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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Manipulation of gut microbes can reverse negative effects of high fat diet, researchers find

Manipulation of gut microbes can reverse negative effects of high fat diet, researchers find

Did you know that your gut sends neural messages to the brain to tell it when it is full? Researchers at the University of Georgia, Binghamton University, and Pennsylvania State University have now found that chronic consumption of high fat foods disturbs these neural messages in rats by shifting the populations of bacteria that ordinarily reside inside the gut. [More]
CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

Non-alcoholic steatohepatitis (NASH) is a serious hepatic condition that precedes hepatocellular carcinoma (HCC) and is currently untreatable. [More]
New study identifies four subtypes of human insulin producing beta cells involved in diabetes

New study identifies four subtypes of human insulin producing beta cells involved in diabetes

A new study led by nationally prominent stem cell scientist Markus Grompe, M.D., has determined the existence of at least four separate subtypes of human insulin producing beta cells that may be important in the understanding and treatment of diabetes. The findings were published online today in the journal Nature Communications. [More]
New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

Studies have shown that bariatric surgery can lead to remission of type 2 diabetes mellitus (T2DM) in rodents and humans, but this beneficial effect cannot be explained solely by weight loss. [More]
Mussels inspire scientists to attach biologically active molecule to titanium surface

Mussels inspire scientists to attach biologically active molecule to titanium surface

Titanium is used medically in applications such as artificial joints and dental implants. While it is strong and is not harmful to tissues, the metal lacks some of the beneficial biological properties of natural tissues such as bones and natural teeth. [More]
Study estimates global trends in diabetes prevalence

Study estimates global trends in diabetes prevalence

A female researcher from UPM is involved in a study that estimates the global prevalence of diabetes and anticipates future trends. [More]
Sex-related difference could have impact on treatment of metabolic diseases

Sex-related difference could have impact on treatment of metabolic diseases

In health research, most preliminary studies in animals only examine effects of drug treatment in one sex, assuming that males and females will have few differences in how a drug works. [More]
BetterYou’s transdermal MagnesiumOil Spray trio certified on Informed-Sport programme

BetterYou’s transdermal MagnesiumOil Spray trio certified on Informed-Sport programme

A transdermal trio of MagnesiumOil Sprays by health pioneers BetterYou has been certified for inclusion in the kit bags of the world’s elite sporting stars and coaches. [More]
AMPK protein activated during fasting regulates hunger neurons in the brain

AMPK protein activated during fasting regulates hunger neurons in the brain

Neurons in the brain that control hunger are regulated by AMPK, a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School in Neuron on July 6, 2016. [More]
Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

When Amy Sweat was 19 years old, while she was in the hospital recovering from surgery, she was diagnosed with Type 2 diabetes. Ms. Sweat was treated for her diabetes, first on oral drugs, then on increasingly larger doses of insulin, but the years went by and she never was able to achieve good blood sugar control. [More]
Pediatric endocrinologist outlines top summertime tips for kids with Type 1 diabetes

Pediatric endocrinologist outlines top summertime tips for kids with Type 1 diabetes

For kids, the perfect summer can mean sleeping in, eating whenever hunger strikes, playing outdoors in the sun, swimming and staying up late. But for children with Type 1 diabetes, all of the above, and the general lack of schedule, can wreak havoc with their blood sugar levels. [More]
Study links proteins involved in cell division to insulin signaling

Study links proteins involved in cell division to insulin signaling

Proteins that play key roles in the timing of cell division also moonlight in regulating blood sugar levels, UT Southwestern Medical Center researchers have found. [More]
Appetite hormone CART helps increase insulin secretion, reduce glucagon production

Appetite hormone CART helps increase insulin secretion, reduce glucagon production

The study shows that the appetite hormone CART not only controls the sensation of satiety, but it also helps increase insulin secretion and decrease glucagon production. [More]
Excess or insufficient sleep may increase diabetes risk in men

Excess or insufficient sleep may increase diabetes risk in men

Men who sleep either fewer or more hours than average may face a greater risk of developing diabetes, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Experimental lipid-lowering drug improves glucose control in diabetic patients

Experimental lipid-lowering drug improves glucose control in diabetic patients

High triglycerides -- a type of fat, or lipid, in the blood -- increase the risk of heart disease and perhaps type 2 diabetes. For the first time, it has been shown that profoundly lowering triglycerides in diabetics improves their insulin sensitivity over time, which helps them maintain healthy glucose - blood sugar -- levels. [More]
Pioglitazone effective in diabetes patients with NASH

Pioglitazone effective in diabetes patients with NASH

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows. [More]
Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others. [More]
The scent dogs smell on diabetics’ breath could offer key to new tests

The scent dogs smell on diabetics’ breath could offer key to new tests

An increase in the level of the chemical isoprene may be the warning sign some dogs can detect in the breath of patients with type 1 diabetes who are reaching risky low levels of blood sugar, according to research by the University of Cambridge. [More]
Blood mannose levels could help predict type 2 diabetes risk

Blood mannose levels could help predict type 2 diabetes risk

Even if you are not overweight, your mannose levels may indicate whether you're at risk for type 2 diabetes (T2D) or insulin resistance (IR), a Swedish study shows. [More]
Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer. [More]
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