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Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix Corp. is pleased to announce the formation of an international Clinical Steering Committee for the RVX-208 "apabetalone" Phase 3 clinical trial BETonMACE assessing major adverse cardiac events (MACE) in high-risk vascular patients with diabetes mellitus and a recent Acute Coronary Syndrome event. BETonMACE is expected to start in the fall of 2015. [More]
Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development. [More]
Integrated treatment required for diabetes-eating disorder combination

Integrated treatment required for diabetes-eating disorder combination

As they reach their teens, many with type 1 diabetes discover that the disease provides a secret weapon for losing weight. By restricting or reducing the amount of insulin they inject, they can eat just about anything they want and control their weight. [More]
Girls are born with weaker spines compared to boys, study finds

Girls are born with weaker spines compared to boys, study finds

Looking at measurements of the vertebrae - the series of small bones that make up the spinal column - in newborn children, investigators at Children's Hospital Los Angeles found that differences between the sexes are present at birth. Results of the study, now online in advance of publication in the August issue of the Journal of Pediatrics, suggest that this difference is evolutionary, allowing the female spine to adapt to the fetal load during pregnancy. [More]
3SBio purchases entire equity interest in Zhejiang Wansheng

3SBio purchases entire equity interest in Zhejiang Wansheng

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced that it has acquired the entire equity interest in Zhejiang Wansheng Pharmaceutical Co., Ltd a limited liability company incorporated in the PRC for an aggregate consideration of RMB 528 million. [More]
UC San Diego researchers identify pivotal player in diabetic kidney disease

UC San Diego researchers identify pivotal player in diabetic kidney disease

Tapping the potential of metabolomics, an emerging field focused on the chemical processes of metabolism, researchers at University of California, San Diego School of Medicine have identified a new and pivotal player in diabetic kidney disease. [More]
Research suggests that only one in three older Americans have diabetes under control

Research suggests that only one in three older Americans have diabetes under control

Only one in three older Americans have their diabetes under control as measured by guidelines set by the American Diabetes Association, new Johns Hopkins Bloomberg School of Public Health research suggests. [More]
Dietary phosphate appears to cause spikes in blood phosphorus levels

Dietary phosphate appears to cause spikes in blood phosphorus levels

Phosphates artificially added to dairy and cereal products appear to cause bigger spikes in blood phosphorus levels than naturally occurring phosphates, potentially putting harmful stress on kidneys. Too much dietary phosphate stiffens blood vessels, enlarges the heart and is bad for bones, but a new study by Houston Methodist researchers suggests it matters where the phosphates come from. [More]
Researchers use iPSCs to explore new treatments for kidney disease

Researchers use iPSCs to explore new treatments for kidney disease

One promising way to treat diseased or damaged kidneys is cell therapies that include the transplantation of renal progenitor cells, which can then develop into the cells needed for full recovery. Acquiring a sufficient number of progenitor cells has been difficult, however, which is why scientists have considered induced pluripotent stem cells (iPSCs), since they can be expanded at significantly high levels and then differentiated into the progenitors. [More]
MU researcher receives $2.2 million grant to develop system to display clear blood pressure information

MU researcher receives $2.2 million grant to develop system to display clear blood pressure information

Physicians receive lots of information about patients in a short amount of time, and sometimes that information is scattered, disorganized or difficult to comprehend. Now, a researcher at the University of Missouri School of Medicine has received funding to develop a simpler and clearer system to display blood pressure information. [More]
New approach holds great promise for developing effective treatments for human mitochondrial diseases

New approach holds great promise for developing effective treatments for human mitochondrial diseases

Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases. [More]
New drug patiromer could improve potassium levels of patients with diabetic kidney disease

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA. [More]
Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients

Wayne State researchers explore effects of Tocotrienol-rich fraction from palm oil in ESRD patients

End-stage renal disease (ERSD) is the last stage of chronic kidney disease where the kidneys function at under 10 to 15 percent of their normal capacity. At this stage, kidneys cannot effectively remove waste or excess fluid from the blood system, and dialysis or a kidney transplant is necessary to live. [More]
University of Leeds scientists uncover genes implicated in common inherited diseases

University of Leeds scientists uncover genes implicated in common inherited diseases

Scientists from the University of Leeds have uncovered the most comprehensive list yet of genes implicated in a group of common inherited diseases. [More]
Resverlogix and Hepalink close license agreement, sign definitive stock purchase agreement

Resverlogix and Hepalink close license agreement, sign definitive stock purchase agreement

Resverlogix Corp. announced today that it has closed a license agreement and formally entered into a definitive stock purchase agreement with Shenzhen Hepalink Pharmaceutical Co., Ltd.. [More]
Southern Research receives $22 million to support HIV cure initiative

Southern Research receives $22 million to support HIV cure initiative

Southern Research has been awarded a seven-year contract of up to $22 million to support research that could contribute to the cure of HIV disease. Under this contract, Southern Research will develop and standardize assays that quantitate latent reservoirs of HIV. [More]
Blood-borne molecule promotes age-related cognitive decline

Blood-borne molecule promotes age-related cognitive decline

A blood-borne molecule that increases in abundance as we age blocks regeneration of brain cells and promotes cognitive decline, suggests a new study by researchers at UC San Francisco and Stanford School of Medicine. [More]
DaVita Kidney Care offers recipes to help CKD patients maintain healthy diet during Fourth of July weekend

DaVita Kidney Care offers recipes to help CKD patients maintain healthy diet during Fourth of July weekend

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, offers recipes that can help people with chronic kidney disease (CKD) maintain a healthy diet during the Fourth of July weekend. [More]
DaVita Kidney Care recognizes June as National Men's Health Month

DaVita Kidney Care recognizes June as National Men's Health Month

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, recognizes the month of June as National Men's Health Month and the importance of bringing awareness to the health care issues that affect men. [More]
New strategies may help clinicians and hospitals better manage patients with chronic conditions

New strategies may help clinicians and hospitals better manage patients with chronic conditions

Experts have identified strategies for using electronic health records to improve care for patients with chronic kidney disease. The guidance, which will appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies. [More]
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