple polyphenol extract (LAPE) shows promise in reducing liver and intestinal inflammation in a mouse model of inflammatory bowel disease (IBD), highlighting potential natural treatment pathways

12 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers assessed the risk of depression following the diagnosis of rheumatoid arthritis (RA).

8 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024