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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
New type of engineered insulin could improve treatment for diabetes patients

New type of engineered insulin could improve treatment for diabetes patients

For patients with diabetes, insulin is critical to maintaining good health and normal blood-sugar levels. However, it's not an ideal solution because it can be difficult for patients to determine exactly how much insulin they need to prevent their blood sugar from swinging too high or too low. [More]
Too much folic acid during pregnancy puts daughters at risk of diabetes, obesity later in life

Too much folic acid during pregnancy puts daughters at risk of diabetes, obesity later in life

Mothers that take excessive amounts of folic acid during pregnancy may predispose their daughters to diabetes and obesity later in life, according to a new study published today in the Journal of Endocrinology. With high dose supplements being widely available, the study calls for a need to establish a safe upper limit of folic acid intake for pregnant women. [More]
Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Chiasma Inc., a U.S. privately-held biopharma company, announced today that results from a multicenter Phase III study of the investigational new drug, octreotide capsules, were published online for early release on Feb. 9, ahead of print, by the Journal of Clinical Endocrinology & Metabolism. [More]
Scientists develop potential new therapy based on cow's immune molecules for hormone deficiencies

Scientists develop potential new therapy based on cow's immune molecules for hormone deficiencies

To help people with hormone deficiencies, scientists at The Scripps Research Institute have developed a potential new therapy based on an unlikely model: immune molecules from cows. [More]
Endogenous cannabinoids linked to weight gain in people with schizophrenia

Endogenous cannabinoids linked to weight gain in people with schizophrenia

Cannabinoids may be involved in the weight gain that occurs in people with schizophrenia who are treated with the antipsychotic olanzapine, according to a pilot study published in the Journal of Clinical Psychopharmacology by researchers at the Institut universitaire en santé mentale de Montréal and Université de Montréal. [More]
Scientists awarded Agri-Tech Catalyst funding to develop new varieties of pearl millet to tackle diabetes

Scientists awarded Agri-Tech Catalyst funding to develop new varieties of pearl millet to tackle diabetes

Scientists at Aberystwyth University's IBERS (Institute of Biological, Environmental and Rural Sciences) have been awarded £250,000 of Agri-Tech Catalyst funding for an 18 month project to develop new varieties of pearl millet. [More]
Study: Infant gut microbiota associated with healthy weight gain

Study: Infant gut microbiota associated with healthy weight gain

Researchers in Singapore and UK as part of the EpiGen consortium worked together with scientists at the Nestlé Research Center, Switzerland, on a new study on the bacterial makeup of the gut (gut microbiota) of infants in Singapore. Their study reveals that the rate of bacterial colonisation of the gut is influenced by external factors such as the method of delivery and duration of gestation. [More]
Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Isis Pharmaceuticals, Inc. announced today top-line results from a Phase 2 study of ISIS-PTP1B Rx in patients with type 2 diabetes. In the Phase 2 study patients treated with ISIS-PTP1B Rx achieved statistically significant reductions in body weight and hemoglobin A1c (HbA1c). [More]
Study looks at effect of probiotic capsule intervention on metabolic health among women with GDM

Study looks at effect of probiotic capsule intervention on metabolic health among women with GDM

In a study to be presented on Feb. 5 in an oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the effect of a probiotic capsule intervention on maternal metabolic parameters and pregnancy outcomes among women with gestational diabetes. [More]
Researchers to highlight impact of maternal glycemia on childhood obesity at The Pregnancy Meeting

Researchers to highlight impact of maternal glycemia on childhood obesity at The Pregnancy Meeting

In a study to be presented on Feb. 5 in an oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of maternal glycemia on childhood obesity and metabolic dysfunction. [More]
Study clarifies association between metformin use and lung cancer risk

Study clarifies association between metformin use and lung cancer risk

Among nonsmokers who had diabetes, those who took the diabetes drug metformin had a decrease in lung cancer risk, according to a study in Cancer Prevention Research, a journal of the American Association for Cancer Research, by Lori Sakoda, PhD, MPH, research scientist at the Kaiser Permanente Division of Research in Oakland, California. [More]
Study: About one-third of teens, young adults face social barriers to diabetes management

Study: About one-third of teens, young adults face social barriers to diabetes management

Managing type 1 diabetes is a never-ending task that requires multiple blood glucose tests, carbohydrate calculations and insulin injections or infusions. This constant effort to control the disease is daunting at any age - and it's especially challenging for teens and young adults. [More]
Study reveals how the brain can use fatty acids to control liver lipid production

Study reveals how the brain can use fatty acids to control liver lipid production

Ways of keeping the heart healthy has widened, with the discovery that the brain can help fight off hardening of the arteries. [More]
Genetic support for insulin system role in growth hormone response

Genetic support for insulin system role in growth hormone response

Genetic determinants of insulin sensitivity are positively related to spontaneous growth and response to growth hormone treatment in children born small for gestational age, researchers have found. [More]
Postprandial glucagon linked to glycaemic control in Type 1 diabetes

Postprandial glucagon linked to glycaemic control in Type 1 diabetes

Research shows that postprandial glucagon levels increase over time in children with newly diagnosed Type 1 diabetes, and are associated with worsening glycaemic control, suggesting an adjunctive treatment approach. [More]
Using antioxidant to reverse brain inflammation improves obesity, diabetes symptoms

Using antioxidant to reverse brain inflammation improves obesity, diabetes symptoms

Using an antioxidant to reverse inflammation in the brain caused by a high-fat diet greatly improves symptoms related to obesity and type II diabetes, a new study from New Zealand's University of Otago suggests. [More]
Researchers move one step closer to treating diabetes with human probiotic pill

Researchers move one step closer to treating diabetes with human probiotic pill

Science may be one step closer to treating diabetes with a human probiotic pill, according to new Cornell University research. [More]
Adropin hormone offers a promising treatment option for type 2 diabetes

Adropin hormone offers a promising treatment option for type 2 diabetes

In a study published in Molecular Metabolism, a SLU researcher has found that adropin, a hormone that regulates whether the body burns fat or sugar during feeding and fasting cycles, can improve insulin action in obese, diabetic mice, suggesting that it may work as a therapy for type 2 diabetes. [More]
Preventing obesity-related inflammation may reverse type 2 diabetes

Preventing obesity-related inflammation may reverse type 2 diabetes

Preventing inflammation in obese fat tissue may hold the key to preventing or even reversing type 2 diabetes, new research has found. [More]
Oatmeal breakfast results in greater fullness, lower hunger ratings and fewer calories intake at lunch

Oatmeal breakfast results in greater fullness, lower hunger ratings and fewer calories intake at lunch

A new study suggests that your breakfast cereal choice may affect how full you feel and how much you eat for lunch, especially if you're overweight. According to new research published in the latest issue of the Annals of Nutrition and Metabolism, scientists found that having oatmeal (Quaker Oats Quick 1-minute™) for breakfast resulted in greater fullness, lower hunger ratings and fewer calories eaten at the next meal compared to a calorie-matched breakfast of a ready-to-eat cereal (RTEC) - sugared corn flakes. [More]