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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Weight-loss surgery may reduce lower urinary tract symptoms

Weight-loss surgery may reduce lower urinary tract symptoms

Metabolic syndrome is linked with an increased frequency and severity of lower urinary tract symptoms, but weight loss surgery may lessen these symptoms. The findings, which come from two studies published in BJU International, indicate that urinary problems may be added to the list of issues that can improve with efforts that address altered metabolism. [More]
Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Type 1 diabetes is a complex condition to manage. It requires continuous, around the clock monitoring of blood glucose levels, which change repeatedly throughout the day and night. [More]
Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases

Alizé Pharma obtains exclusive worldwide rights to develop new therapy for bone diseases

Alizé Pharma III SAS, an Alizé Pharma group company specialized in the development of biopharmaceuticals to treat metabolic disorders and rare diseases, today announces that it has acquired exclusive worldwide rights to develop and commercialize a new family of peptides with bone anabolic properties. [More]
Closed-loop artificial pancreas system improves diabetes management in adolescents

Closed-loop artificial pancreas system improves diabetes management in adolescents

Research shows that the use of an artificial pancreas system helps to compensate for omission and underestimation of insulin boluses in adolescents with Type 1 diabetes. [More]
External artificial pancreas improves glucose control, reduces hypoglycemia risk

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret. [More]
GABA injections prevent and reverse Type 1 diabetes in mice

GABA injections prevent and reverse Type 1 diabetes in mice

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found. [More]
Researchers use EHRs to uncover hidden drug benefits

Researchers use EHRs to uncover hidden drug benefits

With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increase production. [More]
Orgenesis receives €2.015 million grant to develop potential cure for Type 1 Diabetes

Orgenesis receives €2.015 million grant to develop potential cure for Type 1 Diabetes

Orgenesis SPRL, a subsidiary of Orgenesis Inc., a leader in the emerging fields of cellular therapy and regenerative medicine, today announced that it has received the formal approval from the Walloon Region, Belgium (Service Public of Wallonia, DG06) for a €2.015 million support program for the research and development of a potential cure for Type 1 Diabetes. [More]
Study sheds light on how animals regulate body size

Study sheds light on how animals regulate body size

The proper regulation of body size is of fundamental importance, but the mechanisms that stop growth are still unclear. In a study now published in the scientific journal eLife, a research group from Instituto Gulbenkian de Ciência (IGC), led by Christen Mirth, shed new light on how animals regulate body size. [More]
Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has presented Andrew Hattersley, DM, and Mark McCarthy, MD, with the 16th Naomi Berrie Award for Outstanding Research in Diabetes, for their work on the genetics of the disease. Their research has contributed to the discovery of new forms of the disease, improvements in diagnostic methodology, and the development of more effective treatments. [More]
Dantrolene drug may be effective treatment for rare form of diabetes

Dantrolene drug may be effective treatment for rare form of diabetes

A commonly prescribed muscle relaxant may be an effective treatment for a rare but devastating form of diabetes, researchers at Washington University School of Medicine in St. Louis report. [More]
Scientists discover that brown fat could be used to manage type 2 diabetes

Scientists discover that brown fat could be used to manage type 2 diabetes

Scientists from Monash University and Stockholm University have discovered that brown fat, nicknamed the 'good fat' because it warms up the body in cold temperatures, burning up calories in the process, also 'hoovers up' excess sugar. [More]
No added benefit proven for empagliflozin in type 2 diabetes

No added benefit proven for empagliflozin in type 2 diabetes

Empagliflozin (trade name Jardiance) has been approved since May 2014 for adults with type 2 diabetes mellitus in whom diet and exercise alone do not provide adequate glycaemic control. [More]
New research suggests potential role for MEK inhibitors in type 2 diabetes

New research suggests potential role for MEK inhibitors in type 2 diabetes

A research team led by Brigham and Women's Hospital and Dana-Farber Cancer Institute has uncovered surprising new findings that underscore the role of an important signaling pathway, already known to be critical in cancer, in the development of type 2 diabetes. [More]
Research finding could have major implications for diabetes treatment

Research finding could have major implications for diabetes treatment

Harvard Stem Cell Institute researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology, have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. [More]
Social robots help diabetic children to become more confident about their futures

Social robots help diabetic children to become more confident about their futures

Social robots are helping diabetic children accept the nature of their condition and become more confident about their futures, scientists have announced following a four-and-a-half year research study. [More]
Chemical compound in coffee may help prevent damaging effects of obesity

Chemical compound in coffee may help prevent damaging effects of obesity

Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity. [More]
AADE offers self-care tips for people with diabetes

AADE offers self-care tips for people with diabetes

From Thanksgiving through New Year's Day, the holidays can be fun and heartwarming. They can also be exhausting and stressful. [More]
Stockholm researchers discover new mechanism that stimulates glucose uptake in brown fat

Stockholm researchers discover new mechanism that stimulates glucose uptake in brown fat

Research findings that can likely be used to develop a new type of medicine for type 2 diabetes are published today in the Journal of Cell Biology. Researchers at Stockholm University have discovered a new mechanism that stimulates glucose uptake in brown fat - a tissue whose primary function is to generate heat by burning fat and sugar. [More]
Zinc supplements more beneficial for some people with diabetes

Zinc supplements more beneficial for some people with diabetes

Researchers at the Johns Hopkins University School of Medicine and elsewhere have found that genetic differences may account for why zinc supplements are more beneficial to some people than to others for the prevention and control of diabetes. The results of their pilot study of a population of Old Order Amish is believed to be the first to point out the relevance of small genetic differences in response to zinc supplementation at play in diabetes management. [More]