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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

According to a new comprehensive financial analysis reported in the Journal of the American Medical Association and The Washington Post diabetes leads a list of just 20 diseases and conditions that account for more than half of all spending on healthcare in the United States. [More]
Novel mathematical model could help provide causes of complex multifactorial diseases

Novel mathematical model could help provide causes of complex multifactorial diseases

Patients with complex diseases have a higher risk of developing another. Multi-morbidity represents a huge problem in everyday clinical practice, because it makes it more difficult to provide successful treatment. [More]
Four-year Johns Hopkins program provides efficient, less expensive care for patients in East Baltimore

Four-year Johns Hopkins program provides efficient, less expensive care for patients in East Baltimore

When people with chronic health problems couldn't get around town to their doctors' appointments, a four-year Johns Hopkins program brought the appointments to them. [More]
Making muscles burn more fat and less glucose could cause diabetes, say researchers

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists from Baylor College of Medicine and other institutions. [More]
Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component. [More]
FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

FDA expands approved use of G5 Mobile Continuous Glucose Monitoring System

The U.S. Food and Drug Administration today expanded the approved use of Dexcom's G5 Mobile Continuous Glucose Monitoring System to allow for replacement of fingerstick blood glucose (sugar) testing for diabetes treatment decisions in people 2 years of age and older with diabetes. [More]
Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

The bionic pancreas system developed by Boston University investigators proved better than either conventional or sensor-augmented insulin pump therapy at managing blood sugar levels in patients with type 1 diabetes living at home, with no restrictions, over 11 days. [More]
High levels of enzyme can predict memory impairment and Type 2 diabetes

High levels of enzyme can predict memory impairment and Type 2 diabetes

An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer's patients and how that relates to cognitive decline. [More]
Researchers use worms as model system to study how gut microbiome influences disease

Researchers use worms as model system to study how gut microbiome influences disease

The billions of microorganisms living within the human digestive tract appear to play a significant role in health and disease, notably metabolic syndrome, autoimmune disorders and diabetes - but how these organisms do so is not well understood. [More]
Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

In a study published in the Journal of Lipid Research, Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels, as well as reduces body fat in an animal model. [More]
Western diet during pregnancy may increase obesity risk in offspring

Western diet during pregnancy may increase obesity risk in offspring

Diet composition around the time of pregnancy may influence whether offspring become obese, according to a new study using animal models at The Scripps Research Institute (TSRI). [More]
Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Movement of secretory molecules, such as hormones and digestive enzymes, out of the cell is known as exocytosis. This process is guided by SNARE proteins, which help the fusion of secretory vesicles with the plasma membrane. [More]
Endocrine Society applauds Novo Nordisk for pledging to limit rising insulin prices

Endocrine Society applauds Novo Nordisk for pledging to limit rising insulin prices

The Endocrine Society lauds Novo Nordisk's recent announcement that it would limit price increases for its therapies, including insulin, and hopes that other entities in the insulin supply chain including manufacturers, pharmacy benefit managers, and insurers will also demonstrate similar restraint to address this important issue. [More]
Survey: Only 1 in 3 patients discusses symptoms of hyperglycaemia with nurse or doctor

Survey: Only 1 in 3 patients discusses symptoms of hyperglycaemia with nurse or doctor

Only 1 in 3 discussed symptoms of high blood glucose levels (hyperglycaemia) with their nurse or doctor, according to a new survey of 200 people living with type 1 or type 2 diabetes, who need mealtime insulin to control their blood glucose levels. [More]
Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
Detecting inflammation in diabetic patients

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count. [More]
Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key. [More]
Study reveals new way to improve stability of common protein drugs

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face. [More]
New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

The U.S. Food and Drug Administration today approved a new indication for Jardiance (empagliflozin) to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease. [More]
Type 2 diabetes linked to long list of complications that can affect health and quality of life

Type 2 diabetes linked to long list of complications that can affect health and quality of life

T2D Lifestyle, a national survey by Health Union of more than 400 individuals living with type 2 diabetes (T2D), reveals that patients not only struggle with commonly understood complications, but also numerous lesser known ones that people do not associate with diabetes. [More]
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