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Baxter submits BAX 855 NDA to Japan's MHLW for treatment of hemophilia A patients

Baxter submits BAX 855 NDA to Japan's MHLW for treatment of hemophilia A patients

Nektar Therapeutics reported today that partner Baxter International Inc. announced that the company has submitted a new drug application (NDA) to Japan's Ministry of Health, Labour and Welfare for the approval of BAX 855, an investigational, extended half-life recombinant factor VIII (rFVIII) treatment based on ADVATE [Antihemophilic Factor (Recombinant)] for patients over 12 years of age with hemophilia A. [More]
Managing autosomal dominant polycystic kidney disease: an interview with Dr Richard Sandford, University of Cambridge

Managing autosomal dominant polycystic kidney disease: an interview with Dr Richard Sandford, University of Cambridge

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited kidney diseases. It's also one of the most common reasons that people require dialysis or transplantation... [More]
DFG selects 10 researchers to receive 2015 Heinz Maier-Leibnitz Prize

DFG selects 10 researchers to receive 2015 Heinz Maier-Leibnitz Prize

This year's recipients of the most important prize for early career researchers in Germany have been announced. The selection committee, appointed by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) and the German Federal Ministry of Education and Research (BMBF), has chosen ten researchers, five women and five men, to receive the 2015 Heinz Maier-Leibnitz Prizes. [More]
Prolong Pharmaceuticals' SANGUINATE granted FDA Orphan Drug Designation for SCD treatment

Prolong Pharmaceuticals' SANGUINATE granted FDA Orphan Drug Designation for SCD treatment

Prolong Pharmaceuticals, LLC, a biopharmaceutical company dedicated to developing products for the treatment of anemias, cancers and their debilitating comorbidities, announced today that the U.S. Food and Drug Administration has granted Orphan Drug Designation for its flagship product SANGUINATE for the treatment of Sickle Cell Disease (SCD). [More]
Medication adherence interventions for heart failure patients

Medication adherence interventions for heart failure patients

Unlike some conditions, heart failure must be managed by patients taking prescriptions for the rest of their lives. Individuals who do not take their heart medication as prescribed have increased risks of mortality and hospitalization and higher health care costs. [More]
Treating common gum disease in CKD patients could reduce heart disease risk

Treating common gum disease in CKD patients could reduce heart disease risk

Treating a common gum condition in chronic kidney disease (CKD) patients could significantly reduce their risk of potentially fatal heart disease, Aston University researchers say. [More]
New oral drug shows promise in patients with chronic kidney disease

New oral drug shows promise in patients with chronic kidney disease

Patients with chronic kidney disease may be treated with a class of medications called Renin Angiotensin Aldosterone System inhibitors (RAASI's). Although these drugs protect the heart and kidney, a significant percentage of patients develop a dangerous side effect -- high potassium levels in the blood (hyperkalemia). [More]
Six winners share £2 million to develop cutting-edge technology to prevent kidney disease

Six winners share £2 million to develop cutting-edge technology to prevent kidney disease

SIX winners, announced today, will receive a share of over £2 million as part of a Small Business Research Initiative competition aimed at developing cutting-edge technology solutions to help kidney patients. [More]
DaVita Kidney Care celebrates its dietitians and social workers

DaVita Kidney Care celebrates its dietitians and social workers

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, is celebrating its more than 3,600 dietitians and social workers during March for their distinctive and important roles in patient care. [More]
Penn surgeons develop new tools to identify joint replacement patients at risk for serious complications

Penn surgeons develop new tools to identify joint replacement patients at risk for serious complications

Orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania have developed two new prediction tools aimed at identifying total hip and knee replacement patients who are at-risk of developing serious complications after surgery. [More]
New Quest Diagnostics study analyses impact of ACA in promoting earlier diagnosis of diabetes

New Quest Diagnostics study analyses impact of ACA in promoting earlier diagnosis of diabetes

People in states that expanded Medicaid under the Affordable Care Act (ACA) are far more likely to be newly identified with diabetes than in states that elected not to expand the public health care program, finds a new study by researchers at Quest Diagnostics. [More]
Regulus' RG-012 receives orphan medicinal product designation in EU for treatment of Alport syndrome

Regulus' RG-012 receives orphan medicinal product designation in EU for treatment of Alport syndrome

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that the European Commission has granted orphan medicinal product designation for RG-012, a single stranded, chemically modified oligonucleotide that binds to and inhibits the function of microRNA-21 ("miR-21") for the treatment of Alport syndrome, a life-threatening genetic kidney disease with no approved therapy. [More]
TVA Medical's novel hemodialysis access technique shows positive outcomes in clinical study

TVA Medical's novel hemodialysis access technique shows positive outcomes in clinical study

TVA Medical, Inc., today announced promising results from a clinical study evaluating a novel hemodialysis access technique that has the potential to revolutionize vascular access for patients with chronic kidney disease without the use of traditional open surgery. [More]
DCR representatives to present health-related quality posters at NKF's 2015 Spring Clinical Meeting

DCR representatives to present health-related quality posters at NKF's 2015 Spring Clinical Meeting

DaVita Clinical Research, a specialty contract research organization with services spanning the full spectrum of drug and device development and subsidiary of DaVita HealthCare Partners Inc., today announced that company representatives will present health-related quality posters at National Kidney Foundation's 2015 Spring Clinical Meeting, which takes place March 25-29, 2015 in Dallas. [More]
Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

Kidney transplantation outcomes from deceased African-American donors may improve through rapid testing for apolipoprotein L1 gene (APOL1) renal risk variants at the time of organ recovery, according to a new study led by researchers at Wake Forest Baptist Medical Center. [More]
Researchers develop noninvasive method to detect kidney cancer early

Researchers develop noninvasive method to detect kidney cancer early

If kidney cancer is diagnosed early — before it spreads — 80 percent of patients survive. However, finding it early has been among the disease's greatest challenges. [More]
Study provide new insights into why childhood CKD may worsen to kidney failure

Study provide new insights into why childhood CKD may worsen to kidney failure

Study results published today in the National Kidney Foundation's American Journal of Kidney Diseases provide new insights into why a child's chronic kidney disease (CKD) may worsen to kidney failure. [More]
Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Cardiovascular researchers at The Ohio State University Wexner Medical Center have shown that a protein known as MG53 is not only present in kidney cells, but necessary for the organ to repair itself after acute injury. Results from this animal model study are published in the journal Science Translational Medicine. [More]
Endovascular aneurysm repair procedure can extend lives even in high-risk patients: Study

Endovascular aneurysm repair procedure can extend lives even in high-risk patients: Study

Minimally invasive surgery can prevent a fatal rupture of an abdominal aortic aneurysm. [More]
Lancet study: Most people lack access to life-saving treatments for kidney failure

Lancet study: Most people lack access to life-saving treatments for kidney failure

New estimates published in The Lancet indicate that at best only half of people worldwide needing kidney dialysis or transplantation to treat kidney failure in 2010 received it. This suggests that at least 2.3 million people may have died prematurely from kidney failure because they could not access this life-saving treatment. [More]
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