Intestinal Cancer News and Research

RSS

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Researchers identify key factors involved in DNA repair mechanism

Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies.

12 Nov 2023

Expertise in cancer treatment could be used to find a cure for endometriosis

Endometriosis: If we utilize all the knowledge we have about cancer, there is reason to hope that effective diagnosis and treatments can be developed to combat the female condition 'everybody' is talking about.

5 Jun 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

BGI Genomics and Zentya collaborate to launch first-ever fecal DNA tests for colorectal cancer in Slovakia

BGI Genomics is pleased to announce the launch of COLOTECTTM 1.0 in Slovakia, in collaboration with its local partner, Zentya.

30 Mar 2023

In Jackson, the water is back, but the crisis remains

In mid-September, Howard Sanders bumped down pothole-ridden streets in a white Cadillac weighed down with water bottles on his way to a home in Ward 3, a neglected neighborhood that he called "a war zone."

23 Sep 2022

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

The new research findings help to understand mechanisms that lead to different types of intestinal tumors. They show that the Lef1 gene suppresses the development and growth of colorectal cancer by restricting the formation of cancer stem cell niches.

18 Nov 2021

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg.

19 Apr 2021

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

The gut plays a central role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide.

11 Jan 2021

Study: R-spondin growth factor reduces intestinal tumors in early phase of colorectal cancer

Colorectal cancer constitute the third most common cancer in the Western world. Their incidence constantly increases as the population ages, and despite recent advances in colorectal cancer therapy, the cancer metastasizes in every third of colorectal cancer patients, and a significant part of these patients eventually die from the disease

24 Sep 2020

Arrhythmic gut bacteria signatures predict type 2 diabetes risk

The microbial composition of the intestines is complex and varies widely from one individual to another. Many factors such as environmental factors, lifestyle, genetics or illnesses affect the intestinal ecosystem of helpful gut bacteria.

6 Jul 2020

Study identifies a previously unknown mechanism that contributes to intestinal cancer

A MedUni Vienna study group has identified a previously unknown mechanism involved in the development of intestinal cancer: The bacterial microbiome activates the so-called immune checkpoint Ido1 in Paneth cells, a special cell that is only found in the gastrointestinal tract, thereby preventing local intestinal inflammation.

18 Jun 2020

MCL1 protein essential in protecting the intestine against cancer development

An international team of researchers from the University of Zurich, the University Hospital Zurich, Heidelberg and Glasgow has identified a novel function for the cell death regulating protein MCL1: It is essential in protecting the intestine against cancer development – independent of bacterial-driven inflammation.

18 Mar 2020

Oral vaccination with cholera toxin helps counteract age-associated obesity

Here the research team tested a safe and well-established microbe-based immune adjuvant to restore immune homeostasis and counteract inflammation-associated obesity in animal models.

19 Nov 2019

Certain cancer drugs induce stem cell plasticity in colorectal cancer

Scientists from the German Cancer Research Center and the Mannheim University Medical Center have now discovered that a certain group of cancer drugs (MEK Inhibitors) activates the cancer-promoting Wnt signaling pathway in colorectal cancer cells.

16 May 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

Study reports increased risk of death in children with inflammatory bowel disease

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet in Sweden published in the journal Gastroenterology reports.

19 Oct 2018

Body organs undergo structural changes in response to diet

Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to Carnegie's Rebecca Obniski, Matthew Sieber, and Allan Spradling.

20 Sep 2018

Social environment plays substantial role in progression of noncontagious diseases

What if social behavior affected the progression of even noncontagious diseases? This is precisely what has been demonstrated by French CNRS teams, with support from the French National Research Institute for Sustainable Development, Paris-Sud University, the University of Montpellier, the French Alternative Energies and Atomic Energy Commission, and colleagues from Spain and Australia.

3 Sep 2018

Researchers find identity of stem-cell niche of the colon

Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible for its continuous renewal.

7 Jun 2018