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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Scientists suggest that type-1 and type-2 diabetes are result of same mechanism

Scientists suggest that type-1 and type-2 diabetes are result of same mechanism

Work by scientists at the Universities of Manchester and Auckland suggest that both major forms of diabetes are the result of the same mechanism. [More]
Complete analysis of bioseparation technologies for global biopharmaceutical markets

Complete analysis of bioseparation technologies for global biopharmaceutical markets

Reportlinker.com announces that a new market research report is available in its catalogue: ​Bioseparation Systems for Global Biopharmaceutical Markets [More]
Lilly and Boehringer Ingelheim's Basaglar (insulin glargine injection) gets FDA's tentative approval

Lilly and Boehringer Ingelheim's Basaglar (insulin glargine injection) gets FDA's tentative approval

The U.S. Food and Drug Administration today granted tentative approval for Basaglar (insulin glargine injection), which is indicated to improve glycemic control in adults with type 2 diabetes and in combination with mealtime insulin in adults and pediatric patients with type 1 diabetes. [More]
Almonds can help reduce inflammation in people with poorly controlled diabetes

Almonds can help reduce inflammation in people with poorly controlled diabetes

Evidence continues to mount supporting the role of almonds and other tree nuts as part of an overall dietary pattern that is beneficial for those with type 2 diabetes. Three new studies suggest a relationship between regular consumption of tree nuts, such as almonds, and improvement in various markers of health in type 2 diabetes. [More]
Acidity sensor helps to estimate dynamics of insulin production

Acidity sensor helps to estimate dynamics of insulin production

Many human metabolic functions only run smoothly if the acid level in the body remains neutral and stable. For humans, normal blood pH values lie between 7.35 and 7.45. By way of comparison, an empty stomach is extremely acidic, with a pH value of 1.5. [More]
UChicago Medicine and Advocate Health Care wins NIH grant to find new ways to prevent type 1 diabetes

UChicago Medicine and Advocate Health Care wins NIH grant to find new ways to prevent type 1 diabetes

The University of Chicago Medicine and Advocate Children's Hospital / Advocate Health Care have received a five-year, $1.8-million grant from the National Institutes of Health to find new ways to delay and prevent type 1 diabetes. The grant will establish the first Type 1 Diabetes TrialNet Clinical Center in Chicago. [More]
Halozyme reports revenues of $18.4 million, net loss of $16.3 million for Q2 2014

Halozyme reports revenues of $18.4 million, net loss of $16.3 million for Q2 2014

Halozyme Therapeutics, Inc. today reported financial results for the second quarter ended June 30, 2014. Financial highlights for the second quarter include revenues of $18.4 million and a net loss of $16.3 million, or $0.13 per share. [More]
Sanofi, MannKind sign licensing agreement to develop and commercialize Afrezza Inhalation Powder

Sanofi, MannKind sign licensing agreement to develop and commercialize Afrezza Inhalation Powder

Sanofi and MannKind Corporation announced today that they have entered into a worldwide exclusive licensing agreement for development and commercialization of Afrezza (insulin human) Inhalation Powder, a new rapid-acting inhaled insulin therapy for adults with type 1 and type 2 diabetes. [More]
Inadequate management common in young-onset Type 2 diabetes

Inadequate management common in young-onset Type 2 diabetes

Patients with young-onset Type 2 diabetes have worse metabolic control than those with late-onset disease, but they are less likely to receive organ-protective drugs, show data from the Joint Asia Diabetes Evaluation cohort. [More]
Notch signaling also plays important role in onset of obesity and Type 2 diabetes

Notch signaling also plays important role in onset of obesity and Type 2 diabetes

A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment. [More]
BD Medical announces retail pharmacy launch of BD AutoShield Duo

BD Medical announces retail pharmacy launch of BD AutoShield Duo

BD Medical, a segment of BD (Becton, Dickinson and Company), a leading global medical technology company, today announced the retail pharmacy launch of BD AutoShield Duo, the only pen needle with patented dual front and back-end shields that provides greater convenience and safety before and after injecting. [More]
Mental health coaching eases depression and reduces blood sugar levels in people with diabetes

Mental health coaching eases depression and reduces blood sugar levels in people with diabetes

In a rural, low-income area with a high rate of diabetes, mental health coaching significantly eased depression and reduced blood sugar levels in people with diabetes, according to a pilot study being presented here today at AADE14, the American Association of Diabetes Educators Annual Meeting & Exhibition. [More]
Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Blood sugar surges - after-meal glucose "spikes" - can be life threatening for the 29 million Americans with diabetes. Diabetic blood sugar spikes have been linked to cardiovascular disease, cancer, Alzheimer's disease, kidney failure, and retinal damage. [More]
New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

Various active substances in oral antidiabetic agents are frequently combined in the treatment of diabetes in order to achieve an effective reduction in the blood sugar. A new, very promising approach combines the substances metformin and SGLT2 inhibitors, the latter were just approved in 2012. [More]

Metformin and SGLT2 inhibitors together reduce blood sugar levels

Metformin and SGLT2 inhibitors together reduce the blood sugar levels considerably more effectively than either drug alone. [More]
Findings shed light on why PPARγ activators have side effect of promoting weight gain

Findings shed light on why PPARγ activators have side effect of promoting weight gain

The brain plays a central role in regulating appetite and whole-body metabolism. A protein known as PPARγ is important in the brain's control of food intake and body weight, but the identity of the neurons regulating this process has been unclear. [More]
Diabetes linked to increased head and neck cancer risk

Diabetes linked to increased head and neck cancer risk

People with diabetes mellitus have a significantly increased risk of developing head and neck cancer compared with those without the condition, show results of a large study conducted in Taiwan. [More]
Researchers identify possible new drug target for treating childhood blood cancer

Researchers identify possible new drug target for treating childhood blood cancer

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers at NYU Langone Medical Center report that they have identified a possible new drug target for treating the disease. [More]
Tree nuts have positive impact on glycemic control in diabetes and on metabolic syndrome criteria

Tree nuts have positive impact on glycemic control in diabetes and on metabolic syndrome criteria

Two new meta-analyses involving tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) were recently published in the online publications, British Medical Journal Open (BMJ Open) and PLOS ONE. [More]
Researchers find promising technique for type 1 diabetics to restore insulin producing cells

Researchers find promising technique for type 1 diabetics to restore insulin producing cells

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes-insulin-producing beta cells. [More]