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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Generic biologic drugs appear to be as effective as brand-name versions

Generic biologic drugs appear to be as effective as brand-name versions

Generic forms of a biologic drug used to treat rheumatoid arthritis, inflammatory bowel disease and psoriasis appear to be as safe and effective as their brand-name counterparts, a new Johns Hopkins Bloomberg School of Public Health analysis suggests. [More]
Scientists develop photosensitive mimics of class of signaling molecules

Scientists develop photosensitive mimics of class of signaling molecules

Teams at Ludwig-Maximilians-Universitaet in Munich and EMBL have created photosensitive mimics of a class of signaling molecules, thus enabling their actions to be regulated by light, and affording new insights into the communications networks that control cellular metabolism. [More]
FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

The U.S. Food and Drug Administration approved Adlyxin (lixisenatide), a once-daily injection to improve glycemic control (blood sugar levels), along with diet and exercise, in adults with type 2 diabetes. [More]
TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

In addition to its more obvious ills, type 2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options. [More]
Researchers identify new mechanisms capable of suppressing propagation of HCV

Researchers identify new mechanisms capable of suppressing propagation of HCV

Researchers at Osaka University, Japan uncovered the mechanisms that suppress the propagation of the hepatitis C virus (HCV) with the potential of improving pathological liver conditions. [More]
New research collaboration aims to advance clinical trials of Cell Pouch System in people with type 1 diabetes

New research collaboration aims to advance clinical trials of Cell Pouch System in people with type 1 diabetes

A new research funding agreement between the Juvenile Diabetes Research Foundation and Sernova, a clinical-stage regenerative medicine biotech, aims to address people with severe type 1 diabetes (T1D) who are hypoglycemia unaware, a condition in which a person with diabetes does not experience the usual early warning symptoms of hypoglycemia (low blood sugar) following an insulin injection. [More]
Smartphone app Pokémon Go could be new solution to rising obesity levels and Type 2 diabetes

Smartphone app Pokémon Go could be new solution to rising obesity levels and Type 2 diabetes

Leading diabetes researchers believe smartphone craze Pokémon Go could be an "innovative solution" to rising obesity levels and chronic disease. [More]
Rat study finds maternal intake of oxidised fish oil causes high newborn mortality

Rat study finds maternal intake of oxidised fish oil causes high newborn mortality

Nearly 30 percent of newborn pups born to pregnant rats fed highly oxidized ("off") fish oil died within two days after birth a new study by researchers at the Liggins Institute at the University of Auckland in New Zealand finds. [More]
Study suggests failure of specialised beta cells may lead to diabetes

Study suggests failure of specialised beta cells may lead to diabetes

The significant role of beta cell 'hubs' in the pancreas has been demonstrated for the first time, suggesting that diabetes may due to the failure of a privileged few cells, rather than the behaviour of all cells. [More]
Risk of hypoglycemia differs between SU agents, study reveals

Risk of hypoglycemia differs between SU agents, study reveals

Adding sulphonylureas (SUs) to metformin remains a commonly used strategy for treating type 2 diabetes, but individual SUs differ and may confer different risks of abnormally low blood sugar, or hypoglycemia. SUs-which include newer generation agents such as gliclazide, glipizide, glimepiride, and glibenclamide-stimulate the production of insulin in the pancreas and increase the effectiveness of insulin in the body. [More]
Breastfeeding leads to long-term metabolic changes in mothers, study shows

Breastfeeding leads to long-term metabolic changes in mothers, study shows

An interdisciplinary team of scientists at the Helmholtz Zentrum München has studied the metabolism of women with gestational diabetes after giving birth. [More]
Eating more healthy fats may lower type 2 diabetes risk

Eating more healthy fats may lower type 2 diabetes risk

Eating more unsaturated fats, especially polyunsaturated fats, in place of either dietary carbohydrate or saturated fats lowers blood sugar levels and improves insulin resistance and secretion, according to a new meta-analysis of data from 102 randomised controlled feeding trials in adults. [More]
Scientists identify marker that subdivides insulin-producing beta cells of the pancreas

Scientists identify marker that subdivides insulin-producing beta cells of the pancreas

The marker Flattop subdivides the insulin-producing beta cells of the pancreas into those that maintain glucose metabolism and into immature cells that divide more frequently and adapt to metabolic changes. [More]
New report reveals prescription medication costs may increase up to 13% in 2016

New report reveals prescription medication costs may increase up to 13% in 2016

Prescription medication costs are expected to rise at least 11 percent, and possibly up to 13 percent, in 2016, according to a new report on national trends and projections in prescription drug expenditures. [More]
Study reveals muscle activity of non-responders to diabetes interventions

Study reveals muscle activity of non-responders to diabetes interventions

It is widely accepted that physical exercise lowers the risk of developing diabetes. Yet in one in five participants in related studies this positive effect fails to materialize. [More]
Researchers use microfluidic chip to study how adipose stem cells develop into mature fat cells

Researchers use microfluidic chip to study how adipose stem cells develop into mature fat cells

A Freiburg-based research group has developed a microfluidic chip where more than one hundred apidose-derived adult stem cell cultures can grow and divide. In the human body, adipose tissue acts as a primary energy store. [More]
Scientists explore ways to make fat cells function better during obesity

Scientists explore ways to make fat cells function better during obesity

A high-fat diet makes your fat cells larger, inflamed and dysfunctional, putting you at increased risk for diabetes and cardiovascular disease. [More]
Obesity is linked with premature death, particularly in men

Obesity is linked with premature death, particularly in men

Being overweight or obese is associated with an increased risk of premature death, according to the largest ever study into obesity and death. [More]
Changes in cavefish metabolism could lead to new insights into diabetes

Changes in cavefish metabolism could lead to new insights into diabetes

Cavefish that live in dark caves with only sporadic access to food show symptoms similar to diabetes, but don't appear to experience any health problems. [More]
Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose and insulin levels. That's why a recent discovery made by Rudy Valentine and a team of researchers holds so much promise. [More]
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