Insomnia News and Research RSS Feed - Insomnia News and Research

Insomnia is too little or poor-quality sleep caused by one or more of the following:

Trouble falling asleep
Waking up a lot during the night with trouble returning to sleep
Waking up too early in the morning
Having un-refreshing sleep (not feeling well rested), even after sleeping 7 to 8 hours at night

Insomnia can cause problems during the day, such as excessive sleepiness, fatigue, trouble thinking clearly or staying focused, or feeling depressed or irritable. It is not defined by the number of hours you sleep every night. Although the amount of sleep a person needs varies, most people need between 7 and 8 hours of sleep a night.
Sleeping more than 8 hours favours development of cognitive impairment in people over 65

Sleeping more than 8 hours favours development of cognitive impairment in people over 65

Sleeping more than 8 hours and less than 6 and the lack of cognitive stimulation such as reading favours the development of cognitive impairment in people over 65. This is the main conclusion of a study carried out by researchers from the Department of Pharmacy at the University CEU Cardenal Herrera and pharmacists in the Valencian Region (Spain). [More]
Benzodiazepines may contribute to respiratory problems in people with COPD

Benzodiazepines may contribute to respiratory problems in people with COPD

A group of drugs commonly prescribed for insomnia, anxiety and breathing issues "significantly increase the risk" that older people with chronic obstructive pulmonary disease, or COPD, need to visit a doctor or Emergency Department for respiratory reasons, new research has found. [More]

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes plc today announced positive topline results from a randomized, double-blind, placebo-controlled phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia. Patients treated once monthly with either 441 mg or 882 mg of aripiprazole lauroxil demonstrated statistically significant reductions from baseline in Positive and Negative Syndrome Scale (PANSS) total scores at week 12, compared to placebo (p<0.001 aripiprazole lauroxil 441 mg, p<0.001 aripiprazole lauroxil 882 mg), which was the prespecified primary endpoint in the study. Based on the positive results from this phase 3 study, Alkermes plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the third quarter of 2014. [More]
Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Astellas Pharma Inc. and Medivation Inc. today announced the submission of a variation to amend the European Marketing Authorization Application for XTANDI® (enzalutamide) capsules for the treatment of adult men with metastatic castration-resistant prostate cancer (mCRPC) who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated. [More]
Wen Dan Tang significantly reduces insomnia-related anxiety

Wen Dan Tang significantly reduces insomnia-related anxiety

Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medicine remedy Wen Dan Tang reduces insomnia-related anxiety, which may perhaps correspond to changes in the brain-gut axis. [More]

Simple tool may aid insomnia diagnoses

UK researchers have developed a “brief but versatile” tool, based on standard diagnostic criteria, to screen patients for insomnia disorder. [More]
Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive topline results from a Phase IIb trial evaluating the efficacy and safety of the investigational antipsychotic cariprazine in patients with bipolar depression. [More]

New research reveals how good sleep can help chronic pain sufferers

Chronic pain sufferers could be kept physically active by improving the quality of their sleep, new research suggests. [More]

Nightmares heighten insomnia impact on depression

Nightmares and insomnia contribute independently and additively to depression severity, cross-sectional study findings show. [More]

Six dimensions explain mania symptom variability

Researchers have identified a six-factor latent structure that they say best describes the symptomatology of hospitalized patients with bipolar mania. [More]
Ventilator patients have considerable risk of developing psychological problems

Ventilator patients have considerable risk of developing psychological problems

Fortunately, more and more people survive critical illnesses and accidents. A new Danish-American survey shows, however, that hospitalisation where the patient has received mechanical ventilation can have serious consequences. [More]
Elsevier launches Open Access, online-only journal Internet Interventions

Elsevier launches Open Access, online-only journal Internet Interventions

Elsevier, a world-leading provider of scientific, technical and medical (STM) information products and services, is pleased to announce the launch of the Open Access, online-only journal Internet Interventions. [More]
People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

People who experience chronic sleep disturbance—either through their work, insomnia or other reasons—could face an earlier onset of dementia and Alzheimer's, according to a new pre-clinical study by researchers at Temple University. [More]
Researchers identify novel protein that explains how biological clocks regulate human sleep

Researchers identify novel protein that explains how biological clocks regulate human sleep

In a series of experiments sparked by fruit flies that couldn't sleep, Johns Hopkins researchers say they have identified a mutant gene - dubbed "Wide Awake" - that sabotages how the biological clock sets the timing for sleep. [More]
Investigators urge drug regulators to provide clear evidence on statins’ side effects

Investigators urge drug regulators to provide clear evidence on statins’ side effects

At a time when the wider prescription of statins is under renewed public scrutiny, a substantial analysis of placebo-controlled randomised trials of statins has found that only a small minority of side effects reported by those taking the cholesterol-lowering drugs are actually attributable to them. [More]

Orexo signs multi-year agreement with OptumRx and UnitedHealth Group

Orexo AB, the manufacturer of ZUBSOLV® (buprenorphine and naloxone) sublingual tablets (CIII), announced a multi-year agreement with UnitedHealth Group® and OptumRx® providing preferred coverage and reimbursement of ZUBSOLV®. [More]
Prescriptions for benzodiazepines with opioid analgesics may lead to medication-related deaths

Prescriptions for benzodiazepines with opioid analgesics may lead to medication-related deaths

Prescriptions for benzodiazepines are rising in primary care, and their frequent combined use with opioid analgesics may be contributing to medication-related deaths, a finding that goes largely unreported, according to Stanford researchers. [More]

Insomnia behaviours independently influence sleep in mood disorders

Behaviours associated with controlling sleep and managing the negative effects of insomnia are independently associated with disturbed sleep in patients with anxiety or depressive disorders, US research shows. [More]
New study may open door to better diagnosis, treatment for chronic insomnia

New study may open door to better diagnosis, treatment for chronic insomnia

Johns Hopkins researchers report that people with chronic insomnia show more plasticity and activity than good sleepers in the part of the brain that controls movement. [More]
CCNAP highlights psychological issues related to cardiac diseases

CCNAP highlights psychological issues related to cardiac diseases

The congress will be held 4-5 April in Stavanger, Norway, at the Stavanger Forum. [More]