Inflammatory Disease News and Research

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Research explores how moms' obesity reprograms babies

Research increasingly suggests that when a woman with obesity becomes pregnant, a process of "fetal reprogramming" increases the risk that her baby will face problems like obesity, Type 2 diabetes and liver disease earlier in life.

23 Apr 2024

Breakthrough study reveals role of histone deacetylases in inflammatory bowel disease

In a scientific breakthrough, Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

22 Apr 2024

Asthma attacks cause airway damage beyond inflammation, research shows

In asthma, the tightening of muscles around the bronchi causes damage to the airway by squeezing and destroying epithelial cells, which promotes the airway inflammation and mucus production often associated with an asthma attack, researchers report.

4 Apr 2024

Newly discovered cause for asthma sparks hope for treatment

Scientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-threatening disease.

4 Apr 2024

New immunotherapy strategy potentially lays the groundwork for treating autoimmune diseases

Mayo Clinic scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases.

1 Apr 2024

Rising antimicrobial resistance in STIs: A call for global action

Review delves into the rising challenge of antimicrobial resistance in sexually transmitted infections, underscoring the need for innovative treatments and the critical role of global surveillance in managing diseases like gonorrhea and syphilis.

21 Mar 2024

99mTc-maraciclatide holds potential as a non-invasive test for early-stage endometriosis

The presentation summarized the preliminary findings from patients with known or suspected endometriosis who were imaged with a SPECT-CT camera and subsequently underwent planned laparoscopic surgery, a key-hole surgical procedure to establish the presence, absence and location of endometriotic lesions.

15 Mar 2024

ECDC raises alarm over rising STI rates across Europe

The findings reveal a troubling surge in cases of syphilis, gonorrhoea, and chlamydia, indicating a pressing need for heightened awareness of STI transmission, and the need to enhance robust prevention, access to testing, and effective treatment to address this public health challenge.

7 Mar 2024

Breakthrough blood test developed for early detection of sarcoidosis

A research project led by Lobelia Samavati, M.D., professor of internal medicine and molecular medicine and genetics at the Wayne State University School of Medicine, and supported by the National Institutes of Health (NIH), has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs.

28 Feb 2024

Study links ultra-processed foods to gut health risks

A review in Nature Reviews Gastroenterology & Hepatology synthesizes evidence on the negative impacts of ultra-processed foods and food additives on gut health, linking them to chronic diseases and alterations in the gut microbiome.

25 Feb 2024

Researchers develop new tool to rapidly and inexpensively diagnose sarcoidosis

A research project supported by the National Institutes of Health has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs in the body.

22 Feb 2024

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Identifying immunotherapy resistance in liver cancer linked to steatotic disease

A research team of Canadian and French scientists, led by INRS professor Maya Saleh, has been investigating immunotherapy resistance in certain patients with hepatocellular carcinoma (HCC) associated with steatotic liver disease.

14 Feb 2024

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

13 Feb 2024

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award up to US$1.8 million to biotechnology company, Visby Medical, to develop a portable rapid polymerase chain reaction (PCR) diagnostic to detect the presence of the pathogen that causes gonorrhea, Neisseria gonorrhoeae (NG), and its susceptibility to ciprofloxacin, a former frontline oral antibiotic that can no longer treat resistant NG.

9 Feb 2024

Hormonal steroids could make gonorrhea untreatable

You know that package warning that oral birth control won't prevent STIs? Well in the case of gonorrhea, the sexually transmitted bacterium that causes the disease can use those hormones to help it resist antibiotic attacks.

8 Feb 2024

World-first discovery offers potential cure for lupus

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.

6 Feb 2024

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.

1 Feb 2024

Interventions for mood show promise for the management of IBD in improving mental health, inflammation and disease outcomes

Researchers performed a meta-analysis to explore the impact of mood interventions on inflammatory disease activity in inflammatory bowel disease (IBD).

29 Jan 2024

Study reveals new mechanisms involved in the development of inflammatory cardiovascular diseases

A team led by LMU researchers Christian Weber and Yvonne Döring has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases.

24 Jan 2024