Interferon Gamma (IFNγ) News and Research

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How early interferon curbs SARS-CoV-2 infection

A new study available in the Journal of Experimental Medicine focuses on the importance of interferon in SARS-CoV-2 infection.

30 Aug 2021

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Researchers have found that both type I and type III interferons can inhibit SARS-CoV-2 infection in human intestinal cells, but type III interferons can act faster and for a longer period, making them suitable for potential therapeutics.

17 Jun 2021

Researchers develop smart genetic reference library for locating disease-causing mutations

Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations.

3 Mar 2017

Penn scientists discover clues that could lead novel therapies for preventing heart failure

Of the more than 700,000 Americans who suffer a heart attack each year, about a quarter go on to develop heart failure.

7 Feb 2017

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own.

21 Dec 2016

Research provides insight into molecular mechanisms involved in immune response to HBV

The innate immune system in mammals defends against infection from viruses and other microbial infections.

28 Nov 2016

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

The study began by taking the medical history of 11 children, all of whom had a disorder due to mycobacteria infections, as the basis. All were discovered to have the same phenotype with the same mutation, which was located in the interferon-gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction.

27 Oct 2016

Researchers explain why explain why some tumors recur after immunotherapy

Immunotherapy is a new and highly promising form of treatment for cancer. In many patients, however, tumors recur after immunotherapy.

7 Oct 2016

Novel immunotherapy shows promise against AML in clinical trial

A new type of immunotherapy shows promise against cases of acute myeloid leukemia (AML) that recur after treatment or that never respond to therapy in the first place.

21 Sep 2016

USPSTF recommends screening for LTBI in populations at increased risk

The U.S. Preventive Services Task Force recommends screening for latent tuberculosis infection in populations at increased risk.

7 Sep 2016

Fiocruz to start phase II clinical trials of novel vaccine for schistosomiasis

The Oswaldo Cruz Foundation at Rio de Janeiro, Brazil, will start the phase II clinical trials of a vaccine for schistosomiasis, called 'Sm14 Vaccine'.

26 Aug 2016

Immune system signaling can directly affect social behavior

Using a systems-biology approach, scientists at the University of Massachusetts Medical School made a startling discovery that immune system signaling can directly affect, and even change, social behavior in mice and other model animals.

18 Jul 2016

Researchers find immune system directly affects, controls social behavior

In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects - and even controls - creatures' social behavior, such as their desire to interact with others.

14 Jul 2016

Key differences in immune response may explain young children’s proneness to infecion

Schools are commonly known as breeding grounds for viruses and bacteria, but this may not necessarily be linked to hygiene.

4 Jul 2016

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria.

17 Jun 2016

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system.

14 Jun 2016

New skin test for TB infection proves safe, effective in clinical trials

A new skin test for tuberculosis infection has proven safe, easy to administer and accurate in two Phase III clinical trials, according to research presented at the ATS 2016 International Conference.

19 May 2016

Food components can have significant influence on immune system

An international team of researchers under the leadership of the LIMES Institute and the excellence cluster ImmunoSensation of the University of Bonn unraveled a new regulatory mechanism how food components and environmental factors influence the immune system.

18 May 2016

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine.

12 Apr 2016