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Influenza (the flu) is a contagious respiratory illness caused by influenza viruses. It can cause mild to severe illness, and at times can lead to death. The best way to prevent the flu is by getting a flu vaccination each year. Every year in the United States, on average 5% to 20% of the population gets the flu; more than 200,000 people are hospitalized from flu complications, and; about 36,000 people die from flu-related causes. Some people, such as older people, young children, and people with certain health conditions, are at high risk for serious flu complications.
BiondVax's patent application for universal flu vaccine accepted in Israel

BiondVax's patent application for universal flu vaccine accepted in Israel

BiondVax Pharmaceuticals Ltd. which is developing the Universal Flu Vaccine, announced today that its patent application in Israel on the Multimeric Multi-Epitope Polypeptide Influenza Vaccines (a universal flu vaccine), was accepted. [More]
Flu vaccine: the facts. An interview with Dr Lisa Maragakis

Flu vaccine: the facts. An interview with Dr Lisa Maragakis

There are different formulations of the flu vaccine but in general they all do the same thing, which is to stimulate our body's immune system to recognize and fight against the influenza virus. [More]
Luminex's NxTAG Respiratory Pathogen Panel obtains FDA clearance

Luminex's NxTAG Respiratory Pathogen Panel obtains FDA clearance

Luminex Corporation today announced that it has received FDA clearance for its NxTAG Respiratory Pathogen Panel that detects 20 clinically relevant viral and bacterial respiratory pathogens, including the atypical bacteria Chlamydophila pneumoniae and Mycoplasma pneumonia. [More]
Findings show promising evidence for creating broad-spectrum antiviral

Findings show promising evidence for creating broad-spectrum antiviral

UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses. [More]
Molecular signatures can predict flu vaccine responses in young and old

Molecular signatures can predict flu vaccine responses in young and old

What factors inhibit strong responses to seasonal flu vaccines in the elderly? Why do anti-flu antibodies last longer after vaccination in some people? Answers are emerging from an Emory University-based systems biology analysis of blood samples from more than 400 volunteers who received seasonal flu vaccines. Bali Pulendran, PhD, led a team of researchers who tracked patterns of gene expression, known as molecular signatures, of strong immune responses in volunteers' blood across five consecutive seasons from 2007 to 2011. [More]
SLU researcher discovered world's first dengue vaccine

SLU researcher discovered world's first dengue vaccine

A vaccine to prevent dengue fever discovered by a Saint Louis University researcher in 1997 and now licensed worldwide by Sanofi Pasteur has been approved for use in Mexico. Dengvaxia is the world's first vaccine approved to prevent dengue fever, which is a virus spread by mosquitoes primarily in tropical and sub-tropical areas. [More]
NIAID scientists successfully test prime-boost H7N9 influenza vaccine concept in clinical trial

NIAID scientists successfully test prime-boost H7N9 influenza vaccine concept in clinical trial

In clinical trials, several candidate H7N9 pandemic influenza vaccines made from inactivated viruses have been shown to be safe and to generate an immune response. However, scientists believe for practical use, these potential vaccines would require multiple doses or the addition of adjuvants, which enhance the immune response. [More]
Sinovac gets approval to begin clinical trials on Sabin Inactivated Polio Vaccine candidate

Sinovac gets approval to begin clinical trials on Sabin Inactivated Polio Vaccine candidate

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, today announced that the Company has obtained approval to begin human clinical trials on its Sabin Inactivated Polio Vaccine (or "sIPV") candidate. [More]
Study reveals molecular function of protein essential for replication of H5N1 flu virus

Study reveals molecular function of protein essential for replication of H5N1 flu virus

An international collaboration of scientists from the CEA, CNRS, University Joseph Fourier, the EMBL and the ILL has revealed the molecular function of a protein essential for replication of H5N1 influenza virus. [More]
More than half of U.S. hospitals don't require flu shots for staff, new study finds

More than half of U.S. hospitals don't require flu shots for staff, new study finds

Within weeks, flu will start spreading across North America, sickening millions of people. It will hit people with health problems and weak immune systems hardest, and may kill tens of thousands of them. [More]
Simple approach to predict viral evolution may improve vaccine efficacy

Simple approach to predict viral evolution may improve vaccine efficacy

New results from a study performed at the University of Helsinki suggest that genomic information from circulating influenza viruses can help in producing more efficient seasonal vaccines. The researchers were able to develop a simple approach for reliable real-time tracking and prediction of viral evolution based on whole-genome sequences of influenza viruses. [More]
Paracetamol provides no benefits in fighting influenza virus

Paracetamol provides no benefits in fighting influenza virus

Some doctors may recommend that patients with the flu take acetaminophen, or paracetemol, to relieve their symptoms; however, a new randomized clinical trial found no benefits to the over-the-counter medication in terms of fighting the influenza virus or reducing patients' temperature or other symptoms. [More]
NEK7 enzyme acts as on-off switch in innate immune system

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection. [More]
Yale researchers develop vaccine strategy that reduces risk of flu in cancer patients

Yale researchers develop vaccine strategy that reduces risk of flu in cancer patients

Yale Cancer Center researchers have developed a vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza. The findings were presented Dec. 6 at the 57th annual meeting of the American Society of Hematology in Orlando, Florida. [More]
Green Cross' GCFlu Quadrivalent approved to protect against four influenza strains in South Korea

Green Cross' GCFlu Quadrivalent approved to protect against four influenza strains in South Korea

Green Cross Corporation, a South Korean biopharmaceutical company, announced today that South Korea's Ministry of Food and Drug Safety has approved GCFLU QUADRIVALENT (Influenza Virus Vaccine) for immunisation of adults to help prevent disease caused by seasonal influenza (flu) virus subtype A and B. GCFlu Quadrivalent is the first locally-manufactured vaccine to cover against four influenza strains. [More]
Seqirus announces FDA approval of Fluad for seasonal influenza

Seqirus announces FDA approval of Fluad for seasonal influenza

Seqirus announced today that the US Food and Drug Administration has approved Fluad (Influenza Vaccine, Adjuvanted) to help protect those aged 65 years and older against seasonal influenza. Fluad is the first adjuvanted seasonal influenza vaccine approved in the United States; it was specifically developed for the adult population aged 65 and older. [More]
People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases. [More]
First seasonal influenza vaccine containing adjuvant now approved by FDA

First seasonal influenza vaccine containing adjuvant now approved by FDA

The U.S. Food and Drug Administration today approved Fluad, the first seasonal influenza vaccine containing an adjuvant. Fluad, a trivalent vaccine produced from three influenza virus strains (two subtype A and one type B), is approved for the prevention of seasonal influenza in people 65 years of age and older. [More]
SLU infectious diseases experts answer flu season questions

SLU infectious diseases experts answer flu season questions

A cure for the common cold isn't in the crystal ball of an infectious diseases researcher and physician at Saint Louis University's Center for Vaccine Development. [More]
Researchers devise system to accelerate the process of making life-saving vaccines

Researchers devise system to accelerate the process of making life-saving vaccines

Researchers at Brigham Young University have devised a system to speed up the process of making life-saving vaccines for new viruses. [More]
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